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Drug for preventing and treating rabbit pasteurellosis

A technology for Pasteurella rabbits and medicines, applied in the field of medicines for preventing and treating Pasteurellosis of rabbits, can solve problems such as imprecise formulations, food safety threats of rabbit meat, hidden dangers of drug residues, etc.

Inactive Publication Date: 2017-09-08
HEBEI UNIV OF ENG
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

For example, the domestic Pasteurella vaccine in rabbits has good preventive efficacy, but in practice, it has been found that some rabbit breeders have many problems in the immunization procedure, vaccination time, and inoculation dose, which lead to unsatisfactory immune effect or even immune failure. What's more, immunization is not done, which leads to the occurrence of this disease; commercially available anti-polyvalent serum can be used for emergency prevention and treatment of this disease, but because of its high cost, and it still needs to be used in conjunction with antibacterial western medicine treatment, in the Seldom use in clinical practice, fail to popularize and apply on a large scale so far; Commercially available western medicine such as antibiotics (penicillin, streptomycin, tetracycline etc.), sulfonamides etc. Long-term application, even indiscriminate use and abuse, its curative effect decreases year by year, and the dosage increases year by year. It is an indisputable fact that drug-resistant strains continue to form, and there are potential hidden dangers of drug residues, which pose a threat to rabbit meat food safety; other commercially available Although traditional Chinese veterinary medicines such as Tubailing and Tubaikang do not have the disadvantages of the above-mentioned western medicines, they also have some technical defects in the formulation and application methods. Feeding the drug powder directly with mixing materials delays the absorption rate of the active ingredients of the drug by sick rabbits, and the control effect is not satisfactory

Method used

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  • Drug for preventing and treating rabbit pasteurellosis
  • Drug for preventing and treating rabbit pasteurellosis

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Test time: October 2011.

[0018] Place for testing: Zhao Wenhua Rabbit Farm in Yutian County, Hebei Province.

[0019] The test group of rabbits: 92-105 days old, 226 commercial generation Qingzilan rabbits, rabbit pasteurellosis occurred due to climate change and continuous rain. The feeding and management conditions were the same, and none of them were vaccinated against rabbit pasteurella vaccine.

[0020] Drug for testing: namely the pure Chinese medicine preparation of the present invention, each raw material drug is purchased from Dongfang Medicine City, Anguo City, Hebei Province, and its composition is expressed in parts by mass: 5 parts of honeysuckle, 5 parts of eucalyptus leaves, 5 parts of raw gypsum, 5 parts of mother mother, 4 parts of magnolia, 4 parts of skullcap, 4 parts of Phellodendron, 4 parts of Qinpi, 3 parts of purple pearl, 3 parts of agrimony, 3 parts of lotus root, 3 parts of madder, 2 parts of rhubarb, 2 parts of gardenia, 2 parts of licorice...

Embodiment 2

[0034] Test time: March 2012.

[0035] Place for testing: Liuerni Rabbit Farm in Zunhua City, Hebei Province.

[0036] The test group of rabbits: 90-115 days old, 282 commercial generation California rabbits, rabbit pasteurellosis occurred due to factors such as climate change and crowd crowding. The feeding and management conditions were the same, and none of them were vaccinated against rabbit Pasteurella vaccine.

[0037] Drug for testing: namely the pure Chinese medicine preparation of the present invention, the purchase of each raw material is the same as in Example 1, and its composition is expressed in parts by mass: 15 parts of honeysuckle, 15 parts of eucalyptus, 15 parts of raw gypsum, 15 parts of anemarrhena, magnolia magnolia 12 parts, 12 parts of Scutellaria baicalensis, 12 parts of Cortex Phellodendri, 12 parts of Qinpi, 9 parts of Purple Pearl, 9 parts of Agrimony, 9 parts of Ou Jie, 9 parts of Rubia, 6 parts of Rhubarb, 6 parts of Gardenia, 6 parts of Licorice,...

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Abstract

The invention relates to a drug for preventing and treating rabbit pasteurellosis, belonging to the technical field of pharmaceutical and medical engineering. The drug contains the following components in parts by mass: 5-15 parts of honeysuckles, 5-15 parts of eucalyptus leaves, 5-15 parts of raw gypsum, 5-15 parts of rhizoma anemarrhenae, 4-12 parts of flos magnoliae, 4-12 parts of radix scutellariae, 4-12 parts of cortex phellodendri, 4-12 parts of cortex fraxini, 3-9 parts of folium callicarpae pedunculalae, 3-9 parts of herba agrimoniae, 3-9 parts of nodus nelumbinis rhizomatis, 3-9 parts of radix rubiae, 2-6 parts of rheum officinale, 2-6 parts of fructus gardenia, 2-6 parts of radix glycyrrhizae and 2-6 parts of Chinese dates. The drug is prepared by the steps of drying the Chinese herbal medicines in the sun, weighing the Chinese herbal medicines, crushing the Chinese herbal medicines into powder, sieving by virtue of a 60-mesh sieve, and uniformly stirring. In a clinical application process, the drug is soaked into boiling water for 30-60 minutes to adequately dissolve and separate effective components of the drug, so that the in-vivo absorption of diseased rabbits is benefited; meanwhile, a small amount of sugar and Vc are added, so that the pesticide effect can be improved. The drug is relatively high in clinical cure rate and has no untoward effect, the drug resistance is unlikely to be generated, and no drug is remained in rabbit meat; and the required raw materials are easily available, and the drug is easy to prepare and convenient to use and can be widely popularized and applied in big, medium and small warrens.

Description

[0001] Technical field: [0002] The invention belongs to the technical field of medicine and medical engineering, in particular to a medicine for preventing and treating pasteurellosis in rabbits. [0003] Background technique: [0004] Since the reform and opening up, my country's rabbit industry has developed rapidly. The scale of raising rabbits continues to expand, and the breeding methods are developing towards industrialization and intensification, which basically meets people's market demand for rabbit meat and rabbit fur. However, rabbit disease is still an important factor that endangers and restricts the healthy and sustainable development of the rabbit industry. In particular, certain infectious diseases are even more harmful, such as pasteurellosis in rabbits (commonly known as rabbit failure). The disease is caused by Pasteurella multocida and is characterized by acute sepsis and hemorrhagic inflammation. Rabbits are highly sensitive to this bacteria, which ofte...

Claims

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Application Information

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IPC IPC(8): A61K36/8964A61P31/04A61K33/06
CPCA61K9/0056A61K33/06A61K36/355A61K36/484A61K36/539A61K36/575A61K36/61A61K36/62A61K36/63A61K36/708A61K36/725A61K36/73A61K36/74A61K36/744A61K36/756A61K36/85A61K36/8964A61K2300/00
Inventor 贾庄德阎瑞峰鹿峰峰杨利张晶晶张彦军杨秀林
Owner HEBEI UNIV OF ENG