Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Bioactive glass composite biological tissue repairing material and preparation method thereof

A technology of bioactive glass and repair material, applied in the field of bioactive glass composite biological tissue repair material and its preparation, can solve the problems of poor mechanical properties, poor drug adhesion, etc., achieve low immunogenicity, slow degradation rate, increase ratio The effect of surface area

Inactive Publication Date: 2017-09-15
WUHU YANGZHAN NEW MATERIAL TECH SERVICE CO LTD
View PDF6 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, due to the existence of amorphous silicon framework, bioglass still presents an amorphous form, with poor mechanical properties and poor drug adhesion.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Bioactive glass composite biological tissue repairing material and preparation method thereof
  • Bioactive glass composite biological tissue repairing material and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A bioactive glass composite biological tissue repair material, which is composed of the following raw materials in mass percentage: 35% of bioactive glass precursor solution, 35% of tetrahydrofuran, 10% of silk protein solution, 10% of silk protein nanofiber solution, nimesulide 3 %, Polyglycolide 3%, Green Tea Extract 2%, Sodium Hyaluronate 1%, Allantoin 1%.

[0018] The bioactive glass precursor solution is prepared by the following method: 4g P123 is dissolved in 60g ethanol, after fully stirring, 6.7g ethyl silicate, 0.73g triethyl phosphate, 1.4g Ca(NO 3 ) 2 4H 2 0. 1g of 0.5M hydrochloric acid solution; the mixed solution was stirred at room temperature for 24 hours and left to stand. When the solution was a viscous solution, the bioactive glass precursor solution was obtained.

[0019] The silk protein solution is prepared by the following method: heat 2L of deionized water to boiling, add 4g of sodium carbonate and 5g of silkworm raw silk, boil for 30min, clea...

Embodiment 2

[0024] A bioactive glass composite biological tissue repair material, which is composed of the following raw materials in mass percentage: 45% of bioactive glass precursor solution, 35% of tetrahydrofuran, 5% of silk protein solution, 5% of silk protein nanofiber solution, and 3% of nimesulide %, Polyglycolide 3%, Green Tea Extract 2%, Sodium Hyaluronate 1%, Allantoin 1%.

[0025] The bioactive glass precursor solution is prepared by the following method: 4g P123 is dissolved in 60g ethanol, after fully stirring, 6.7g ethyl silicate, 0.73g triethyl phosphate, 1.4g Ca(NO 3 ) 2 4H 2 0. 1g of 0.5M hydrochloric acid solution; the mixed solution was stirred at room temperature for 24 hours and left to stand. When the solution was a viscous solution, the bioactive glass precursor solution was obtained.

[0026] The silk protein solution is prepared by the following method: heat 2L of deionized water to boiling, add 4g of sodium carbonate and 5g of silkworm raw silk, boil for 30min...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to a bioactive glass composite biological tissue repairing material and a preparation method thereof, and belongs to the field of a composite biological material. The bioactive glass composite biological tissue repairing material consists of the following raw materials in percentage by mass: 35 to 45 percent of a bioactive glass precursor solution, 35 to 45 percent of tetrahydrofuran, 5 to 10 percent of a fibroin solution, 5 to 10 percent of a fibroin nano-fiber solution, 2 to 3 percent of nimesulide, 2 to 3 percent of polyglycollide, 1 to 2 percent of a green tea extract, 1 to 2 percent of sodium hyaluronate and 1 to 2 percent of allantoin. The bioactive glass composite biological tissue repairing material prepared by the method has high mechanical property and excellent medicinal adhesiveness.

Description

technical field [0001] The invention belongs to the field of composite biological materials, in particular to a bioactive glass composite biological tissue repair material and a preparation method thereof. Background technique [0002] With the transformation and upgrading of the textile industry, traditional textiles represented by fiber products are gradually developing towards high-tech textile biomedical materials. At present, my country's medical textiles are mainly non-implanted materials for health care, health care, protective products and medical dressing textile materials. High-end biomedical textiles such as artificial kidneys, artificial hearts, artificial lungs, artificial bones, and artificial skins are almost dependent on imports. Since its discovery in 1971, people have paid more attention to the influence of glass components on biological activity. The rise of nanotechnology has made people realize that structure also has an important impact on biological a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61L27/36A61L27/22A61L27/20A61L27/18A61L27/10A61L27/50A61L27/54A61L27/56
CPCA61L27/10A61L27/18A61L27/20A61L27/227A61L27/3637A61L27/50A61L27/54A61L27/56A61L2300/204A61L2300/236A61L2300/30A61L2300/412C08L5/08C08L67/04
Inventor 张春松吴长应
Owner WUHU YANGZHAN NEW MATERIAL TECH SERVICE CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com