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Nanocarrier coated sorbic acid-tea polyphenol composite nanoparticles

A composite nanoparticle and nanocarrier technology, which is applied in the field of composite nanoparticle preparation, can solve the problems of poor stability, oxidation, polymerization, condensation, and low bioavailability of tea polyphenol powder, and achieve good fresh-keeping function, reasonable setting, and prevention The effect of cardiovascular and cerebrovascular diseases

Inactive Publication Date: 2017-10-03
JIANGSU TIANCHENG BIOCHEM PROD
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  • Abstract
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Problems solved by technology

However, the stability of tea polyphenol powder is poor, and it is easy to undergo reactions such as oxidation, polymerization, and condensation under conditions such as humidity, sunlight, and high temperature.
The bioavailability of catechins and other active substances in tea polyphenols is not high in the unprotected state. When taken directly as health care medicines, the structure of gastrointestinal digestion will be destroyed, affecting its health care effect

Method used

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Experimental program
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Embodiment Construction

[0013] The technical scheme that this specific embodiment adopts is: its preparation process is as follows:

[0014] 1. Preparation and screening of suitable nanocarriers: Phytosterols, gelatin, chitosan, and lycopene were used as nanocarrier preparation materials, and by changing the concentration of target molecules, the type and content of initiators during the synthesis of nanocarriers , assembly mode, and stirring speed of the microemulsion system to prepare nanocarriers with different shapes and particle sizes, and screen out nanocarriers with strong loading capacity and good biocompatibility;

[0015] 2. Synthesize sorbic acid and tea polyphenols by emulsion polymerization, molecular self-assembly, template polymerization or emulsification dispersion to prepare composite nanoparticles;

[0016] 3. The functional response performance test was carried out on the prepared composite nanoparticles: the content of free sorbic acid was measured by membrane separation method, t...

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Abstract

A nano-carrier-coated sorbic acid-tea polyphenol composite nanoparticle, the invention relates to the technical field of composite nano-particle preparation; one, prepare and screen a suitable nano-carrier; two, use sorbic acid and tea polyphenol by emulsion polymerization, Composite nanoparticles are prepared by molecular self-assembly method, template polymerization method or emulsification dispersion method; 3. The functional response performance test of the prepared composite nanoparticles is carried out. Not only has the antiseptic properties of sorbic acid molecules, endows beverages with a good fresh-keeping function, but also maintains the advantages of tea polyphenols such as anti-tumor, anti-radiation, anti-oxidation, and prevention of cardiovascular and cerebrovascular diseases.

Description

technical field [0001] The invention relates to the technical field of composite nanoparticle preparation, in particular to a nanocarrier-based coated sorbic acid-tea polyphenol composite nanoparticle. Background technique [0002] Nanocarriers (phytosterols, gelatin, chitosan, lycopene) have not only the characteristics of the drug itself, but also good adsorption properties, sustained release properties, dissolution properties and targeting properties due to their small molecule chemical characteristics. Loading functional products such as sorbic acid-tea polyphenols on the surface of nanocarriers can enhance the biological activity of the products and realize the targeted delivery of active substances. The project involves the controllable synthesis and modification of various nanocarriers, and screening out nanocarriers with strong loading capacity and good biocompatibility. [0003] Sorbic acid and its salts have a good inhibitory effect on the growth of mold and yeast...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L2/52A23L2/44A23L33/10
CPCA23L2/52A23L2/44A23V2002/00
Inventor 陈飞王小清崔惠忠陶建峰刘长兵蒋玉林
Owner JIANGSU TIANCHENG BIOCHEM PROD
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