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Composition containing plant antiallergenic ingredient and its preparation method

A composition and plant technology, applied in the direction of medical preparations containing active ingredients, drug combinations, skin care preparations, etc., can solve the problems of lower overall allergy rate, low allergy rate of antisensitizers, and inability to coexist stably, achieving Enhanced skin barrier function, long-lasting anti-allergic effect, and enhanced immunity

Inactive Publication Date: 2019-01-25
SHANGHAI YUEMU COSMETICS
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Mask is currently one of the most consumed varieties in the skin care market. Compared with other dosage forms, mask has a large amount of skin absorption and fast absorption, so the effect is more prominent. It is widely used in anti-aging, whitening, acne, repair and other functional care products. But also because of its large absorption capacity, fast and semi-closed absorption state, it is the most likely to cause allergies among all dosage forms. Therefore, how to reduce the allergies of facial masks has practical significance for the development of the industry.
[0003] At present, for the allergies of facial masks, the conventional thinking is to add anti-sensitivity agents according to the thinking of ordinary daily chemical products, such as early bisabolol, dipotassium glycyrrhizinate and other synthetic or semi-synthetic raw materials, as well as the popular plant extracts or Raw materials from fermentation sources, but in facial mask products, anti-allergic agents are often added and the allergy rate is still high, and there are often anti-allergic agents added with low allergies. Individuals who were not allergic are allergic
[0004] The synergistic combination of antisensitizers has become the most feasible direction to solve the problem, but often the antisensitizers from different sources have compatibility problems, including no synergistic effect or even reduced efficiency, and problems such as inability to coexist stably

Method used

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  • Composition containing plant antiallergenic ingredient and its preparation method
  • Composition containing plant antiallergenic ingredient and its preparation method
  • Composition containing plant antiallergenic ingredient and its preparation method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] A plant anti-allergic composition, its preparation method is as follows:

[0029] (1) Weigh the following components: gentian anti-irritant factor 80kg, black soybean fermentation liquid 15kg, highland barley dextran aqueous solution 2kg, mix well; add 0.3% chitosan solution (1% concentration), stir well;

[0030] (2) Put it into a high and low temperature incubator for aging. The aging conditions are set at -10°C for low temperature and 60°C for high temperature, and the alternating cycle is 24h / time, alternating 5 times.

[0031] (3) After aging, centrifuge at 18,000 rpm in a straight-tube centrifuge until clarified, take the supernatant and filter it with a 2 μm ceramic membrane, and then perform ultrafiltration on the filtrate. Add an equal amount of 50% butanediol solution, continue ultrafiltration until the quality of the permeate is equal to the mass of the original solution, and take the permeate.

Embodiment 2

[0033] A plant anti-allergic composition, its preparation method is as follows:

[0034] (1) Weigh the following components: gentian anti-irritant factor 90kg, black soybean fermentation liquid 5kg, highland barley dextran aqueous solution 5kg, mix well; add 0.1% chitosan solution (1% concentration), stir well;

[0035] (2) Put it into a high and low temperature incubator for aging. The aging conditions are set at -20°C for low temperature and 50°C for high temperature, and the alternating cycle is 36h / time, alternating 3 times.

[0036] (3) After aging, centrifuge at 18,000 rpm in a straight-tube centrifuge until clarified, take the supernatant and filter it with a 2 μm ceramic membrane, then perform ultrafiltration on the filtrate, and use a filter membrane with a molecular weight cut-off of 1500kDa to ultrafilter until the remaining 30% of the retentate is replenished. Add an equal amount of 50% butanediol solution, continue ultrafiltration until the quality of the permeate...

Embodiment 3

[0038] A plant anti-allergic composition, its preparation method is as follows:

[0039] (1) Weigh the following components: gentian anti-irritant factor 85kg, black soybean fermentation broth 10kg, highland barley dextran aqueous solution 2.5kg, mix well; add 0.2% chitosan solution (1% concentration), stir well;

[0040] (2) Put it into a high and low temperature incubator for aging. The aging conditions are set at -15°C for low temperature and 55°C for high temperature, and the alternating cycle is 30h / time, alternating 4 times.

[0041] (3) After aging, centrifuge at 18,000 rpm in a straight-tube centrifuge until clarified, take the supernatant and filter it with a 2 μm ceramic membrane, then perform ultrafiltration on the filtrate, and use a filter membrane with a molecular weight cut-off of 1300kDa to ultrafilter until the remaining 30% of the retentate is replenished. Add an equal amount of 50% butanediol solution, continue ultrafiltration until the quality of the permea...

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Abstract

The invention discloses a plant anti-allergy composition, which comprises the following components in parts by mass: gentian anti-stimulating factor 80-90 parts, black soybean fermentation broth 5-15part, and highland barley dextran aqueous solution 2-5 parts. Using the strong anti-allergic, anti-inflammatory and anti-irritant effect of gentian anti-irritant factor to eliminate the skin allergy and other symptoms, Japanese black soybean fermentation broth fermented with lactobacillus acid provides nutrients and probiotic growth promoting ingredients for skin, adjust the microflora balance andPH value of skin, cooperate with anti-allergy and enhance the immunity of skin, release gentian anti-irritation factor slowly by using the film-forming effect of middle molecular barley dextran, makethe anti-allergy effect lasting, can also reduce abnormal allergy phenomenon of individual normal individual, the whole long-term use can also make the skin barrier function strengthen.

Description

technical field [0001] The invention relates to the field of cosmetics, in particular to a composition containing plant anti-allergic ingredients and a preparation method thereof. Background technique [0002] Mask is currently one of the most consumed varieties in the skin care market. Compared with other dosage forms, mask has a large amount of skin absorption and fast absorption, so the effect is more prominent. It is widely used in anti-aging, whitening, acne, repair and other functional care products. But also because of its large absorption, fast absorption and semi-closed absorption state, it is the most likely to cause allergies among all dosage forms. Therefore, how to reduce the allergies of facial masks has practical significance for the development of the industry. [0003] At present, for the allergies of facial masks, the conventional thinking is to add anti-sensitivity agents according to the thinking of ordinary daily chemical products, such as early bisabolo...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/73A61P37/08A61Q19/00
CPCA61K8/73A61K2800/75A61K2800/85A61Q19/005A61K8/9789A61P37/08
Inventor 胡家逢李继德张目梁活玲
Owner SHANGHAI YUEMU COSMETICS