Method for detecting polyvinylpyrrolidone content in contact lenses caring composition
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A technology of polyvinylpyrrolidone and contact lenses, applied in the field of chemical analysis and detection, to achieve high accuracy, small result error and eliminate interference
Inactive Publication Date: 2018-04-06
HAICHANG CONTACT LENSES +2
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Adopt ultraviolet absorption spectrometry to quantitatively measure the content of polyvinylpyrrolidone in the contact lens care composition and there is no report so far
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[0090] PVP test result in table 6 contact lens care solution sample C
[0091]
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Abstract
The invention relates to a method for detecting polyvinylpyrrolidone content in a contact lenses caring composition. The method comprises the following steps: respectively preparing a stock solution,a blank stock solution, and a caring composition standard stock solution, using a linear relation of an absorption value y and concentration x of polyvinylpyrrolidone under different concentrations todetermine the polyvinylpyrrolidone concentration in the nursing composition, which is pretreatment of the to-be-measured caring composition, determining polyvinylpyrrolidone concentration in the to-be-measured caring composition, taking the blank stock solution as a blank solvent and a reference solution respectively to obtain an ultra-violet absorption curve y=ax+b of the to-be-measured caring composition corresponding to an ultra-violet absorption wavelength, taking a ultra-violet absorption value of the to-be-measured caring composition, and substituting the ultra-violet absorption value into the standard curve of the polyvinylpyrrolidone concentration in the caring composition to obtain the polyvinylpyrrolidone concentration in the to-be-measured contact lens caring composition. The method has the advantages of simpleness and rapidity, low detection limit, and sensitive and stable signal, and can satisfy detection requirement.
Description
technical field [0001] The invention belongs to the field of chemical analysis and detection, in particular to a method for detecting the content of polyvinylpyrrolidone in a contact lens care composition. Background technique [0002] Polyvinylpyrrolidone is a water-soluble amide polymer. Due to its excellent solubility, film-forming property, complexation property and certain surface activity, it is widely used in medicine, daily chemicals, food, textile, printing and dyeing, Widely used in many industrial fields such as coatings. Polyvinylpyrrolidone is odorless, tasteless, almost non-toxic, non-irritating to skin and eyes, and has no skin sensitization. [0003] As a non-ionic polymer compound, polyvinylpyrrolidone has been widely concerned and applied because of its excellent solubility, low toxicity and good biocompatibility. Polyvinylpyrrolidone is used in contact lens care products mainly to improve their lubricity. [0004] The qualitative identification of polyv...
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