Wheat germ fermented flavonoid extract, preparation method of wheat germ fermented flavonoid extract, and application of wheat germ fermented flavonoid extract in animal raising

Abstract

The invention provides a wheat germ fermented flavonoid extract, a preparation method of the wheat germ fermented flavonoid extract, and an application of the wheat germ fermented flavonoid extract in animal raising. The wheat germ fermented flavonoid extract is extracted from wheat germ fermented supernatant liquid; and preferably, the wheat germ fermented supernatant liquid is subjected to chromatographic purification by virtue of a non-polar or weakly polar macroporous resin column to obtain the wheat germ fermented flavonoid extract, wherein 1g of dry matter contains 2.5-5.8mg of total flavonoids. The wheat germ fermented flavonoid extract can serve as a substituted antibiotic feed additive for preparing production feed or premixed feed, and is capable of preventing and treating animal diseases, improving the yield of raised animals, improving the antibody titer of vaccinated animals, prolonging the effective titer in antibody blood and enhancing the immunity of the vaccinated animals to diseases.

Description

technical field [0001] The invention provides a wheat germ fermented flavonoid extract, a preparation method thereof and an application in animal feeding. Background technique [0002] In 1946, Moore et al. published a paper for the first time discussing that adding antibiotics to broiler feed can improve production performance. Since then, adding antibiotics to feed to promote animal growth has become popular. Antibiotics were the first to become animal feed additives. The invention and application of antibiotics is one of the greatest inventions of the 20th century. The use of antibiotics has laid the foundation for large-scale farming, but the abuse of antibiotics has caused serious side effects, and the emergence of bacterial resistance has seriously threatened human beings. and animal safety. In order to prevent and treat diseases, a large number of antibiotics are widely used in livestock / poultry and fish feeds. Drug residues in meat, eggs and dairy products have alr...

AI Technical Summary

Problems solved by technology

The pig industry in the European Union mostly uses compound acids to replace antibiotics, but the disadvantages are that the dosage is large and the cost is high

However, due to the complexity of the product and the difficulty of research, it is currently unsatisfactory in terms of industrialization

Effective microecological preparations need to answer two questions: First, can it be proved that the isolated beneficial microorganisms can reach the intestinal tract through the stomach and colonize the intestinal tract? Second, can it be proved that such beneficial microorganisms can inhibit / resist / even kill pathogenic microorganisms? In addition, problems such as the dosage form of live bacteria and the preservation of effective concentration of live bacteria have always plagued the industrialization of microecological preparations

The quality of Chinese herbal medicine feed additive products on the market is mixed, and there are the following problems: ①The compatibility and mechanism of Chinese herbal medicines are not very clear, Chinese herbal medicines are not completely non-toxic, side effects, improper use, toxic side effects and even fatal

2,6-DMBQ has a strong anticancer effect in vitro, but in vivo experiments have failed to confirm that the compound has immunomodulatory and anticancer effects

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