62 results about "Swine Enzootic Pneumonia" patented technology

The present invention provides a mycoplasma vaccine, its preparation and application thereof. The foregoing mycoplasma vaccine comprises inactivated Mycoplasma hyorhinis ATIT-7 only or the mixture of inactivated Mycoplasma hyorhinis ATIT-7 and inactivated Mycoplasma hyopneumoniae, which effectively prevents the infection of swine enzootic pneumonia in pigs.

The invention discloses a traditional Chinese medicine for treating respiratory diseases and promoting growth for swine and a preparation method thereof. The traditional Chinese medicine is composed of plantain herb, herba patriniae, hindu datura flower, perilla leaf, trichosanthes kirilowii maxim and gelsmium elegans. The traditional Chinese medicine of the invention can effectively prevent and treat livestock respiratory diseases, such as swine enzootic pneumonia, infectious pleuropneumonia of swine, porcine reproductive and respiratory syndrome (PRRS), swine plague, swine influenza and thelike; meanwhile, the traditional Chinese medicine of the invention can improve animal productivity and promote animal growth. The traditional Chinese medicine of the invention has wide raw material resources, is safe and environmentally-friendly and has the advantages of simple preparation technology, low production cost and the like.

The invention discloses valnemulin hydrochloride emulsion for animals. Each 100ml of emulsion mainly comprises the following components by weight: 5 to 10g of valnemulin hydrochloride, 1 to 5g of emulsifier, 20 to 40g of oil for injection, 5 to 15g of ethanol and the balance of water for injection. The valnemulin hydrochloride emulsion for animals has the advantages of quick in vivo distribution and good target, can reduce the medicament residue in vivo and the toxic or side effect on the animals, and also can mask the unpleasant odor of the medicament, and improve the stability of the medicament. The valnemulin hydrochloride emulsion for animals can effectively treat gram-positive bacteria and mycoplasma infection, particularly swine dysentery and porcine enzootic pneumonia, and can reduce the using amount of the medicament and avoid medicament tolerance.

The invention provides a PCR primer for real-time fluorescent quantitative detection of Mycoplasma hyopneumoniae and a quantitative detection method thereof. The Mycoplasma hyopneumoniae is the main pathogen of swine enzootic pneumonia, is difficult to culture, and is difficult to detect quantitatively by microscope as the shape thereof is too small, and the traditional hyopneumoniae CCU detection and CFU detection have long time consumption, high pollution rate, different detection results due to different culture media, operation methods or criteria as well as difficult practical application. The real-time fluorescent quantitative PCR detection method established by the invention adopts the concentration-known standard plasmids containing target genes as reference, has the advantages of fast speed, high sensitivity and precise, and can be used for the quantitative or micro-detection of cultures of Mycoplasma hyopneumoniae and semi-finished products of vaccines.

The invention discloses a Chinese medicinal composition for preventing and treating swine enzootic pneumonia, which comprises the following components in part by weight: 25 to 40 parts of tatarian aster root, 15 to 28 parts of sessile stemona root, 10 to 20 parts of bitter apricot seed, 8 to 15 parts of white mulberry root-bark, 10 to 20 parts of loquat leaf and 8 to 20 parts of houttuynia cordata. The Chinese medicinal composition disclosed by the invention has high cure rate on swine enzootic pneumonia; by observing a curative effect of an artificially pathogenetic swine enzootic pneumonia model, high and middle dose groups of tested medicaments have obvious effects on the curative effect on swine enzootic pneumonia and weight increase of swines; and the Chinese medicinal composition is totally suitable for preventing and treating swine enzootic pneumonia.

The invention discloses a medicament of pure traditional Chinese medicine for treating swine enzootic pneumonia. And the medicament disclosed in the invention is an injection, which is prepared by performing processes including extraction and condensation on raw materials of Chinese medicinal materials based on different weight parts. The medicament disclosed in the invention is pure traditional Chinese medicine preparation based on certain weight ratios, and the preparation comprises the following components by weight: 4 to 16 parts of anemarrhena, 5 to 15 parts of bitter apricot kernel, 4 to 12 parts of ephedra stem, and 4 to 12 parts of balloonflower root. According to the invention, a traditional Chinese medicine prescription is finally determined after a plurality of experiments, and the medicament of the pure traditional Chinese medicine for treating the swine enzootic pneumonia has a good effect of synergistic interaction of medicaments, and has a powerful killing effect on a bacteria or a virus causing the swine enzootic pneumonia. Meanwhile, the body resistance of a swine can be strengthened quickly so as to prevent secondary infections and other diseases. The medicament of the pure traditional Chinese medicine for treating the swine enzootic pneumonia is safe, has little toxic-side effect and no-drug resistance, as well as can substitute for chemical machine of the kind. Moreover, the medicament of the pure traditional Chinese medicine for treating the swine enzootic pneumonia has effects of promoting recovery, clearing lung and discharging heat, and relieving cough and asthma. And the curative effect of the medicament of the pure traditional Chinese medicine for treating the swine enzootic pneumonia can be ensured.

The invention discloses a traditional Chinese medicine for treating respiratory disease of livestock and a preparation method thereof. The traditional Chinese medicine comprises five traditional Chinese medicinal materials of herba violae, turkey corn, aster, herba ephedra and radix scutellariae. The traditional Chinese medicine can be effectively used for treating diseases of swine enzootic pneumonia, swine contagious pleuropneumonia, porcine reproductive and respiratory syndrome, swine plague, swine influenza, infectious bronchitis of chicken, infectious laryngotracheitis of chicken and thelike, and has the advantages of environment protection without toxic and side effects, simple preparation process, low production cost and the like.

The invention relates to a compound propolis composition for treating swine enzootic pneumonia. The compound propolis composition for treating swine enzootic pneumonia is prepared by mixing 15 to 35 parts by weight of propolis, 15 to 35 parts by weight of rhizoma anemarrhenae, 15 to 35 parts by weight of almonds, 15 to 35 parts by weight of sessile stemona root, 15 to 45 parts by weight of platycodon grandiflorum, 15 to 35 parts by weight of bitter orange, 15 to 40 parts by weight of liquorice, 15 to 45 parts by weight of heartleaf houttuynia herb, 15 to 45 parts by weight of pericarpium citri reticulatae and 15 to 45 parts by weight of mung beans. The compound propolis composition has a reasonable formula, can be prepared by simple processes, has no toxic or side effects, does not produce pollution and drug residues, does not cause drug resistance, is crushed into superfine powder, and has high bioavailability and obvious treatment effects. In clinical, the compound propolis composition has special effects of treatment on swine enzootic pneumonia.

The invention discloses a traditional Chinese medicine composition for preventing and treating swine enzootic pneumonia. The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by weight: 6 parts of radix ophiopogonis, 6 parts of thunberg fritillary bulb, 6 parts of astragalus membranaceus, 6 parts of aristolochia debilis, 4 parts of scutellaria, 4 parts of cortex mori radicis, 4 parts of schisandra chinensis, 3 parts of honeysuckle, 3 parts of rhizoma anemarrhenae, 3 parts of bighead atractylodes rhizome, 3 parts of semen lepidii and 2 parts of radix glycyrrhizae. The invention further provides a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition for preventing and treating swine enzootic pneumonia has the benefits and advantages that the swine enzootic pneumonia can be effectively prevented and treated, and the preventing and treating effects are good; (2) the medicine can be fed by adopting water drinking or feed mixing, the operation is simple and the cost is low; (3) as the traditional Chinese medicine composition is Chinese herbal medicine preparation, the problems of drug tolerance and the like are avoided, and the probability of preventing and treating failure is greatly reduced; (4) the traditional Chinese medicine composition is pure traditional Chinese medicine compound, and has the advantages of multiple target, low residue in swine and good biosecurity when being acted on mycoplasma.

The invention discloses a veterinary compound florfenicol injection, and belongs to the field of veterinary preparations. Every 1 L of the injection comprises 50 g to 300 g of florfenicol, 5 g to 30 g of flunixin meglumine, 300 ml to 600 ml of isopropyl myristate, 150 ml to 450 ml of polyethylene glycol stearate, 0.5 g to 3 g of anhydrous sodium sulfite and 50 ml to 200 ml of water for injection. A preparation method is disclosed. The veterinary compound florfenicol injection has an obvious effect on poultry and livestock bacteriosis, morbus virosus and parasitic disease concurrency prevention and treatment and secondary bacterium infection, and especially effectively treats pig infective pleuropneumonia necrotic enteritis, piglet's yellow-white dysentery, swine enzootic pneumonia, atrophic rhinitis, metritis-mastistis-agalactia, clostridial enteritis of piglets, postpartum infection, haemophilus parasuis and the like. The preparation process is simple, good stability is achieved, cost is low, the water for injection is used for replacing part of an organic solvent, local analgesic does not need to be added, good liquidity and better needle passing performance are achieved, and irritation is reduced during injection.

The invention discloses a long-acting oxytetracycline injection and a preparation method of the long-acting oxytetracycline injection, and belongs to the technical field of veterinary preparations. Every 1000ml of the injection comprises the following components: 100-240 g of oxytetracycline, 120-140 g of sodium formaldehyde sulfoxylate, 300-400 g of propylene glycol, 80-120 g of magnesium chloride, 10-50 ml of ethanol amine, 50-100 g of pullulan-polyglutamic acid cross-linked polymer, 10-20 ml of honeysuckle extracting solution, 10-20 ml of buckwheat tea extracting solution, and the balance of water for injection. The product quality is stable, the long-acting oxytetracycline injection does not change the color and does not precipitate in the guarantee period, the drug effect lasts for 4 days by injecting once, and the long-acting oxytetracycline injection has better treatment effects on treating doldrums and hyperthermia caused by eperythrozoonosis, swine enzootic pneumonia, mycoplasma and rickettsial diseases of pigs, as well as high fever and systemic diseases.

The invention discloses a Chinese herbal medicine for swine enzootic pneumonia and a production method thereof, and belongs to the field of livestock farming treatment. The formula of the Chinese herbal medicine comprises the following components in parts by weight: 20-30 parts of flos lonicerae, 10-15 parts of Chinese ephedra, 5-10 parts of pinellia ternate, 12-18 parts of root bark of white mulberry, 15-20 parts of perillaseed, 16-23 parts of scutellaria baicalensis, 10-15 parts of almond and 5-10 parts of liquorice. The method comprises the following steps: respectively cleaning and drying the flos lonicerae, the Chinese ephedra, the pinellia ternate, the root bark of white mulberry, the perillaseed, the scutellaria baicalensis, the almond and the liquorice; crushing into powder, feeding 50-60g of powder to a big swine each time and 10-15g of powder to a small swine each time; mixing and feeding, and continuously feeding for 5 days. The Chinese herbal medicine is simple to operate, swine enzootic pneumonia can be thoroughly treated, growth of the swine is promoted, the growth period of the swine is shortened, and the meat quality is improved.

The invention discloses 30% lincomycin hydrochloride injection. The ratio of the 30% lincomycin hydrochloride injection by C18H34N2O6S is 10ml:3g. A preparation method of the 30% lincomycin hydrochloride injection includes the steps: adding water for injection accounting for 50% of prescription dosage; adding benzyl alcohol with the prescription dosage; stirring and dissolving the benzyl alcohol; adding lincomycin hydrochloride with the prescription dosage; dissolving the lincomycin hydrochloride; replenishing the water for injection to reach total quantity; performing fine filtration with a 0.22 micrometer filter element; sterilizing solution by circulating steam at the temperature of 100 DEG C to obtain the 30% lincomycin hydrochloride injection. The 30% lincomycin hydrochloride injection is a bacteriostatic agent and has a bactericidal effect on highly sensitive bacteria when at high concentration. By increasing the concentration, the bactericidal effect of lincomycin on the sensitive bacteria is remarkably enhanced. Asepsis of a medicine is ensured by a final bactericidal production process without affecting stability of the medicine, and efficacy is ensured. Clinically, the 30% lincomycin hydrochloride injection is commonly used for gram positive bacterial infection, particularly, infection of penicillin-resistant bacteria sensitive to the lincomycin such as staphylocosis, streptococcicosis and mastitis, and can also be used for swine treponematosis and swine enzootic pneumonia caused by mycoplasma infection.

The invention provides a Mycoplasma hyorhinis strain LYH, and a vaccine composition prepared from the Mycoplasma hyorhinis strain LYH, in particular to a vaccine composition comprising the Mycoplasma hyorhinis and Mycoplasma hyopneumoniae. The vaccine composition can be effective in prevention and treatment of swine enzootic pneumonia caused by Mycoplasma hyorhinis, Mycoplasma hyopneumoniae single infection or mixed infection. Especially in the circumstance of mixed infection, immune effect of the vaccine composition significantly exceeds that of each single vaccine.

The invention discloses a drinking water agent for preventing and treating livestock and poultry respiratory tract diseases and a preparation method thereof. The drinking water agent comprises chlortetracycline hydrochloride, tylosin tartrate and accessory materials. The preparation method of the drinking water agent comprises the following steps of respectively crushing chlortetracycline hydrochloride, tylosin tartrate and the accessory materials, carrying out sieving, respectively diluting the weighed hydrochloride, the weight tylosin tartrate and the weighed accessory materials having the weight equal to the total weight of the hydrochloride and tylosin tartrate in an equivalently progressive increasing dilution way, carrying out mixing, carrying out sieving to obtain a mixture, mixing the mixture and the residual accessory materials to obtain a uniform mixture, and carrying out sieving. The drinking water agent is suitable for swine enzootic pneumonia, actinobacillus pleuropneumonia, hemolytic streptococcus disease, swine dysentery, acute and chronic respiratory diseases and staphylococcosis in chickens. Through combined use, the drinking water agent can reduce a use concentration and shorten treatment time, has a certain effect of promoting growth of livestock and poultry in the growth stage, can effectively improve a forage utilization rate and has high safety.

The invention relates to a traditional Chinese medicine composite for treating swine enzootic pneumonia which is characterized in that the traditional Chinese medicine composite comprises the following medicines according to the weight parts (parts): 18-22 of senso, 22-26 of astragalus mongholicus, 8-12 of ginkgo, 10-14 of bitter almond kernel, 10-14 of aster, 5-9 of nodakenin, 5-9 of the fruit ofChinese magnoliavine, 1-4 of monkshood, 1-4 of black pepper, and 1-4 of rhizoma zingiberis. A preparation method is as follows: (1) weighing the medicines as raw materials according to the weight parts; (2) decocting for 2 times, adding 10 times amount of water in the first time, soaking for 30 minutes, and decocting for 2.0 hour; adding 10 times amount of water in the second time, decocting for1.0 hour, combining decoction solution, filtering and concentrating filter liquor till containing 1g primary drug per 1ml filter liquor; (3) adding alcohol and causing the alcohol containing amount tobe 60%, resting, filtering, recycling alcohol, filtering, adding purifier water to filter liquor till containing 1g primary drug per 5ml filter liquor, thus obtaining the traditional Chinese medicinecomposite. The traditional Chinese medicine composite has the beneficial effects that all components in the composites together play a role in tonifying Qi, astringing lung, relieving cough and asthma and warming phlegm and retained fluid. The composite can be quickly absorbed, has obvious effect, high safety coefficient, and has no medicine residual and non toxic-side effect.

The invention discloses a live vaccine for treating swine enzootic pneumonia. The live vaccine is characterized in that the inactivated vaccine contains inactivated porcine mycoplasmas strains and adjuvants allowed by veterinary biological products, the inactivated strains are used as a water phase and the adjuvants are used as an oil phase, and the water phase and the oil phase are emulsified according to a volume ratio of 1: 1-1: 3. The prepared vaccine is high in antigen stability, high in immunogenicity, high in antigen recovery rate, high in vaccine safety, capable of reducing the probability of adverse reactions and improving the immune effect, simple in preparation method and low in cost. Therefore, the live vaccine for treating the swine enzootic pneumonia provided by the inventionhas a wide market prospect.

The invention discloses a traditional Chinese medicine composition for treating swine enzootic pneumonia, a method for preparing the same and application thereof. The traditional Chinese medicine composition is prepared from the following materials by weight portion: 10 to 30 portions of common alstonia bark or leaf, 5 to 15 portions of origanum vulgare and 8 to 24 portions of mullein flower; the origanum vulgare is soaked and distilled to collect distillate; waste residue and waste liquid after distillation are added with the common alstonia bark or leaf and the mullein flower for cooking for three times; the decoction solutions are mixed and concentrated to be thick, added with ethanol to adjust the alcohol concentration to between 60 and 70 percent, and subjected to deposition, filtration and concentration; the concentrated medicine liquid is added with ethanol to adjust the alcohol concentration to between 75 and 80 percent, and subjected to deposition, filtration and concentration; the medicine liquid is added with distilled water, and subjected to cold storage deposition, filtration and concentration; the distillate of the origanum vulgare and the concentrated solution of the common alstonia bark or leaf and the mullein flower are mixed to obtain the traditional Chinese medicine composition. The curing rate of the traditional Chinese medicine composition on the swine enzootic pneumonia is nearly 95 percent; and when the traditional Chinese medicine composition is used to prepare a veterinary drug for treating the swine enzootic pneumonia, the veterinary drug has the advantages of small side effect, safe and convenient use and quick absorption.

The invention discloses a traditional Chinese medicine composition for pigs and a preparation method and application of the traditional Chinese medicine composition for pigs. The composition is prepared from, by weight 6-18 parts of Fructus Broussonetiae, 15-45 parts of Schizomussaenda Dehiscens, 9-27 parts of Radix Mahoniae and 8-24 parts of Rhapis Excelsa. The preparation method includes: mixing the four traditional Chinese medicines, adding water, soaking, decocting for 2-3 times, combining decoctions, concentrating to a thick state, using ethyl alcohol to adjust the alcohol concentrate to 60%-70%, precipitating, filtering, adding ethyl alcohol to concentrated medicine liquid to adjust the alcohol concentration to 75%-80%, precipitating, filtering, concentrating filtrate, adding distilled water, refrigerating, precipitating, filtering, and concentrating to obtain a required dosage form. The traditional Chinese medicine composition is used for preparation of Chinese veterinary drugs for treating blue ear disease, porcine circovirus disease, pseudorabies, necrotic enteritis, swine enzootic pneumonia and haemophilus parasuis and is free of evident toxic and side effects and safe and convenient to use.

The invention discloses a bacterial liquid for treating swine enzootic pneumonia syndrome. The bacterial liquid is prepared from the following raw materials in parts by weight: 4 to 6 parts of fresh semen cuscutae, 4 to 6 parts of radix astragali, 3 to 5 parts of poria cocos, 3 to 5 parts of raw rhizoma pinelliae, 3 to 5 parts of shamrock herb, 5 to 7 parts of dried tangerine peel, 4 to 6 parts ofradix codonopsis, 2 to 4 parts of peucedani decursivi radix, 3 to 5 parts of fructus trichosanthis, 4 to 6 parts of folium mori, 3 to 5 parts of radix ophiopogonis, 4 to 6 parts of fructus schisandrae chinensis, 3 to 5 parts of radix sophorae subprostratae, 3 to 5 parts of radix platycodonis, and 3 to 5 parts of herba spirodelae. The invention also discloses a preparation method of the bacterialliquid and application of the bacterial liquid. The bacterial liquid for treating swine enzootic pneumonia syndrome prepared by the invention contains a plurality of Chinese herbal medicine ingredients, and has the effects of expelling phlegm and relieving cough, clearing away heat and detoxifying, and freeing lung and relieving asthma. The treatment for pigs with swine enzootic pneumonia syndromeis effective, the course of treatment is short, no drug resistance is generated, and the body immunity is regulated.