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Preparation method of compound medical dressing

A medical and polymer technology, which is applied in the field of preparation of composite medical dressings, can solve the problems of expensive equipment, low electrospinning efficiency, and inability to meet industrialization requirements, and achieve simple procedures, increase antibacterial function, and maintain the effect of action

Inactive Publication Date: 2018-10-16
JIANGSU YIMAO FILTER MEDIA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the efficiency of electrospinning is extremely low, and the equipment is expensive, which cannot meet the requirements of industrialization

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0028] A kind of preparation method of composite medical dressing, described preparation method is carried out according to the following steps:

[0029] a. Preparation of hygroscopic layer

[0030] According to the following mass percentage:

[0031] Calcium Alginate Fiber 50-70%

[0032] Viscose 10-30%

[0033] Chitosan Fiber 10-30%

[0034] Mix calcium alginate fiber, viscose fiber and chitosan fiber, open, card, lay the net, and then go through acupuncture to obtain a grammage of 20-60g / m 2 moisture-absorbing layer. Calcium alginate fiber has good moisture absorption and moisturizing properties, but calcium alginate fiber alone is not easy to card into a web. After adding viscose fiber, it not only reduces the production cost, but also makes calcium alginate fiber easy to card. Combined with chitosan fiber The antibacterial property makes the moisture-absorbing layer have a certain antibacterial function and resists the invasion of external bacteria.

[0035] b. Prep...

Embodiment 1

[0044] According to the above method, the preparation method of composite medical dressing comprises the following steps:

[0045] a. Preparation of hygroscopic layer

[0046] Mix calcium alginate fiber with a mass fraction of 60%, viscose fiber with 15% and chitosan fiber with 25%, after opening, carding, laying, and then needle punching to obtain a grammage of 40g / m 2 moisture-absorbing layer.

[0047] b. Preparation of Antibacterial Polymer Solution

[0048] Add 0.5 g of ciprofloxacin hydrochloride and 19.5 g of polyvinylpyrrolidone into 80 g of deionized water, raise the temperature to 35° C. and mechanically stir for 2 hours to obtain a polyvinylpyrrolidone solution containing ciprofloxacin hydrochloride.

[0049] c, preparation of composite medical dressing

[0050] Inject the polyvinylpyrrolidone solution containing ciprofloxacin hydrochloride in the centrifugal spinning spinning pot, increase the rotating speed of spinning pot to 6000r / min at the same time with the ...

Embodiment 2

[0052] According to the above method, the preparation method of composite medical dressing comprises the following steps:

[0053] a. Preparation of hygroscopic layer

[0054] Mix calcium alginate fiber with a mass fraction of 50%, viscose fiber with 30% and chitosan fiber with 20% mass fraction, open, card, lay the net, and then obtain a grammage of 30g / m through needle punching 2 moisture-absorbing layer.

[0055]b. Preparation of Antibacterial Polymer Solution

[0056] Add 5 g of amoxicillin and 25 g of polyvinyl alcohol into 70 g of deionized water, raise the temperature to 90° C. and mechanically stir for 3 hours to obtain a polyvinyl alcohol solution containing amoxicillin.

[0057] c, preparation of composite medical dressing

[0058] Inject the polyvinyl alcohol solution containing amoxicillin into the centrifugal spinning spinning pot, and increase the spinning pot speed to 5000r / min at a rate of 50r / s at the same time, and the polyvinyl alcohol solution containing...

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Abstract

The invention relates to a preparation method of compound medical dressing, and belongs to the technical field of biomedical materials. The method comprises preparation of a moisture absorption layer,the preparation of an antibacterial polymer solution, and preparation of the compound medical dressing. According to the method, superfine polymer fiber containing antibacterial agents is rapidly prepared through a centrifugal spinning method, and the superfine polymer fiber in combination with chitosan fiber ensures that the compound medical dressing has an excellent antibacterial function; themedical dressing with excellent antibacterial, hemostatic, moisture absorption and moisture retention properties is prepared through excellent hemostatic property and moisture absorption and moistureretention properties of calcium alginate. The method is simple in technology, low in equipment requirement, convenient to operate and control, high in production efficiency and easy for industrial production.

Description

technical field [0001] The invention relates to a preparation method of a composite medical dressing, belonging to the technical field of biomedical materials. Background technique [0002] After the skin is damaged by the outside world, it will lead to a decrease in immunity, and it is easy to be infected by germs, which is not conducive to the repair and healing of the injured skin. The use of medical dressings can protect the wound very well. It can not only prevent skin dehydration, but also reduce the infection of the wound by the external environment, and provide a moist environment for skin healing. [0003] Traditional medical dressings can isolate the skin from the external environment and at the same time have a certain degree of fluid absorption. However, in the process of wound healing, traditional medical dressings do not adhere well to the skin, and tend to adhere to damaged tissues, resulting in secondary damage to the skin when changing the dressing. Theref...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L15/46A61L15/42A61L15/28D01F6/50D01F6/56D01F6/94D01F1/10
CPCA61L15/28A61L15/42A61L15/46A61L2300/232A61L2300/404D01F1/103D01F6/50D01F6/56D01F6/94C08L5/08C08L5/04
Inventor 张科王亚飞吴龙涛张小宇陈太照林勇宋宝祥沈艳王平刘欣顾绍金邓波
Owner JIANGSU YIMAO FILTER MEDIA CO LTD
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