Polysubstituted 3-(3-benzo[b]selenophenyl)-1H-2-aryl indole and derivative thereof and synthesis method thereof

Abstract

The invention relates to polysubstituted 3-(3-benzo[b]selenophenyl)-1H-2-aryl indole and a derivative thereof and a synthesis method thereof. A technical scheme comprising that 2-arylindoles, aromaticketones and selenium powder are converted into 3-(3-benzo[b]selenophenyl)-1H-2-aryl indole and the derivative thereof under the catalysis of iodine compounds and in an air atmosphere is adopted for the first time, and the product and the additional product thereof with stable molecular structure and excellent chemical properties are prepared; the technical scheme comprises that the 2-arylindoles,aromatic ketones and selenium powder are converted into polysubstituted 3-(3-benzo[b]selenophenyl)-1H-2-aryl indole and the derivative thereof under the catalysis of iodine compounds and in an air atmosphere, the reaction raw materials are cheap and easy to obtain and have no need of pretreatment, and the atomic economy of the reaction is high; the reaction only needs to use cheap iodine compounds, environmental pollution is reduced, the raw materials are saved, and the reaction cost is reduced; the whole reaction system is simple, the reaction conditions are mild, the number of reaction equipment is small, experiment operation is simple and safe, and material sources are wide.

Description

technical field [0001] The invention relates to a multi-substituted 3-(3-benzo[b]selenophenyl)-1H-2-arylindole and a derivative thereof and a synthesis method thereof, belonging to the technical field of organic compound synthesis. Background technique [0002] 3-(3-Benzo[b]selenophenyl)-1H-2-arylindole and its derivatives are an important class of aromatic heterocyclic compounds, which contain large conjugated systems and strong molecular Internal electron transfer, this special rigid fused ring structure enables 3-(3-benzo[b]selenophenyl)-1H-2-arylindole compounds to exhibit many unique properties and biological activities. , dyes, medicine, supramolecular recognition and many other fields have potential applications. The existing methods for synthesizing such compounds have the disadvantages of complicated synthesis steps, mostly using organic selenium compounds or metal selenium compounds as the selenium source, which can only be completed by multi-step synthesis proces...

AI Technical Summary

Problems solved by technology

The existing methods for synthesizing such compounds have complex synthesis steps, mostly using organic selenium compounds or metal selenium compounds as selenium sources, which can only be completed by multi-step synthesis processes, and often need to add transition metal catalysts, chemically equivalent metal oxidants, etc.

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