Preparation method of multiple-mineral-matter vitamin preparation

A vitamin preparation and mineral technology, which is applied in the field of nutritional health food, can solve the problems of easy appearance of black spots, reduced content, and impact on product quality, etc., and achieves promotion of human metabolism, enhanced stability, and good coating effect. Effect

Active Publication Date: 2017-10-20
WUHAN VITAL PHARMA
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Problems solved by technology

Among them, vitamin D is a very unique member of all biologically active substances. It has multiple functions, not only plays an important role in the metabolism of calcium and phosphorus in the human body and bone calcification, but also has a wide range of effects on various tissue cells in the whole body. Both are closely related, but due to the influence of vitamin D on light, air, humidity and other substances in the product, in the production process and product storage, the products made by using conventional preparation methods, vitamin D is affected by the above factors, and the content of vitamin D is greatly increased. Reduce the intake of vitamin D, so that people's vitamin D intake is insufficient to achieve the desired effect of nutritional supplements, and the air and humidity will affect the trace element manganese and other substances in the product, and it is very easy to convert divalent manganese into manganese dioxide. The manganese element is affected by the above factors during the storage process of the finished product, resulting in black spots on the appearance of the product, and the quality of the product is affected in different ways, which is not conducive to human body absorption

Method used

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  • Preparation method of multiple-mineral-matter vitamin preparation
  • Preparation method of multiple-mineral-matter vitamin preparation

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preparation example Construction

[0019] A preparation method of multi-mineral vitamin preparation, comprising the following steps:

[0020] 1) Vitamin D pretreatment: mix microcrystalline cellulose and 3% HPMC solution to make 10-mesh pellets, dilute the vitamin D oil solution with 95% alcohol 100:1 and spray on the pellets until the pellets fully absorb the vitamin D to saturated state, dry for use;

[0021] 2) Preparation of vitamin D-embedded granules: use purified water as solvent, mix coating agent A with water evenly to make a coating solution with a solid content of 15%, coat the pellets that have absorbed vitamin D, and dry until use;

[0022] 3) Pretreatment of divalent manganese ions: the divalent manganese is manganese sulfate, after mixing microcrystalline cellulose and manganese sulfate in a mass ratio of 2:1, mixture A is obtained, and further mixture A and binder 3% HPMC The solutions were mixed to make 10-mesh pellets, which were dried for later use;

[0023] 4) Preparation of divalent mang...

Embodiment 1

[0032] A multi-mineral vitamin preparation and a preparation method thereof, the specific preparation steps are as follows:

[0033] 1) Vitamin D pretreatment: Mix microcrystalline cellulose and 3% HPMC solution at a mass ratio of 3.5:1 to make 10-mesh pellets, dilute the vitamin D oil solution with 95% alcohol 100:1 and spray on the pellets After the pellets fully absorb vitamin D to a saturated state, dry it for use;

[0034] 2) Preparation of vitamin D embedding granules: use purified water as a solvent, mix coating agent A and water evenly to make a coating solution with a solid content of 15%, at an air inlet temperature of 60°C, and a tablet bed temperature of 38-42 Under the conditions of ℃, atomization pressure 2.0bar, coating pan speed 5rpm, and coating solution flow rate 80-100g / min, the vitamin D-absorbed pellets were coated and dried for use. The composition of coating agent A is shown in Table 1 Shown:

[0035] The composition of table 1 coating agent A

[0036...

Embodiment 2

[0044] A multi-mineral vitamin preparation and a preparation method thereof, the specific preparation steps are as follows:

[0045] 1) Vitamin D pretreatment: Mix microcrystalline cellulose and 3% HPMC solution at a mass ratio of 3.8:1 to make 10-mesh pellets, dilute the vitamin D oil solution with 95% alcohol 100:1 and spray on the pellets After the pellets fully absorb vitamin D to a saturated state, dry it for use;

[0046] 2) Preparation of vitamin D embedding granules: use purified water as a solvent, mix coating agent A and water evenly to make a coating solution with a solid content of 15%, at an air inlet temperature of 60°C, and a tablet bed temperature of 38-42 Under the conditions of ℃, atomization pressure 2.0bar, coating pan speed 5rpm, and coating solution flow rate 80-100g / min, the vitamin D-absorbed pellets were coated and dried for use. The composition of coating agent A is shown in Table 1 Shown:

[0047] The composition of table 1 coating agent A

[0048...

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Abstract

The invention relates to a preparation method of a multiple-mineral-matter vitamin preparation, and belongs to the field of nutritional health-care food. The method comprises concrete steps of: pre-treating vitamin D, preparing vitamin-D-embedded particles, pre-treating divalent manganese ions, preparing divalent-manganese-ion-embedded particles, pre-treating mineral matter elements, and synthesizing the preparation. According to the prepared multiple mineral matter vitamin preparation, vitamin D and divalent manganese ions are effectively isolated from other multiple mineral matter elements that are added in the preparation. Interference of the external environment to the preparation is prevented, stability of the preparation is effectively improved, and the medicine performance is fully developed. Through addition of multiple mineral matter elements, intake of adequate necessary nutritional elements by the human body is ensured.

Description

technical field [0001] The invention belongs to the field of nutrition and health food, and in particular relates to a preparation method of a multi-mineral vitamin preparation. Background technique [0002] With the development of science and technology and the improvement of people's health awareness, it has become a new trend to take the initiative to supplement nutritional and health food every day to supplement three meals a day for insufficient nutrients or to prevent certain diseases. A large number of studies have shown that vitamins, minerals and nutrient supplements with them as the main components can effectively prevent diseases. An important component of coenzymes and hormones. When deficient, it can lead to metabolic disorders and cause various diseases. [0003] As a nutritional supplement, multi-mineral vitamin preparations contain a variety of mineral elements and vitamins, which can supplement the deficiency of vitamins and trace and macro elements in the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L33/155A23L33/16A23L33/115A23P10/35
CPCA23L33/115A23L33/155A23L33/16A23P10/35A23V2002/00A23V2200/30A23V2200/224A23V2250/1612A23V2250/1578A23V2250/1592A23V2250/1642A23V2250/1626A23V2250/161A23V2250/1614A23V2250/1624A23V2250/1634A23V2250/18A23V2250/1628A23V2250/51084A23V2250/51086A23V2250/71A23V2300/10
Inventor 郭卫平吴烨桓
Owner WUHAN VITAL PHARMA
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