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Traditional Chinese veterinary medicine composition for treating swine enzootic pneumonia as well as preparation method and application thereof

A technology for swine asthma and a composition, applied in the field of traditional Chinese veterinary medicine, can solve problems such as lack of effective preparations and means, and achieve the effects of improving body immunity, reducing the number of administrations, and being less prone to recurrence.

Inactive Publication Date: 2018-02-27
广州和仕康生物技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, the prevention and treatment of swine asthma is still a weak link, and there is a lack of effective preparations and means. It is still a top priority to develop new drugs that are fast-acting, safe and effective, so as to adapt to the clinical treatment of breeding enterprises

Method used

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  • Traditional Chinese veterinary medicine composition for treating swine enzootic pneumonia as well as preparation method and application thereof
  • Traditional Chinese veterinary medicine composition for treating swine enzootic pneumonia as well as preparation method and application thereof
  • Traditional Chinese veterinary medicine composition for treating swine enzootic pneumonia as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0030] 1. Prescription composition:

[0031] 5kg of mulberry leaves, 20kg of chrysanthemums, 10kg of basil, 30kg of Houttuynia cordata, and 15kg of licorice.

[0032] 2. Preparation method:

[0033] (1) Take 20kg of chrysanthemums and 30kg of Houttuynia cordata, add water 8 times the weight of chrysanthemum and Houttuynia cordata, steam distill for 3 hours, collect volatile oil, dissolve with a small amount of ethanol, and obtain volatile oil ethanol solution, set aside; steam distillation The extract is filtered, and the filtrate and medicinal residues are used for subsequent use;

[0034] (2) Get 5 kg of mulberry leaves, 10 kg of mulberry leaves, and 15 kg of licorice, and after pulverization, add the dregs after extracting the volatile oil in step (1) to carry out water extraction, and then add 8 times the weight of mulberry leaves, radishes, and licorice. Water, reflux extraction twice, each time for 1.5 hours, the extract was filtered and concentrated; the concentrated ...

Embodiment 7

[0068] Embodiment 7: mouse acute toxicity test

[0069] 1. Purpose

[0070] Observe the acute toxic reaction of the Chinese veterinary drug composition prepared in Example 2 of the present invention to mice after oral administration, and evaluate the safety of the Chinese veterinary drug composition prepared in Example 2 of the present invention.

[0071] 2. Method

[0072] The maximum dose test method was used. 40 mice, weighing 25-30 g, half male and half male, were randomly divided into a control group and a drug group according to the preparation method of Example 2 of the present invention according to body weight, with 20 mice in each group. Example 2 of the present invention drug group with maximum concentration (4.30g crude drug / 1mL concentrated solution), maximum capacity (0.4mL / 10g body weight), gavage 2 times in 24h, 2 intervals 6 hours, observe animal behavior activities, mental state , skin color, stool and secretions, and body weight changes for 14 consecutive...

Embodiment 8

[0077] Embodiment 8: mouse acute toxicity test

[0078] 1. Purpose

[0079] Observe the acute toxic reaction of the Chinese veterinary drug composition prepared in Example 3 of the present invention to mice after oral administration, and evaluate the safety of the Chinese veterinary drug composition prepared in Example 3 of the present invention.

[0080] 2. Method

[0081] The maximum dose test method was used. 40 mice, with a body weight of 25-30 g, male and female, were randomly divided into a control group and a drug group according to the preparation method of Example 3 of the present invention, 20 in each group. Example 3 of the present invention drug group with maximum concentration (4.45g crude drug / 1mL concentrated solution), maximum capacity (0.4mL / 10g body weight), gavage 2 times in 24h, 2 intervals 6 hours, observe animal behavior activities, mental state , skin color, stool and secretions, and body weight changes for 14 consecutive days.

[0082] 3. Results

...

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Abstract

The invention relates to a traditional Chinese veterinary medicine composition for treating swine enzootic pneumonia. The composition is prepared from the following raw material medicine in parts by weight: 5 to 30 parts of mulberry leaves, 5 to 20 parts of chrysanthemum flowers, 1 to 10 parts of radix stemonae, 10 to 30 parts of herba houttuyniae and 3 to 15 parts of liquorice roots. The invention also provides a preparation method and application of the traditional Chinese veterinary medicine composition. The traditional Chinese veterinary medicine composition overcomes the defects of traditional Chinese medicine and western medicine in the prior art; the effects of eliminating phlegm by cooling, relieving cough and asthma, and strengthening the body resistance to eliminate pathogenic factors are achieved on pigs with the swine enzootic pneumonia; the cure rate is high; no toxic and side effects exist; the clinic curative effect is obvious; no medicine is remained; no drug resistanceis generated; the recurrence cannot easily occur; the body immunity of sick pigs can be improved. Compared with common powder, the liquid preparation has the advantages that the medication through awater drinking pipeline in a pig farm is convenient; the medicine utilization rate is improved; the medication quantity is reduced; the culture benefits of pig farms are improved.

Description

technical field [0001] The invention belongs to the field of traditional Chinese veterinary medicine, and relates to a Chinese veterinary medicine composition, in particular to a Chinese veterinary medicine composition for preventing and treating swine asthma, a preparation method and application thereof. Background technique [0002] Swine asthma (Mycoplasmal Pneumonia of Swine) is also known as endemic pneumonia (Swineenzootic pneumonia), swine mycoplasma pneumonia (Myeoplasmalpneumoriaofswine), swine mycoplasma pneumonia. It was first reported by Mare and Switzer that mycoplasma was isolated from lung tissue with pneumonia. The disease is a chronic respiratory infectious disease of pigs. The main symptoms are cough and wheezing, and the characteristic of the lesion is confluent bronchopneumonia, which often occurs in the anterior ventral side of the lung. The disease widely exists in all parts of the world, and the incidence rate is generally 50% to 80%. In some provin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/904A61P11/06A61P31/04
CPCA61K9/0095A61K36/287A61K36/484A61K36/605A61K36/78A61K36/904A61K2236/331A61K2236/39A61K2300/00
Inventor 汪猜皮灿辉
Owner 广州和仕康生物技术有限公司
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