Preparation method of low-sugar type ferrum-folic acid tablets

A technology of iron folic acid and sugar form, which is applied in the field of preparation of low-sugar iron folic acid tablets, which can solve the problems of poor taste, difficulty in absorption, and high sugar content in iron folic acid tablets, and achieve the effects of reasonable formula, unbreakable and easy disintegration

Inactive Publication Date: 2017-11-17
安徽康博特保健食品有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the current iron folic acid tablets have high sugar content, poor taste, and

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] A kind of preparation method of low-sugar type iron folic acid tablet that the present invention proposes, comprises the following steps:

[0018] S1. Mix ferrous fumarate, ferrous gluconate, folic acid compound and edible corn starch evenly to obtain a premix;

[0019] S2. Mix mint, sodium carboxymethyl starch, maltodextrin, and microcrystalline cellulose evenly, add premix and magnesium stearate, mix evenly, and press into tablets to obtain low-sugar iron folic acid tablets.

Embodiment 2

[0021] A kind of preparation method of low-sugar type iron folic acid tablet that the present invention proposes, comprises the following steps:

[0022] S1. Mix 30 parts of ferrous fumarate, 15 parts of ferrous gluconate, 2 parts of folic acid compound, and 100 parts of edible corn starch in parts by weight to obtain a premix;

[0023] S2. Mix 1 part of mint, 4 parts of sodium carboxymethyl starch, 1 part of maltodextrin, and 4 parts of microcrystalline cellulose in parts by weight, add 120 parts of premix and 3 parts of magnesium stearate, mix uniformly, press Tablets to get low-sugar iron folic acid tablets.

Embodiment 3

[0025] A kind of preparation method of low-sugar type iron folic acid tablet that the present invention proposes, comprises the following steps:

[0026] S1. Mix 40 parts of ferrous fumarate, 5 parts of ferrous gluconate, 8 parts of folic acid compound, and 60 parts of edible corn starch in parts by weight to obtain a premix;

[0027] The folic acid complex is prepared by the following process: mix folic acid, cholesterol, Tween 80, and egg yolk lecithin evenly, add absolute ethanol to stir, add phosphate buffer, continue stirring, evaporate to remove ethanol, cool, add carboxymethyl cellulose Sodium, homogeneously processed to obtain folic acid complex;

[0028] S2. Mix 4 parts of peppermint, 2 parts of sodium carboxymethyl starch, 2 parts of maltodextrin, and 2 parts of microcrystalline cellulose in parts by weight, add 140 parts of premix and 1 part of magnesium stearate, mix evenly, and press Tablets to get low-sugar iron folic acid tablets.

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PUM

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Abstract

The invention discloses a preparation method of low-sugar type ferrum-folic acid tablets. The preparation method comprises the following steps of uniformly mixing ferrous fumarate with ferrous gluconate, a folic acid compound and edible corn starch so as to obtain a premix; and uniformly mixing mint with sodium carboxymethyl starch, maltodextrin and microcrystalline cellulose, adding the premix and magnesium stearate, performing uniform mixing, and performing tabletting so as to obtain the low-sugar type ferrum-folic acid tablets. The folic acid compound is prepared through the following technology: uniformly mixing folic acid with cholesterol, Tween 80 and egg yolk lecithin, adding anhydrous ethanol, performing stirring, adding a phosphate buffer solution, continuing performing stirring, performing evaporation to remove ethanol, performing cooling, adding sodium carboxymethyl cellulose, and performing homogenizing treatment so as to obtain the folic acid compound. The obtained ferrum-folic acid tablets are good in mouth feel, extremely low in sugar content, easy to disintegrate after entering the intestines and the stomach, and easy to digest and absorb by human bodies, can effectively complement folic acid and ferrum, and have the effects of being fresh in breath and promoting the health of oral cavities after being eaten, and the defects of similar products in the market at present are overcome.

Description

technical field [0001] The invention relates to the technical field of health care products, in particular to a preparation method of low-sugar iron folic acid tablets. Background technique [0002] Iron folic acid tablet is a kind of nutritional supplement, suitable for pregnant women and pregnant women. Folic acid can promote the development of nerve cells and brain cells in infants. Lack of folic acid can easily lead to fetal neural tube development defects, and increase the risk of split brain and anencephaly. Folic acid supplementation is necessary in the pre-pregnancy and early stages, which can help prevent the occurrence of fetal neural tube defects. Folic acid can promote the absorption of iron and prevent the unsuitable phenomenon of single iron supplementation. However, the current iron folic acid tablets have high sugar content, poor taste, and are difficult to absorb after entering the stomach, which needs to be solved urgently. Contents of the invention [0...

Claims

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Application Information

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IPC IPC(8): A23L33/15A23L33/165
CPCA23L33/15A23L33/165A23V2002/00A23V2250/7056A23V2250/1592
Inventor 徐涛
Owner 安徽康博特保健食品有限公司
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