High-strength polylactic acid bone fixation material and preparation method thereof

A polylactic acid bone and fixation material technology, applied in medical science, surgery, etc., can solve the problems of poor viscoelasticity, limited stretching ratio, difficult mechanical strength, etc.
CN107778435AActive Publication Date: 2018-03-09SICHUAN UNIV
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
SICHUAN UNIV
Publication Date
2018-03-09

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Abstract

The invention discloses a high-strength polylactic acid bone fixation material and a preparation method thereof. The high-strength polylactic acid bone fixation material is characterized in that a multifunctional long-chain flexible branching agent is prepared by virtue of reaction of polyether and aliphatic isocyanate and is combined with a multifunctional epoxy compound for use, and long-chain branched polylactic acid is prepared by virtue of a simple, convenient and feasible reactivity processing method, so that the entanglement degree of chains among polylactic acid molecules is increased,and the tensile property of polylactic acid is improved; and by introducing a polyether long chain, polylactic acid is endowed with relatively good impact toughness, and a high-power uniformly-orientated polylactic acid material is prepared on that bases by virtue of a double-shaft solid phase thermal stretching method, so that the mechanical strength of the polylactic acid material as the bone fixation material is substantially enhanced, and meanwhile, the biocompatibility of the polylactic acid material is improved.
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Description

1. Technical field

[0001] The invention relates to a high-strength polylactic acid bone fixation material and a preparation method thereof, belonging to the technical field of biomedical polymer materials and polymer material processing. 2. Background technology

[0002] Polylactic acid is non-toxic, non-irritating, has excellent biocompatibility and complete biodegradability, and is a biodegradable biomaterial approved by the FDA for human use. The development of high-strength absorbable orthopedic fixation materials based on polylactic acid began in the 1970s, and is considered the most promising due to its superior biocompatibility, good biomechanical properties and appropriate degradation speed. The promising biomedical material has irreplaceable advantages in the field of bone repair, such as it can be degraded in the body and excreted with metabolites, thus avoiding secondary surgery. However, the mechanical strength of polylactic acid is not high, and it does not hav...

Claims

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