Unlock instant, AI-driven research and patent intelligence for your innovation.

Preparing method of morinda officinalis total oligose

A technology of oligosaccharides and Morinda officinalis, which is applied in the field of medicine, can solve the problems of low yield, unfavorable industrial production, complex process, etc., and achieve the effect of simplifying the preparation process, low cost, and simple and easy process

Inactive Publication Date: 2017-08-18
GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY
View PDF6 Cites 7 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The method is complex in process, and the yield of total oligosaccharides is only about 5%, which is low and unfavorable for industrial production

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparing method of morinda officinalis total oligose
  • Preparing method of morinda officinalis total oligose
  • Preparing method of morinda officinalis total oligose

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] like figure 1 Shown, a kind of preparation method of Radix Morinda officinalis total oligosaccharide comprises the steps:

[0032] (a) Take 1 kg of Morinda officinalis fresh medicinal material, remove impurities, and pulverize;

[0033] (b) Take the crushed Morinda officinalis fresh medicinal material, add 8 times the amount of distilled water, boil for 2 hours, filter, and add 8 times the amount of distilled water to the filter residue

[0034] Distilled water, boiled for 2 h, filtered, combined filtrates, concentrated under reduced pressure at 60-80 °C to obtain a concentrated solution;

[0035] (c) Add ethanol to the concentrated solution, adjust the ethanol concentration to 90%, refrigerate, let stand for 24 hours, redissolve the precipitate in hot water,

[0036] Cool to room temperature, then add ethanol, adjust the ethanol concentration to 90%, refrigerate, and let it stand for 24 hours to obtain a precipitate, which is the crude product of Morinda officinalis ...

Embodiment 2

[0051] A preparation method of Morinda officinalis total oligosaccharides, comprising the steps of:

[0052] (a) 5 kg fresh medicinal material of Morinda officinalis, remove impurities, and pulverize;

[0053] (b) Take the crushed Morinda officinalis fresh medicinal material, add 10 times the amount of distilled water, boil for 1.5 h, filter, and add 8 times the amount to the filter residue

[0054] Distilled water, boiled for 2 h, filtered, combined filtrates, concentrated under reduced pressure at 60-80 °C to obtain a concentrated solution;

[0055] (c) Add ethanol to the concentrated solution, adjust the ethanol concentration to 90%, refrigerate, let stand for 24 hours, redissolve the precipitate in hot water,

[0056] Cool to room temperature, then add ethanol, adjust the ethanol concentration to 90%, refrigerate, and let it stand for 24 hours to obtain a precipitate, which is the crude product of Morinda officinalis total oligosaccharides;

[0057] (d) Redissolve the cr...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a preparing method of morinda officinalis total oligose. The preparing method comprises the steps of removing impurities of morinda officinalis fresh medicinal materials, and smashing the morinda officinalis fresh medicinal materials; adding distilled water to conduct extraction, conducting decompression and concentration on an extraction solution, and adding ethanol into the concentrated solution to conduct precipitation to obtain a coarse product of morinda officinalis total oligose; again dissolving the coarse product of morinda officinalis total oligose into water, conducting elution through anion exchange resin to collect an elution solution, conducting decompression and concentration on the elution solution and afterwards adding ethanol to conduct precipitation, and conducting still standing, suction filtering and drying to obtain morinda officinalis total oligose. According to the preparing method of the morinda officinalis total oligose, the manufacturing technology of the morinda officinalis total oligose is simplified, only ethanol and water are used as solvents, other harmful agents are not utilized, and environment pollution is not caused; meanwhile, the raw materials are all fresh materials, the processing steps of the medicinal materials can be omitted, the energy is fully saved, the purity of the prepared morinda officinalis total oligose reaches 80%, the yield reaches 30% or above, the technology is simple and easy to implement, the cost is low, the preparing method of the morinda officinalis total oligose is suitable for industrialized production, and industrialization is easily formed.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a preparation method of Morinda officinalis total oligosaccharides. Background technique [0002] The traditional Chinese medicine Morinda officinalis, also known as Jichangfeng, corn vine, triangular vine, etc., is the dry root of the perennial climbing woody vine Morinda officinalis How of Rubiaceae, mainly distributed in Guangdong, Guangxi, Fujian It is one of the four famous southern medicines in my country in the tropical and subtropical regions of Hainan, Hainan and other provinces. Morinda officinalis is sweet and pungent in taste, slightly warm in nature, and has the effects of invigorating kidney yang, strengthening muscles and bones, and dispelling wind-dampness. Morinda officinalis was first recorded in "Shen Nong's Materia Medica", and it has been recorded in the herbal medicines published in the past dynasties of our country. The "Pharmacopoeia of the Pe...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C07H1/08C07H3/06C07H3/02C07H3/04C08B37/00
CPCC07H1/08C07H3/02C07H3/04C07H3/06C08B37/0003
Inventor 陈地灵杨俭帅欧唐晓萃谢意珍吴清平
Owner GUANGDONG INST OF MICROBIOLOGY GUANGDONG DETECTION CENT OF MICROBIOLOGY