Moisturizing and repairing composition for stimulating cellular water channel protein production

An aquaporin and cell-stimulating technology, which is applied in the field of moisturizing and repairing compositions that stimulate the production of cell aquaporin, can solve problems such as decreased hydration of the stratum corneum, delayed skin barrier repair, and impaired biosynthetic function, achieving Improves skin dryness, moisturizes and repairs the skin barrier, and improves the effect of bonding ability

Inactive Publication Date: 2018-11-20
佛山市奥姿美生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Researchers have found that the loss of AQP3 in mammalian skin can lead to dry skin, decreased stratum corneum hydration, decreased skin elasticity, delayed skin barrier repair, impaired biosynthetic function and delayed wound healing

Method used

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  • Moisturizing and repairing composition for stimulating cellular water channel protein production
  • Moisturizing and repairing composition for stimulating cellular water channel protein production
  • Moisturizing and repairing composition for stimulating cellular water channel protein production

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0046] Moisturizing Repair Cream:

[0047] The components and mass percentages of the above-mentioned moisturizing and repairing cream are:

[0048] Oil phase:

[0049]

[0050] water box:

[0051]

[0052] After emulsification, add at low temperature (45°C):

[0053]

[0054]

[0055] After heating the oil phase and the water phase to 78°C respectively, mix the two phases homogeneously for 10 minutes, stir and cool down, cool down to 45°C, add hydrolyzed pansy extract, bio-glucose gum-1, 10% ceramide 3 aqueous solution and pansy Peptide-1 copper, preservatives (preservatives are routinely used in this field), essence (essences are routinely used in this field), stirred evenly, and placed at 35°C to form a white fine and uniform paste.

[0056] The hydrolyzed pansy extract is the commercially available French Celestia Bo (SILAB) company's The solid content of the hydrolyzed pansy extract is 28-42 g / L, which is only listed here and not limited.

[0057] Sodium...

Embodiment 2

[0061] Moisturizing Repair Milk:

[0062] The components and mass percentages of the above-mentioned moisturizing and repairing milk are as follows:

[0063] Oil phase:

[0064]

[0065]

[0066] water box:

[0067]

[0068] After emulsification, add at low temperature (45°C):

[0069]

[0070] After heating the oil phase and the water phase to 78°C respectively, mix the two phases homogeneously for a few minutes, stir and cool down, then cool down to 45°C and add hydrolyzed pansy extract, bio-glucose gum-1, 10% ceramide 3 aqueous solution and tripeptide -1 Copper, preservatives, flavors, stir evenly, and place at 35°C to form a white fine and uniform emulsion.

Embodiment 3

[0072] Moisturizing Gel

[0073] The components and mass percentages of the above-mentioned moisturizing and repairing gel are:

[0074]

[0075]

[0076] The preparation method of the above-mentioned moisturizing and repairing gel comprises the following steps:

[0077] (1) Mix Stabylen 30 with PNC400 and deionized water and heat to 75°C, homogenize and dissolve to obtain a uniform gel matrix;

[0078] (2) Evenly disperse butanediol and sodium hyaluronate, add it into the gel matrix while stirring, stir and disperse evenly;

[0079] (3) Stir to lower the temperature, cool down to 45°C, mix and stir the hydrolyzed pansy extract, bio-glucose gum-1, 1% ceramide 3 aqueous solution and tripeptide-1 copper, preservative and gel matrix evenly, and deionized water add to full amount;

[0080] (5) The above-mentioned gel is inspected, and after passing the test, it is then filled to obtain the moisturizing and repairing gel.

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Abstract

The invention discloses a moisturizing and repairing composition for stimulating cellular water channel protein production. The active ingredients of the moisturizing and repairing composition are composed of hydrolyzed viola tricolor extract, sodium hyaluronate, bio-saccharide gum-1, ceramide 3 and tripeptide-1 copper. The invention further provides application of the moisturizing and repairing composition in preparation of cosmetics with moisturizing and repairing effects and cosmetics comprising the moisturizing and repairing composition. According to synergistic effects of the various active ingredients, the moisturizing and repairing composition effectively stimulates cellular water channel protein production and achieves excellent effects of moisturizing and repairing skin barrier.

Description

technical field [0001] The invention belongs to the technical field of cosmetic products, and in particular relates to a moisturizing and repairing composition for stimulating the production of cellular aquaporin. Background technique [0002] The aging of the skin is related to the water content of the skin, the hydration capacity of the stratum corneum and the barrier function. Aquaporins (AQPs) are a class of membrane-integrated proteins discovered in the 1990s that can rapidly transport water. There are currently 13 subtypes of AQP in mammals, and the distribution of different AQP subtypes has tissue, cell, and subcellular specificity. The main aquaporin distributed on the skin is AQP3, which belongs to the subfamily of aqua-glyceroporins. At present, AQP3 has been found to participate in various physiological and pathological processes, and it is closely related to the concentration of urine, the liquid balance on the airway surface, and the absorption of intestinal w...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/73A61K8/68A61K8/64A61K8/58A61Q19/00
CPCA61K8/58A61K8/64A61K8/68A61K8/73A61K8/735A61K8/9789A61K2800/5922A61Q19/00
Inventor 张彩华王进李璟如梁燕坤
Owner 佛山市奥姿美生物科技有限公司
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