Unlock instant, AI-driven research and patent intelligence for your innovation.

Diarrhea-resisting enteral nutrition composition

A technology of composition and enteral nutrition, applied in the direction of drug combination, food science, plant raw materials, etc.

Inactive Publication Date: 2018-01-23
江苏西宏生物医药有限公司
View PDF5 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] However, the above-mentioned nausea, vomiting or gastrointestinal adverse reactions such as abdominal distension, abdominal pain, and diarrhea still exist to a certain extent in the prior art, and there is still a lot of room for improvement

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Enteral Nutrition Prescription:

[0038] Pectin 3% (g / ml), Bifidobacterium bifidum 2 billion (colony forming units / ml),

[0039] Among them, every 100ml of nutritional supplements contains: protein (1-5g) 3.4g, fat (1-5g) 3.2g, saturated fatty acid (0.1-2g) 0.5g, essential fatty acid (1-5g) 1.9g carbohydrate (2 ~25g) 12g (monosaccharide (1~5g) 3.5g); dietary fiber (1~5g) 1.5g, water (to 100ml) 89ml, vitamin A60mg, vitamin D30.35mg, vitamin E0.75mg, vitamin K15mg , vitamin B10.1mg, vitamin B20.13mg, nicotinamide 0.9mg, vitamin B60.12mg, vitamin B120.2mg, pantothenic acid 0.35mg, biotin 10mg, folic acid 10mg, vitamin C4.5mg, choline 20mg, appropriate amount of water (plus to the full amount of 100ml). The pH of the solution is 6.4-6.8, and the calcium ion does not exceed 0.1PPM.

[0040] Wherein, pectin in embodiment 1-1,2,3,4,5,6 is respectively:

[0041] Low methoxyl pectin with a degree of esterification (DE) of 10% and pectin with a molecular weight of 30,000,

...

Embodiment 2

[0054] Enteral nutrient prescription: 2% (g / ml) pectin, Escherichia coli 5 billion colony-forming units / ml,

[0055] Among them, every 100ml of nutritional supplements contains: protein (1-5g) 3.4g, fat (1-5g) 3.2g, saturated fatty acid (0.1-2g) 0.5g, essential fatty acid (1-5g) 1.9g carbohydrate (2 ~25g) 12g (monosaccharide (1~5g) 3.5g); dietary fiber (1~5g) 1.5g, appropriate amount of water (add to the full amount of 100ml),

[0056] Wherein, pectin in embodiment 2-1, 2, 3 is respectively:

[0057] Low methoxy pectin with a degree of esterification (DE) of 7% and pectin with a molecular weight of 12000,

[0058] Low methoxy pectin with a degree of esterification (DE) of 15% and pectin with a molecular weight of 12000,

[0059] Low methoxyl pectin with a degree of esterification (DE) of 7% and pectin with a molecular weight of 100,000. The pH of the solution is 6.4-6.8, and the calcium ion does not exceed 0.1PPM.

Embodiment 3

[0067] Enteral nutrient prescription: 0.5% (g / ml) pectin, 50 billion colony-forming units / ml of Enterococcus faecium,

[0068] Among them, every 100ml of nutritional supplements contains: protein (1-5g) 3.4g, fat (1-5g) 3.2g, saturated fatty acid (0.1-2g) 0.5g, essential fatty acid (1-5g) 1.9g carbohydrate (2 ~25g) 12g (monosaccharide (1~5g) 3.5g); dietary fiber (1~5g) 1.5g, appropriate amount of water (add to the full amount of 100ml),

[0069] Wherein, pectin in embodiment 3-1, 2, 3 is respectively:

[0070] Low methoxyl pectin with a degree of esterification (DE) of 15% and pectin with a molecular weight of 22000,

[0071] Low methoxyl pectin with a degree of esterification (DE) of 30% and pectin with a molecular weight of 22000,

[0072] Low methoxy pectin with a degree of esterification (DE) of 15% and pectin with a molecular weight of 150,000. The pH of the solution is 6.4-6.8, and the calcium ion does not exceed 0.1PPM.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Viscosityaaaaaaaaaa
Login to View More

Abstract

The invention provides a diarrhea-resisting enteral nutrition composition, and discloses a liquid enteral nutrition agent capable of reducing the occurrence rate of abdominal distension. The enteral nutrition agent contains one or more pectins with the esterification degree being 5-30 % and the viscosity-average molecular weight being 10000-150000, one or more probiotics, and one or more nutritioncomponents, wherein the content of calcium ions in the enteral nutrition composition does not exceed 0.1PPM. With the enteral nutrition composition, the adverse reactions (such as diarrhea, abdominaldistension and emesis), especially diarrhea of the gastrointestinal tract can be obviously reduced.

Description

technical field [0001] The present invention relates to an enteral nutritional composition, and more particularly, to an enteral with a reduced incidence of gastrointestinal adverse reactions, especially diarrhea. Background technique [0002] Enteral nutrition refers to inserting a feeding tube into the stomach or intestines through one side of the nasal cavity, oral cavity or gastroenterostomy, and dripping elemental diet or liquid diet from the tube to ensure that the patient takes in enough protein and Therapeutic method of heat. Enteral nutrition refers to the general term for various products used for clinical enteral nutrition support. Reasonable nutritional support can enhance the body's resistance, promote the improvement of the condition, and even prolong the patient's life. However, there are also many unavoidable deficiencies in the clinical application of enteral nutrition, mainly including gastrointestinal reactions, nausea, vomiting or abdominal distension, a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K35/741A61K36/064A61K36/062A61K35/745A61K35/742A61K35/744A61K35/747A61P1/08A61P1/12A61P1/00A61P1/14A23L33/135A23L33/14A23L29/231A61K31/732
Inventor 王志强谭建雄李用琳徐增松
Owner 江苏西宏生物医药有限公司