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Diarrhea-resisting enteral nutrition composition

A composition, enteral nutrition technology, used in drug combinations, resistance to vector-borne diseases, plant raw materials, etc.

Inactive Publication Date: 2018-01-23
江苏西宏生物医药有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0010] However, the above-mentioned nausea, vomiting or gastrointestinal adverse reactions such as abdominal distension, abdominal pain, and diarrhea still exist to a certain extent in the prior art, and there is still a lot of room for improvement

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Enteral Nutrition Prescription:

[0038] Pectin 3% (g / ml), Bifidobacterium bifidum 2 billion (colony forming units / ml), of which, each 100ml containing nutritional agent contains: protein (1-5g) 3.4g, fat (1-5g) 3.2 g, saturated fatty acid (0.1~2g) 0.5g, essential fatty acid (1~5g) 1.9g carbohydrate (2~25g) 12g (monosaccharide (1~5g) 3.5g); dietary fiber (1~5g) 1.5g , water (up to 100ml) 89ml, vitamin A60mg, vitamin D30.35mg, vitamin E0.75mg, vitamin K15mg, vitamin B10.1mg, vitamin B20.13mg, nicotinamide 0.9mg, vitamin B60.12mg, vitamin B120.2mg , 0.35mg of pantothenic acid, 10mg of biotin, 10mg of folic acid, 4.5mg of vitamin C, 20mg of choline, appropriate amount of water (add to the full amount of 100ml). The pH of the solution is 6.4-6.8, and the calcium ion does not exceed 0.1PPM.

[0039] Wherein, pectin in embodiment 1-1,2,3,4,5,6 is respectively:

[0040] Low methoxyl pectin with a degree of esterification (DE) of 10% and pectin with a molecular weight of 30,...

Embodiment 2

[0048] Enteral nutrition prescription: 2% (g / ml) pectin, Escherichia coli 5 billion colony-forming units / ml, among them, each 100ml of nutritional supplements contains: protein (1 ~ 5g) 3.4g, fat (1 ~5g) 3.2g, saturated fatty acid (0.1~2g) 0.5g, essential fatty acid (1~5g) 1.9g carbohydrate (2~25g) 12g (monosaccharide (1~5g) 3.5g); dietary fiber (1~5g) 5g) 1.5g, an appropriate amount of water (adding to the full amount of 100ml), wherein, the pectin in Examples 2-1, 2, and 3 is respectively: the degree of esterification (DE) is 7% low-methoxyl pectin and the molecular weight is 12000 pectin, low methoxyl pectin with a degree of esterification (DE) of 15% and pectin with a molecular weight of 12000, low methoxyl pectin with a degree of esterification (DE) of 7% and a pectin. The pH of the solution is 6.4-6.8, and the calcium ion does not exceed 0.1PPM.

Embodiment 3

[0056] Enteral nutrient prescription: 0.5% (g / ml) pectin, Enterococcus faecium 50 billion colony-forming units / ml, among them, each 100ml of nutrient contains: protein (1-5g) 3.4g, fat (1-5g ) 3.2g, saturated fatty acid (0.1~2g) 0.5g, essential fatty acid (1~5g) 1.9g carbohydrate (2~25g) 12g (monosaccharide (1~5g) 3.5g); dietary fiber (1~5g) 1.5g, an appropriate amount of water (up to 100ml in total), wherein the pectins in Examples 3-1, 2, and 3 are respectively: low-methoxyl pectin with a degree of esterification (DE) of 15% and pectin with a molecular weight of 22,000 Pectin, low methoxy pectin with a degree of esterification (DE) of 30% and pectin with a molecular weight of 22000, low methoxyl pectin with a degree of esterification (DE) of 15% and pectin with a molecular weight of 150000 . The pH of the solution is 6.4-6.8, and the calcium ion does not exceed 0.1PPM.

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Abstract

The invention provides a diarrhea-resisting enteral nutrition composition, and discloses a liquid enteral nutrition agent capable of reducing the occurrence rate of emesis. The enteral nutrition agentcontains one or more pectins with the esterification degree being 5-30 % and the viscosity-average molecular weight being 10000-150000, one or more probiotics, and one or more nutrition components, wherein the content of calcium ions in the enteral nutrition composition does not exceed 0.1PPM. With the enteral nutrition composition, the adverse reactions (such as diarrhea, abdominal distension and emesis), especially diarrhea of the gastrointestinal tract can be obviously reduced.

Description

technical field [0001] The present invention relates to an enteral nutrition composition, more specifically, relates to an enteral nutrition composition with reduced incidence of gastrointestinal adverse reactions, especially diarrhea. Background technique [0002] Enteral nutrition refers to inserting a feeding tube into the stomach or intestines through one side of the nasal cavity, oral cavity or gastroenterostomy, and dripping elemental diet or liquid diet from the tube to ensure that the patient takes in enough protein and Therapeutic method of heat. Enteral nutrition refers to the general term for various products used for clinical enteral nutrition support. Reasonable nutritional support can enhance the body's resistance, promote the improvement of the condition, and even prolong the patient's life. However, there are also many unavoidable deficiencies in the clinical application of enteral nutrition, mainly including gastrointestinal reactions, nausea, vomiting or a...

Claims

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Application Information

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IPC IPC(8): A61K35/741A61K36/064A61K36/062A61K35/745A61K35/742A61K35/744A61K35/747A61P1/08A61P1/12A61P1/00A61K31/715
CPCY02A50/30
Inventor 王志强谭建雄李用琳徐增松
Owner 江苏西宏生物医药有限公司