Polysaccharide degradation method and low-molecular-weight polysaccharide

Abstract

The invention discloses a polysaccharide degradation method and low-molecular-weight polysaccharide, and relates to the field of degradation of a polysaccharides compound. The polysaccharide degradation method comprises the following step: treating a polysaccharide solution by adopting a high-pressure cell crushing device to obtain the low-molecular-weight polysaccharide. The polysaccharide degradation method disclosed by the invention overcomes the shortcomings that a conventional ultrasonic method is long in time and low in efficiency, a chemical method is low in reaction regularity and hasa hardly controlled process, and an enzyme hydrolysis method is low in applicability and high in cost and can hardly realize large-scale production. According to the method, the high-pressure cell crushing device is adopted to degrade polysaccharide, so that the polysaccharide which has a relatively low molecular weight is obtained by shearing and collision at high pressure; the molecular weight of the polysaccharide can be precisely controlled by adjusting the treatment pressure and the number of times; the polysaccharide degradation method has the advantages of small noise, zero pollution and high speed, and the physiological activity of the polysaccharide cannot be destroyed.

Description

technical field [0001] The invention relates to the field of degradation of polysaccharide compounds, in particular to a polysaccharide degradation method and low molecular weight polysaccharides. Background technique [0002] Polysaccharides are a class of natural products with various biological activities such as immune regulation, anti-tumor, anti-virus, anti-infection, and hypoglycemia. Polysaccharides can be extracted from plants, animals, and microorganisms, but these polysaccharides tend to have relatively large molecular weights, dissolve slowly during use, and are difficult to absorb, which affects the bioavailability of polysaccharides, and polysaccharides with lower molecular weights tend to have better bioavailability , are easier to absorb, so polysaccharides need to be degraded to obtain polysaccharides with smaller molecular weights. [0003] Studies have found that the biological activity of some polysaccharides is closely related to their molecular weight,...

AI Technical Summary

Problems solved by technology

[0004] At present, polysaccharide degradation methods include physical, chemical and biological methods, among which physical methods such as ultrasonic method, radiation method, etc., ultrasonic method takes a long time, low efficiency, energy consumption and noise; The requirements are high and it is easy to cause harm to the operator

Chemical methods such as acid hydrolysis, oxidative degradation, etc. The reaction regularity of acid hydrolysis and oxidative degradation methods is poor, the process is difficult to control, the reproducibility is not good, and the reaction environment is not neutral. After the reaction is completed and neutralized, a large amount of inorganic salts are introduced. Step desalination, resulting in a decrease in product yield and an increase in production costs

The biological method is mainly enzymatic hydrolysis. The enzymatic hydrolysis uses the corresponding glycosidase to degrade polysaccharides. Although the effect is good, the applicability is poor. Many types of polysaccharides have not yet found suitable enzymes to realize enzymatic hydrolysis, and the cost is expensive, so it is difficult to apply mass production

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