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Ointment for treating leukoderma and preparation method of ointment

A technology of vitiligo and cream, applied in the field of medicine, can solve the problems of single treatment method, poor treatment effect, no combination of diagnosis and treatment, etc., achieve broad market prospects, improve promotion effect, and reduce side effects

Inactive Publication Date: 2019-01-22
何凤姣
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Traditional Chinese medicine believes that the depigmentation of patients with vitiligo is related to the meridians of the liver, kidney, spleen and lung. However, the existing vitiligo creams are treated by adding western medicine. The treatment method is single, and there is no combination of traditional Chinese medicine and western medicine. Difference

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] In an embodiment of the present invention, a cream for treating vitiligo comprises the following raw materials in parts by weight: 0.08 part of beclomethasone dipropionate, 61 parts of vitamin B, 0.2 part of pregelatinized starch, 0.1 part of L-tartaric acid, carboxymethyl starch 0.2 parts of sodium, 0.05 parts of methoxsalen, 0.1 parts of calamine powder, 0.3 parts of maltodextrin, 0.1 parts of methylcobalamin, 0.15 parts of glycyrrhizin, 0.06 parts of vitamin D3 derivatives, 0.08 parts of dimethyl sulfoxide, white 0.4 part of petrolatum, 0.01 part of calcineurin inhibitor, and 2 parts of traditional Chinese medicine composition.

[0021] Wherein, the vitamin D3 derivative is calcipotriol.

[0022] The calcineurin inhibitor is tacrolimus.

[0023] The traditional Chinese medicine composition is mixed with psoralen, castor bean, smilax and tribulus according to the mass ratio of 1:1:2:1.

[0024] In the present embodiment, the preparation method of the cream for the t...

Embodiment 2

[0030] In an embodiment of the present invention, a cream for treating vitiligo comprises the following raw materials in parts by weight: 0.09 parts of beclomethasone dipropionate, 1.5 parts of vitamin B6, 0.4 parts of pregelatinized starch, 0.15 parts of L-tartaric acid, carboxymethyl Starch sodium 0.3 part, methoxsalen 0.1 part, calamine powder 0.2 part, maltodextrin 0.4 part, methylcobalamin 0.15 part, glycyrrhizin 0.2 part, vitamin D3 derivative 0.08 part, dimethyl sulfoxide 0.1 part , 0.5 parts of white petrolatum, 0.015 parts of calcineurin inhibitor, and 3 parts of traditional Chinese medicine composition.

[0031] Wherein, the vitamin D3 derivative is tacalcitol.

[0032] The calcineurin inhibitor is tacrolimus.

[0033] The traditional Chinese medicine composition is mixed with psoralen, castor bean, smilax and tribulus according to the mass ratio of 1:1:2:1.

[0034] In the present embodiment, the preparation method of the cream for the treatment of vitiligo, the s...

Embodiment 3

[0040] In an embodiment of the present invention, a cream for treating vitiligo comprises the following raw materials in parts by weight: 0.1 part of beclomethasone dipropionate, 62 parts of vitamin B, 0.5 part of pregelatinized starch, 0.2 part of L-tartaric acid, carboxymethyl starch 0.4 parts of sodium, 0.15 parts of methoxsalen, 0.3 parts of calamine powder, 0.5 parts of maltodextrin, 0.2 parts of methylcobalamin, 0.25 parts of glycyrrhizin, 0.09 parts of vitamin D3 derivatives, 0.12 parts of dimethyl sulfoxide, white 6 parts of petrolatum, 0.02 parts of calcineurin inhibitor, and 4 parts of traditional Chinese medicine composition.

[0041] Wherein, the vitamin D3 derivative is calcitriol.

[0042] The calcineurin inhibitor is pimecrolimus.

[0043] The traditional Chinese medicine composition is mixed with psoralen, castor bean, smilax and tribulus according to the mass ratio of 1:1:2:1.

[0044] In the present embodiment, the preparation method of the cream for the tr...

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Abstract

The invention discloses ointment for treating leukoderma, and relates to the technical field of medicines, for solving the problem that the existing ointment is single in treatment method and poor ineffect. The ointment is prepared from the following raw materials: beclometasone dipropionate, vitamin B, pregelatinized starch, L-tartaric acid, sodium carboxymethyl starch, methoxsalen, calamine powder, maltodextrin, mecobalamine, glycyrrhizin, vitamin D derivatives, dimethyl sulfoxide, albolene, a calcineurin inhibitor and a traditional Chinese medicinal composition. The invention further discloses a preparation method of the ointment for treating leukoderma. For the prepared ointment, the nutritional ingredients and the western medicinal ingredients are combined for realizing external use,the transdermal absorption is realized, the local treatment is realized, the local application influences the whole body, meanwhile, through the combination of the western medicinal ingredients and the traditional Chinese medicinal ingredients, the functions of dispelling wind, clearing heat and promoting diuresis, dispersing stagnated liver qi to relieve depression, and nourishing the liver andthe kidney can be further achieved, the effects of hormone can be promoted, the side effects of hormone can be alleviated, moreover, the promoting effect of ultraviolet irradiation for melanogenesis is improved, and therefore, the ointment has the wide market prospect.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a cream for treating vitiligo and a preparation method thereof. Background technique [0002] Vitiligo is divided into two types: complete leukoplakia and incomplete leukoplakia, and is a common and multiple pigmented skin disease. The disease is characterized by localized or generalized depigmentation to form leukoplakia. It is an acquired localized or generalized skin depigmentation disease. It is a common skin disease that affects appearance. It is easy to diagnose but difficult to treat. Traditional Chinese medicine calls it "vitiligo" or "white bark wind". Vitiligo is acquired localized white patches due to depigmentation of the skin, which makes the local skin appear white. In medicine, this kind of lesion is usually called depigmentation. The disease occurs all over the world, and India has the highest incidence rate. In my country, tens of millions of people are affec...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/90A61K36/896A61K9/06A61K47/36A61P17/00A61K33/30A61K31/714A61K31/704A61K31/593A61K31/573A61K31/4415A61K31/436A61K31/37
CPCA61K31/436A61K9/06A61K31/37A61K31/4415A61K31/573A61K31/593A61K31/704A61K31/714A61K33/30A61K36/185A61K36/47A61K36/487A61K36/896A61K36/90A61K47/36A61P17/00A61K2300/00
Inventor 何凤姣
Owner 何凤姣