A programmable and modular pdms microfluidic chip mold system

Abstract

The invention discloses a programmable modularized PDMS (Polydimethylsiloxane) microfluidic chip mold system and belongs to the technical field of microfluidics. A plurality of silicon chip mold module mounting areas are arranged on a mold assembling platform; a plurality of bosses are arranged in the middle of the different mounting areas; processed micro structures are arranged on silicon chips;a plurality of silicon chip mold modules with different micro structure patterns are mounted on the mold assembling platform through the bosses. By adopting the system, molds for manufacturing PDMS microfluidic chips are designed and manufactured in a modularization manner, microfluidic chip mold modules with different functions are processed by using the silicon chips, the silicon chips are further arranged and combined by using the mold assembling platform to form a microfluidic chip system mold with complex functions, and finally microfluidic chips are manufactured from PDMS through mold reversing. By adopting the system, the flexibility of the microfluidic chip processing process can be remarkably improved, the chip processing cost can be remarkably reduced, the processing process issimple to operate, and the system is applicable to microfluidic chip manufacturing with single or complex functions on the basis of PDMS materials.

Description

technical field [0001] The invention relates to a programmable modular PDMS (polydimethylsiloxane) microfluidic chip mold system, which belongs to the field of microfluidic technology. Background technique [0002] Microfluidic technology refers to the technology of controlling fluid at the micron scale. It can realize multiple detection functions on one chip, and its detection speed, accuracy and production cost are much lower than traditional methods. It is widely used in analytical chemistry, life science and medical treatment areas of diagnosis. The microfluidic chip integrates the basic operation units such as sample preparation, reaction, separation, and detection in the analysis process of biology, chemistry, and medicine into a micron-scale chip, and automatically completes the entire analysis process. The preparation materials of microfluidic chips can be divided into polymer materials, glass, paper and so on according to the application. [0003] PDMS is one of t...

AI Technical Summary

Problems solved by technology

Mold processing is a key step in the preparation of PDMS microfluidic chips. The processing process is complex, the equipment cost is high, the time is long, and the micro-processing experience and technical requirements of the experimenters are high.

In actual use, for microfluidic chips with different functions, it is necessary to repeat photolithography, inversion, packaging and other processes, which not only reduces the processing efficiency, but also increases the processing cost and time

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