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Method for extracting Tremella polysaccharide from acid buffer solution

An acid buffer solution and tremella polysaccharide technology, applied in the field of plant polysaccharide extraction, can solve the problems of enzyme reagent cost, filtration difficulty, high energy consumption, etc., and achieve the effects of low cost, improved extraction rate, and low energy consumption

Active Publication Date: 2020-05-08
FUZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

If you add auxiliary equipment such as ultrasonic generator, microwave reaction system or pressure cooker to extract tremella polysaccharide, the cost of additional equipment investment will be increased, and the energy consumption will be high.
Although the enzyme extraction method is relatively mild, it will face problems such as increased viscosity of the extract, difficulty in filtration, increased impurities such as proteins, and the cost of enzyme reagents during the extraction process.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] The commercially available white fungus is dried, crushed and passed through a 90-mesh sieve. After adding 40ml of citric acid-sodium citrate buffer solution with a pH of 3.0 to 1g of white fungus powder, place it in a hot water bath at 100°C for leaching. After 5 hours, centrifuge the leaching material at a speed of 8000rpm for 8min to remove the residue. Add 4 times the volume of 90% ethanol solution to the supernatant, precipitate for 12 hours, centrifuge at 10,000 rpm for 8 minutes, remove the supernatant, and obtain Tremella polysaccharide precipitate.

[0034] The control test is to replace the citric acid-sodium citrate buffer solution with water as the extraction solvent, and the method is the same as above.

[0035] All the obtained white fungus polysaccharide precipitates were dissolved in 20ml of water, and the polysaccharide content in the solution was measured by the phenol-sulfuric acid method to be 15.79mg / ml. The calculated polysaccharide quality in the ...

Embodiment 2

[0037]The commercially available white fungus is dried, crushed and passed through a 80-mesh sieve. After adding 40ml of citric acid-sodium citrate buffer solution with a pH of 3.0 to 1g of white fungus powder, place it in a hot water bath at 100°C for leaching. After 4 hours, centrifuge the leaching material at a speed of 7500rpm for 5min to remove the residue. Add 4.5 times volume of 95% ethanol solution to the supernatant, precipitate for 11 hours, centrifuge at 11,000 rpm for 6 minutes, remove the supernatant, and obtain Tremella polysaccharide precipitate.

[0038] The control test is to replace the citric acid-sodium citrate buffer solution with water as the extraction solvent, and the method is the same as above.

[0039] All the tremella polysaccharide precipitates obtained were dissolved in 20ml of water, and the polysaccharide content in the solution was measured by the phenol-sulfuric acid method to be 14.35mg / ml. The calculated polysaccharide quality in the polysac...

Embodiment 3

[0041] The commercially available white fungus is dried, crushed and passed through a 80-mesh sieve. After adding 60ml of citric acid-sodium citrate buffer solution with a pH of 3.0 to 1g of white fungus powder, place it in a hot water bath at 80°C for leaching. After 5 hours, centrifuge the leaching material at a speed of 9000rpm for 7min to remove the residue. Add four times the volume of ethanol solution with a volume concentration of 90% to the supernatant, precipitate for 10 hours, centrifuge at 10,000 rpm for 10 minutes, remove the supernatant, and obtain Tremella polysaccharide precipitate.

[0042] The control test is to replace the citric acid-sodium citrate buffer solution with water as the extraction solvent, and the method is the same as above.

[0043] All the obtained tremella polysaccharide precipitates were dissolved in 20ml of water, and the polysaccharide content in the solution was measured by the phenol-sulfuric acid method to be 5.10 mg / ml. The calculated ...

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Abstract

The invention provides a method for extracting tremella polysaccharide from an acid buffer solution. The method comprises the following steps: leaching tremella powder by virtue of an acid buffer solution under a heating condition, so as to obtain leached material liquid; carrying out solid-liquid separation on the leached material liquid, so as to obtain a liquid component, wherein the liquid component contains tremella polysaccharide; and carrying out alcohol precipitation on the liquid component, so as to obtain a precipitate, namely tremella polysaccharide. The method has the beneficial effects that the extraction rate of tremella polysaccharide can reach 31.57%, is 3-4 times of that of a traditional water extraction method and is greatly increased.

Description

technical field [0001] The invention belongs to the technical field of extracting plant polysaccharides, and in particular relates to a method for extracting tremella polysaccharides with an acidic buffer solution. Background technique [0002] Tremella, also known as white fungus, is a higher fungus that has the functions of nourishing yin and moistening the lungs, nourishing qi and blood. Tremella polysaccharide is the main active ingredient of Tremella, which is an acidic heteropolysaccharide derived from Tremella ( Tremella fuciformis Berk) fruiting body, its main chain structure is mannan linked by α-(1→3) glycosidic bonds, and the branch chain is composed of glucuronic acid and xylose. Tremella polysaccharide has the functions of regulating immune function, anti-thrombosis, prolonging blood clotting time, lowering blood sugar and blood fat, assisting tumor suppression, delaying aging and anti-radiation. Japanese scholars first extracted polysaccharides from Tremella...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08B37/00
Inventor 杨捷程振林娟叶秀云
Owner FUZHOU UNIV