Composite polysaccharide with functions of clearing damp, tonifying spleen, reducing fat and losing weight as well as preparation method and application thereof

A compound polysaccharide, a technology for removing dampness and strengthening the spleen, applied to the compound polysaccharide with functions of removing dampness and strengthening the spleen, reducing lipid and weight loss, and the preparation thereof, and the field of compound polysaccharide and preparation thereof, can solve the problems of insignificant effect of reducing lipid and weight loss, etc. Improve mental outlook, reduce accumulation, reduce fasting blood sugar

Inactive Publication Date: 2018-07-06
INFINITUS (CHINA) CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are a variety of weight loss compound preparations on the market, such as slimming Jiangzhiling capsule (containing ginseng, knotweed, senna, sodium alginate, etc.), detoxification tea (raw rhubarb, raw hawthorn, Alisma, licorice, etc.), There are also ancient prescriptions from famous doctors, such as Erchen Decoction, Xiaochengqi Decoction, etc., but the effect of reducing fat and losing weight is not significant

Method used

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  • Composite polysaccharide with functions of clearing damp, tonifying spleen, reducing fat and losing weight as well as preparation method and application thereof
  • Composite polysaccharide with functions of clearing damp, tonifying spleen, reducing fat and losing weight as well as preparation method and application thereof
  • Composite polysaccharide with functions of clearing damp, tonifying spleen, reducing fat and losing weight as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0037] Embodiment 1: the preparation of Magnolia officinalis polysaccharide

[0038] Weigh an appropriate amount of magnolia bark, add 20 times of water, decoct for 2 hours, filter, collect the filtrate, add 20 times of water to the filter residue, decoct for 1 hour again, filter, and combine the filtrate twice; concentrate the filtrate to contain 100g of magnolia bark crude drug per 100mL, Add 95% ethanol to 80% ethanol volume, let it stand overnight, centrifuge to obtain supernatant and precipitate, freeze-dry the precipitate or dry it at 70°C, and pulverize to obtain magnolia polysaccharide.

Embodiment 2

[0039] Embodiment 2: Preparation of Atractylodes macrocephala polysaccharide

[0040] Weigh an appropriate amount of Atractylodes macrocephala, add 20 times of water, decoct for 2 hours, filter, collect the filtrate, add 20 times of water to the filter residue, decoct for 1 hour again, filter, and combine the filtrates twice; concentrate the filtrate to contain 100g of Atractylodes macrophylla per 100mL, add 95 % ethanol to 80% ethanol volume, stand overnight, centrifuge to obtain the supernatant and precipitate, freeze-dry or dry the precipitate at 70°C, and pulverize to obtain Atractylodes polysaccharide.

Embodiment 3

[0041] Embodiment 3: the preparation of tangerine peel polysaccharide

[0042] Weigh an appropriate amount of tangerine peel, add 20 times of water, decoct for 2 hours, filter, collect the filtrate, add 20 times of water to the filter residue, decoct for 1 hour again, filter, and combine the filtrate twice; concentrate the filtrate to contain 100g of tangerine peel crude drug per 100mL, add 95 % ethanol to 80% ethanol volume, stand overnight, centrifuge to obtain the supernatant and precipitate, freeze-dry the precipitate or dry it at 70°C, and pulverize to obtain the orange peel polysaccharide.

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PUM

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Abstract

The invention belongs to the field of medicines and health-care products, and particularly discloses composite polysaccharide, a preparation method thereof and application thereof to products for clearing damp, tonifying spleen, reducing fat and losing weight. The composite polysaccharide is prepared from mangnolia officinalis, rhizoma atractylodis macrocephalae, dried orange peel, cortex lycii radicis and black mulberry. The preparation method of the composite polysaccharide comprises water extraction and alcohol precipitation. The composite polysaccharide provided by the invention can obviously reduce body mass increasing rate of a nutritional obesity rat model and retard increment of body weight and Lee's index, can reduce fat mass, fat body ratio and fat cell number, reduce accumulation of internal fat, reduce triglyceride and total cholesterol, adjust high-density lipoprotein and high-density lipoprotein, improve hyperlipidemia, reduce fasting blood glucose, improve oral glucose tolerance and improve the appearance condition and the mental outlook of the nutritional obesity rat, has the effect which is obviously excellent than that of each single polysaccharide component, andcan be used for preparing the medicines or health-care food with effects of clearing damp, tonifying spleen, reducing fat and losing weight.

Description

technical field [0001] The invention belongs to the field of medicines and health care products, and specifically relates to a compound polysaccharide and its preparation method and application, in particular to a compound polysaccharide with the functions of dispelling dampness and invigorating the spleen, reducing fat and losing weight, and its preparation method and application. Background technique [0002] Obesity is a chronic endocrine and metabolic disease caused by a series of eating regulation and energy metabolism disorders caused by specific biochemical factors, energy intake exceeds consumption and is stored in the body in the form of fat, and abnormal body weight. Obesity is often determined by body mass index (BMI) (BMI = body mass (kg) / height (m 2 )). BMI ≥ 25 is considered overweight, and BMI ≥ 30 is considered obese. The World Health Organization announced that obesity is a disease in 1999. There are about 250 million obese patients with a BMI over 30 in t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/815A61K36/752A61K36/605A61K36/575A61K36/284A61K31/715A61P1/00A61P3/06A61P3/04A23L33/105
CPCA23L33/105A23V2002/00A61K31/715A61K36/284A61K36/575A61K36/605A61K36/752A61K36/815A61K2300/00A23V2200/32A23V2200/3262A23V2200/328A23V2200/332A23V2250/21
Inventor 胡明华徐路从仁怀马方励肖凌云
Owner INFINITUS (CHINA) CO LTD
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