Novel medicine balloon and preparation method thereof

A balloon and drug technology, applied in the field of medical devices, can solve the problems of vascular restenosis, limit the development of PCI, etc., achieve the effects of prolonging the continuous filling time, good wall-attachment performance, and avoiding drug loss

Pending Publication Date: 2018-01-09
SHANGHAI XINZHI MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

After treatment, 5-60% of the patients will have vascular restenosis ...

Method used

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  • Novel medicine balloon and preparation method thereof
  • Novel medicine balloon and preparation method thereof
  • Novel medicine balloon and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0041] figure 1 A specific embodiment of the novel drug balloon involved in the present invention is shown. In this embodiment, the novel drug balloon includes a balloon body 1 . The surface of the balloon body 1 is covered with medicine 2 for 360°. The balloon body 1 has three flaps 3 . The number of flaps 3 is not limited to three in the present invention. In the inflated state, the cross section of the balloon body 1 shows that a concave structure 4 is arranged between adjacent flaps. The function of the concave structure 4 is to make the new drug balloon not completely block the blood flow even in the filled state, thereby prolonging the continuous filling time and providing more time for drug release, thereby achieving a better effect. In the folded state, the medicine 2 on the inner surface of the flap 3 is folded inside, so it does not contact the blood vessel wall, thereby ensuring that this part of the medicine 2 will not be lost when the balloon body 1 passes thr...

Embodiment 2

[0045] In this embodiment, the development line in Embodiment 1 is replaced with the annular development elements provided at the proximal and distal ends of the balloon body, and the rest are the same as in Embodiment 1.

Embodiment 3

[0047] In the inflated state, the surface of the cross section of the balloon body is provided with a concave structure, which facilitates the passage of blood. Different from Embodiment 1, the depression is not limited to the depression between the flaps. The rest are the same as in Example 1.

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Abstract

The invention discloses a novel drug balloon, comprising a balloon body, the balloon body has a folded state and a filled state; in the filled state, the balloon body presents a concave structure, so that blood can flow through the concave structure Balloon body. The present invention also discloses a preparation method of the above-mentioned novel medicine balloon, which involves covering the medicine on the balloon body through iopromide by means of leaching and/or ultrasonic spraying. The concave structure of the novel drug balloon involved in the present invention ensures smooth blood flow, thereby prolonging the working time and making the treatment effect better.

Description

technical field [0001] The invention belongs to the field of medical devices, and in particular relates to a novel drug balloon and a preparation method thereof. Background technique [0002] Cardiovascular stenosis is one of the main causes of coronary heart disease. Percutaneous Coronary Intervention (PCI) is an important means of treating cardiovascular stenosis. With the increase in the number of stents used, the problem of in-stent restenosis (ISR) is becoming more and more serious. After treatment, 5-60% of the patients will have vascular restenosis in the short and medium term, which seriously limits the development of PCI. [0003] In recent years, a new technology to prevent restenosis of blood vessels after interventional therapy-drug balloons has emerged. It is to apply anti-intimal hyperplasia drugs on the surface of the balloon. When the balloon reaches the wall of the diseased vessel, it is stretched and filled, and contacts the intima of the vessel wall, an...

Claims

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Application Information

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IPC IPC(8): A61M29/02A61M25/10A61M25/01A61K31/337A61K31/436A61P35/00
Inventor 盛卫文朱平
Owner SHANGHAI XINZHI MEDICAL TECH CO LTD
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