Check patentability & draft patents in minutes with Patsnap Eureka AI!

Cyclodextrin modified gold nanoparticles and preparation method and application thereof

A gold nanoparticle and cyclodextrin technology, which is applied in measuring devices, instruments, and material analysis through electromagnetic means, can solve problems affecting applications, achieve simple methods, simple preparation methods, and good application prospects

Inactive Publication Date: 2019-01-04
LIAONING UNIVERSITY
View PDF3 Cites 2 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

AuNPs have good electrical conductivity, large specific surface area and excellent catalytic performance, however, AuNPs without any chemical modification tend to agglomerate, seriously affecting their application in electrochemical sensing

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Cyclodextrin modified gold nanoparticles and preparation method and application thereof
  • Cyclodextrin modified gold nanoparticles and preparation method and application thereof
  • Cyclodextrin modified gold nanoparticles and preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0023] Example 1 Preparation method of β-CD@AuNPs

[0024] (1) The preparation method is as follows

[0025] 1. Preparation of β-CD@AuNPs

[0026] In 35 mL of ultrapure water, add 5 mL of 0.1 mol / L, PBS at pH=7.00, 1 mL of 0.01 mol / L, HAuCl 4 and 10mL 0.01mol / L, β-CD and mix well. Then heated in an oil bath at 100 °C, the solution gradually changed from light yellow to bright red, purple, and finally wine red, indicating that gold nanoparticles had been formed. The product was centrifuged at 10,000rpm for 10min and washed twice with water to obtain the target product β-CD@AuNPs, which was stored in a low-temperature environment at 4°C.

[0027] 2. Preparation of unmodified AuNPs

[0028] In 20mL of ultrapure water pre-cooled at 4°C, add 0.5mL of 1% chloroauric acid solution, and then add 0.2mol / L of K 2 CO 3 Solution 0.1mL, under the condition of stirring, quickly add 0.5mg / mL sodium borohydride solution 0.5mL in batches until wine red color appears, the product is centr...

Embodiment 2

[0032] Example 2 Detection performance of β-CD@AuNPs modified electrode

[0033] (1) Preparation of β-CD@AuNPs modified electrode

[0034] 1. Electrode pretreatment

[0035] Use 0.1, 0.3, 0.05μm A1 2 o 3 Polish the glassy carbon electrode. Then, ultrasonic cleaning was performed with acetone, ethanol, and ultrapure water for 1 min in sequence. The glassy carbon electrode is used as the working electrode, the Ag / AgCl electrode is used as the reference electrode, and the platinum wire is used as the counter electrode. - 3 mol / L K 3 Fe(CN) 6 The electrochemical cyclic voltammetry (CV) test was carried out in the 1mol / L KCl solution, and the scanning range was 0.3-0.8V (vs.Ag / AgCl). After the test, the electrodes were cleaned with ultrapure water and dried with high-purity nitrogen gas for later use.

[0036] 2. Preparation of modified electrode β-CD@AuNPs

[0037] The β-CD@AuNPs prepared in Example 1 was dissolved in water, and 5 μL of the β-CD@AuNPs aqueous solution wi...

Embodiment 3

[0048] Example 3 Catalytic detection performance of β-CD@AuNPs modified electrode for bisphenol A

[0049] (1) Detection performance of β-CD@AuNPs modified electrode for different concentrations of BPA

[0050] The β-CD@AuNPs modified electrode prepared in Example 2 (1) was used as the working electrode, the Ag / AgCl electrode was used as the reference electrode, and the platinum electrode was used as the auxiliary electrode. Add 0.2 (a) to nitrogen-saturated PBS, respectively, 0.3, 1.3, 2.3, 3.3, 4.3, 6.3, 8.3, 10.3, 15.3 (j) μmol / L of bisphenol A, the test results are as follows Figure 5 As shown, when the concentration of BPA in the supporting electrolyte gradually increases, the oxidation peak current of the modified electrode will gradually increase, which proves that the modified electrode has good catalytic recognition performance for BPA.

[0051] (2) Effect of interfering substances on the detection performance of β-CD@AuNPs modified electrodes

[0052] The β-CD@AuN...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
Particle sizeaaaaaaaaaa
Login to View More

Abstract

The invention relates to cyclodextrin modified gold nanoparticles and a preparation method and application thereof. The technical scheme includes that beta cyclodextrin modified gold nanoparticles (beta-CD@AuNPs) are prepared and immobilized on the surface of a glassy carbon electrode (GCE) to construct an electrochemical sensor beta-CD@AuNPs / GCE having stability and conductivity that gold nanoparticles (AuNPs) have and subject-object recognition characteristics that beta-cyclodextrin (beta-CD) has. The modified electrode is used for detecting bisphenol A (BPA) content, presents good electrocatalytic activity to BPA and has potential application prospect in detecting BPA in actual samples.

Description

technical field [0001] The invention belongs to the field of composite materials, and in particular relates to a cyclodextrin-modified gold nanoparticle, a preparation method thereof and a method for detecting bisphenol A. Background technique [0002] Bisphenol A (BPA), used industrially to synthesize materials such as polycarbonate (PC) and epoxy resins, is an endocrine disruptor that mimics the body's own hormones and can lead to negative health effects. In recent years, because BPA is a key monomer in the production of polycarbonate (PC) plastics, which are widely used in the manufacture of a variety of common products including baby bottles, water bottles, medical and dental equipment, eyeglasses and household electronics, it has caused daily Concerns about the effects of bisphenol A in humans have intensified due to high levels of BPA intake. Electrochemical detection methods have great potential in environmental monitoring due to their advantages of rapidity, easy mi...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): G01N27/30
CPCG01N27/308
Inventor 吴抒遥郝金玉吴阳孙颖王雨露宋溪明
Owner LIAONING UNIVERSITY
Features
  • R&D
  • Intellectual Property
  • Life Sciences
  • Materials
  • Tech Scout
Why Patsnap Eureka
  • Unparalleled Data Quality
  • Higher Quality Content
  • 60% Fewer Hallucinations
Social media
Patsnap Eureka Blog
Learn More

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2025 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com