Vitamin D3 soft capsule and preparation method thereof

A technology of vitamins and soft capsules, which is applied in capsule delivery, pharmaceutical formulations, medical preparations containing active ingredients, etc. It can solve the problems of single vitamin D products, inconvenient carrying and taking, and the need for refrigerator storage, etc., and achieve huge social and economic benefits. Benefits, good antioxidant properties, easy application

Inactive Publication Date: 2018-08-17
桑艳红
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

A common way to supplement vitamin D3 is to take vitamin D oral preparations. At present, there are relatively few domestic pharmaceutical companies that produce oral vitamin D preparations. The vitamin D products produced are single, mostly vitamin AD drop pills, water preparations, and injections, which usually need to be stored In the cold environment of nitrogen, no light and no acid, there are defects such as inconvenient to carry and take, and need to be stored in a refrigerator. At the same time, because it is easy to oxidize, it is often necessary to add artificially synthesized antioxidants, which will cause certain adverse effects on the human body.

Method used

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  • Vitamin D3 soft capsule and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A vitamin D3 soft capsule, consisting of contents and a capsule skin, the contents include the following raw materials in parts by weight: 25 parts of vitamin D3, 1 part of asparagus extract, 1 part of cornstarch, 0.4 part of white beeswax, 4 parts safflower oil, 25 parts olive oil, 0.5 part soybean lecithin. Wherein, the preparation method of the asparagus extract is to wash the asparagus, then put it into a steam pressure cooker, add an appropriate amount of deionized water for high-temperature and high-pressure extraction, the pressure of the high-temperature and high-pressure extraction is 0.7MPa, and the time is 35min. Concentrate under reduced pressure to obtain the asparagus extract; the capsule skin includes the following raw materials in parts by weight: 11 parts of gelatin, 3 parts of glycerin, 0.01 part of sweetener, and 1 part of walnut oil; the sweetener is wood sugar alcohol.

[0028] In the present embodiment, the preparation method of the vitamin D3 sof...

Embodiment 2

[0035] A vitamin D3 soft capsule, consisting of contents and a capsule skin, the contents include the following raw materials in parts by weight: 45 parts of vitamin D3, 8 parts of asparagus extract, 8 parts of cornstarch, 3 parts of white beeswax, 15 parts safflower oil, 45 parts olive oil, 4 parts soybean lecithin. Wherein, the preparation method of the asparagus extract is to wash the asparagus, then put it into a steam pressure cooker, add an appropriate amount of deionized water to carry out high-temperature and high-pressure extraction, the pressure of the high-temperature and high-pressure extraction is 0.7MPa, and the time is 35min. Concentrate under reduced pressure to obtain the asparagus extract; the capsule skin includes the following raw materials in parts by weight: 11 parts of gelatin, 3 parts of glycerin, 0.01 part of sweetener, 1 part of walnut oil; the sweetener is wood sugar alcohol.

[0036] In the present embodiment, the preparation method of the vitamin ...

Embodiment 3

[0043] A vitamin D3 soft capsule, consisting of contents and a capsule skin, the contents include the following raw materials in parts by weight: 35 parts of vitamin D3, 4.5 parts of asparagus extract, 4.5 parts of cornstarch, 1.7 parts of white beeswax, 9.5 parts safflower oil, 35 parts olive oil, 2.3 parts soybean lecithin. Wherein, the preparation method of the asparagus extract is to wash the asparagus, then put it into a steam pressure cooker, add an appropriate amount of deionized water to carry out high-temperature and high-pressure extraction, the pressure of the high-temperature and high-pressure extraction is 0.7MPa, and the time is 35min. Concentrate under reduced pressure to obtain the asparagus extract; the capsule skin includes the following raw materials in parts by weight: 11 parts of gelatin, 3 parts of glycerin, 0.01 part of sweetener, 1 part of walnut oil; the sweetener is wood sugar alcohol.

[0044] In the present embodiment, the preparation method of the...

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Abstract

The invention discloses a vitamin D3 soft capsule which is composed of an inclusion and a capsule skin. The inclusion comprises the following raw materials: vitamin D3, an asparagus extract, corn starch, white beeswax, safflower seed oil, olive oil and soybean phospholipid. The invention also discloses a preparation method of the vitamin D3 soft capsule. The prepared vitamin D3 soft capsule has good stability; through synergistic effect of the asparagus extract and the safflower seed oil, the vitamin D3 soft capsule has good antioxidant property without addition of an artificial synthetic antioxidant, is safe, has no toxicity and has no need for low-temperature storage. Moreover, since the product is made into the soft capsule, the soft capsule is convenient to carry and take, is more convenient to apply in medical and health care, and has social and economic benefits with great prospects.

Description

technical field [0001] The invention relates to the medical and health field, in particular to a vitamin D3 soft capsule and a preparation method thereof. Background technique [0002] Vitamin D is a fat-soluble vitamin and is also regarded as a hormone precursor that acts on calcium and phosphorus metabolism. There are at least 10 known types of vitamin D, but the most important are vitamin D2 (ergocalciferol) and vitamin D3 (cholecalciferol). Among them, vitamin D3 is transformed from 7-dehydrocholesterol contained in the epidermis and dermis of most advanced animals by ultraviolet (wavelength 265-228nm) irradiation. Vitamin D3 is an active form with the highest biological metabolism rate in vitamin D. . Studies have shown that vitamin D3 can improve the body's absorption of calcium and phosphorus, and make the levels of plasma calcium and phosphorus reach saturation; promote growth and bone calcification, and promote tooth health; increase phosphorus absorption through ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/593A61K36/899A61K36/286A61K9/48A61K47/44A61K47/42A61K47/36A61P3/02A61P3/04A61P19/10
CPCA61K9/4825A61K9/4858A61K9/4866A61K31/593A61K36/286A61K36/899A61P3/02A61P3/04A61P19/10A61K2300/00
Inventor 桑艳红
Owner 桑艳红
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