Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Gynecological gel containing chitosan oligosaccharide and preparation method thereof

A chitosan oligosaccharide and gynecological technology, applied in the field of medicine, can solve the problems of high irritation of the affected area and poor long-term use effect, and achieve the effect of low irritation and high safety

Active Publication Date: 2020-05-08
GUANGZHOU RAINHOME PHARM&TECH CO LTD
View PDF4 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to overcome the poor long-term use effect of gynecological antibacterial drugs in the prior art, the technical deficiency that the medicine is more irritating to the affected area, the invention provides a kind of gynecological gel containing chitosan oligosaccharide, in the gel Contains a variety of pharmaceutical components as its active ingredients, among which the components have a significant synergistic effect on anti-vaginitis pathogenic bacteria, which is less irritating to the vagina, and is suitable for popularization and application

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Gynecological gel containing chitosan oligosaccharide and preparation method thereof
  • Gynecological gel containing chitosan oligosaccharide and preparation method thereof
  • Gynecological gel containing chitosan oligosaccharide and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] Embodiment 1 The present invention contains gynecological gel of chitosan oligosaccharide and preparation method thereof

[0020] A gynecological gel containing chitosan oligosaccharide, which is prepared from the following components by weight: 1 part of chitosan oligosaccharide, 0.5 part of chamomile extract, 0.2 part of natural lactic acid, vitamin B 5 0.01 parts, glycerin 2 parts, soybean isoflavones 0.5 parts, carbomer 0.5 parts, water 90 parts.

[0021] The preparation method of the chamomile extract is as follows: dry the chamomile medicinal material through a 40-mesh sieve, add 3% sodium hydroxide solution with a volume three times the mass of the chamomile medicinal material, and control the temperature at 50°C to carry out the hydrolysis reaction. After hydrolysis for 4 hours, filter, wash and filter the chamomile medicinal material with drinking water until the pH value of the water washing liquid is 7, dry the chamomile medicinal material after washing, add...

Embodiment 2

[0023] Embodiment 2 The present invention contains gynecological gel of chitosan oligosaccharide and preparation method thereof

[0024] A gynecological gel containing chitosan oligosaccharide, which is prepared from the following components by weight: 2 parts of chitosan oligosaccharide, 0.8 parts of chamomile extract, 0.6 part of natural lactic acid, vitamin B 5 0.02 parts, glycerin 6 parts, soybean isoflavones 1.3 parts, carbomer 6.25 parts, water 95 parts.

[0025]Wherein the preparation method of the chamomile extract is as follows: dry the chamomile medicinal material through a 40-mesh sieve, add 3% sodium hydroxide solution of 4 times the volume of the chamomile medicinal material to it, and control the temperature to 60°C to carry out the hydrolysis reaction, Filtrate after hydrolysis for 5 hours, wash and filter the chamomile medicinal material with drinking water until the pH value of the water washing liquid is 7, dry the chamomile medicinal material after washing,...

Embodiment 3

[0027] Embodiment 3 The present invention contains gynecological gel of chitosan oligosaccharide and preparation method thereof

[0028] A gynecological gel containing oligochitosan, which is prepared from the following components by weight: 3 parts of oligochitosan, 1 part of chamomile extract, 1 part of natural lactic acid, vitamin B 5 0.03 parts, glycerin 10 parts, soybean isoflavones 2 parts, carbomer 12 parts, water 100 parts.

[0029] The preparation method of the chamomile extract is as follows: dry the chamomile medicinal material through a 40-mesh sieve, add 3% sodium hydroxide solution with a volume 5 times the mass of the chamomile medicinal material, and control the temperature at 70°C to carry out the hydrolysis reaction. After hydrolysis for 6 hours, filter, wash and filter the chamomile medicinal material with drinking water until the pH value of the water washing liquid is 8, dry the chamomile medicinal material after washing, add 30% acetone aqueous solution ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention relates to chitooligo saccharide-containing gynaecological gel and a preparation method thereof, and belongs to the field of medicines. In order to overcome the technical shortcomings that the long-time use effect of a gynaecological antibacterial drug is poor and the drug is relatively high in irritation to a diseased part. The chitooligo saccharide-containing gynaecological gel provided by the invention contains various drug components used as active components; all the components achieve an obvious synergistic effect in the aspect of resisting colpitis pathogenic bacteria. Thechitooligo saccharide-containing gynaecological gel is low in irritation to the vagina and is suitable for being popularized and applied.

Description

technical field [0001] The invention relates to a gynecological gel containing chitosan oligosaccharide and a preparation method thereof, belonging to the field of medicine. Background technique [0002] Vaginitis is inflammation of the vagina. Due to the characteristics of anatomical tissue, the vagina of normal healthy women has a natural defense function against the invasion of pathogens. For example, the closure of the vaginal opening, the close contact of the front and rear walls of the vagina, the hyperplasia of vaginal epithelial cells and keratinization of surface cells under the influence of estrogen, and the balance of vaginal pH balance inhibits the reproduction of pathogens that adapt to alkaline, while the cervical mucus appears Alkaline, when the natural defense function of the vagina is destroyed, pathogens are easy to invade, leading to vaginal inflammation. Under normal circumstances, there are aerobic bacteria and anaerobic bacteria living in the vagina, ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/06A61K36/28A61P15/02A61K31/722A61K31/19A61K31/702A61K31/352A61K31/197A61K31/015
CPCA61K9/0034A61K9/06A61K31/015A61K31/19A61K31/197A61K31/352A61K31/702A61K31/722A61K36/28A61K47/32A61K2236/333A61K2236/35A61K2236/39A61K2236/51A61K2300/00
Inventor 黄海艳车七石
Owner GUANGZHOU RAINHOME PHARM&TECH CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com