Small optical resolution photoacoustic microscope based on micro-electromechanical scanning galvanometer

Abstract

A small optical resolution photoacoustic microscope based on a micro-electromechanical scanning galvanometer belongs to the technical fields of automatic control and imaging. The small optical resolution photoacoustic microscope includes a light source assembly, a single-mode fiber coupling assembly, a light beam scanning assembly, a reflective support 4-1, a signal acquisition assembly and a computer, the computer controls pulsed laser emitted from the light source assembly to be collimated by the single-mode fiber coupling assembly and then enter the light beam scanning assembly, the light beam scanning assembly includes the micro-electromechanical scanning galvanometer 3-4 and a function generator 3-5, the computer controls the micro-electromechanical scanning galvanometer 3-4 to rotatethrough the function generator 3-5, the pulsed laser entering the light beam scanning assembly is reflected by the micro-electromechanical scanning galvanometer 3-4, and reacts with a target object through the reflective support 4-1 in order to generate a photoacoustic signal, and the photoacoustic signal is reflected by a light-transmitting and acoustic-reflecting sheet, is acquired by the signal acquisition assembly, is transmitted to the computer, and is stored and processed. The small optical resolution photoacoustic microscope has the advantages of small size, light weight, wide scanningrange and high scanning precision.

Description

technical field [0001] The invention relates to the technical field of automatic control and imaging, in particular to a small photoacoustic microscope with optical resolution based on a microelectromechanical (MEMS) scanning vibrating mirror. Background technique [0002] Optical resolution photoacoustic microscopy is a non-destructive medical imaging technology with high resolution and high contrast emerging in the past decade, which is widely used in various medical research. Different from traditional optical microscopes, optical-resolution photoacoustic microscopy needs to acquire images by point-by-point scanning, so a high-precision scanning mechanism is crucial for optical-resolution photoacoustic microscopy. At present, when applying optical resolution photoacoustic microscope to image the target object at home and abroad, the application of high-performance stepping motor or scanning galvanometer is the most common method to achieve high-precision scanning. Howeve...

AI Technical Summary

Problems solved by technology

However, these scanning mechanisms are usually bulky and heavy, and it is still difficult to meet the urgent needs of small and lightweight portable imaging systems in many medical applications.

[0003] In response to the above problems, many research groups at home and abroad have proposed many solutions, such as using a magnetically driven scanning mirror to simultaneously scan the focused laser beam and ultrasonic waves to achieve two-dimensional scanning, so as to build a set of miniaturized optical resolution lasers. Compared with the traditional photoacoustic microscope with optical resolution, the volume of the acoustic microscope has been reduced to a certain extent, and it can be hand-held, but it is still relatively bulky and has a large loss in image quality, so it still cannot be applied to endoscopic imaging and oral inspection. And applications such as brain imaging of freely moving small living animals

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