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Medical cold compress gel for treating eczematous dermatitis of children and preparation method of medical cold compress gel

A technology for dermatitis, eczema and children, which is applied in the field of preparation of medical cold compress gel, can solve problems such as endocrine system disorder, influence on growth and development, and gastrointestinal discomfort, and achieve the effects of reducing side effects, alleviating inflammation, and alleviating itching.

Inactive Publication Date: 2019-02-15
曲沃李时珍医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] In order to overcome the deficiencies in the prior art, one of the purposes of the present invention is to provide a medical cold compress gel for the treatment of children's dermatitis eczema, to solve the inconvenient use, ubiquitous drug resistance and Side effects, long-term use can also cause endocrine system disorders, affected growth and development, irritability, gastrointestinal discomfort, and decreased concentration

Method used

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  • Medical cold compress gel for treating eczematous dermatitis of children and preparation method of medical cold compress gel
  • Medical cold compress gel for treating eczematous dermatitis of children and preparation method of medical cold compress gel
  • Medical cold compress gel for treating eczematous dermatitis of children and preparation method of medical cold compress gel

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034]Preparation steps: Weigh 2g of sun-dried Fangfeng, 20g of lovage, 4g of coix seed, 2g of curcuma, 3g of mint, 1g of perilla leaf and 24g of Tripterygium wilfordii to form component A. Weigh 20g of Xu Changqing, 2g of borneol, 4g of fennel and 5g of cardamom to form component B. Weigh 18g of Schisandra chinensis, 8g of Shijunzi, 6g of Tujingpi and 21g of realgar to form component C. Grind components A, B and C into powder with a traditional Chinese medicine grinder, pass through a 10-mesh sieve, and set aside.

[0035] Preparation of the first extraction extract step: transfer component A to a round-bottomed flask, add 200ml of ether to the round-bottomed flask and mix well, transfer the round-bottomed flask to a constant temperature water bath at 45°C for rotation and reflux extraction for 2.5 hours . After the reflux extraction process ends, the separatory funnel is left standing to separate the medicinal residues and ether, and the ether is transferred to a rotary eva...

Embodiment 2

[0041] Preparation steps: Weigh 4g of sun-dried Fangfeng, 10g of lovage, 12g of coix seed, 7g of curcuma, 8g of mint, 6g of perilla leaf and 16g of Tripterygium wilfordii to form component A. Weigh 8g of Xu Changqing, 10g of borneol, 9g of fennel and 12g of cardamom to form component B. Weigh 8g of Schisandra chinensis, 12g of Shijunzi, 8g of Tujingpi and 16g of realgar to form component C. Grind components A, B and C into powder with a traditional Chinese medicine grinder, pass through a 20-mesh sieve, and set aside.

[0042] Preparation of the first extraction extract step: transfer component A to a round-bottomed flask, add 260ml of ether to the round-bottomed flask and mix well, transfer the round-bottomed flask to a constant temperature water bath at 42°C for rotation and reflux extraction for 2.2 hours . After the reflux extraction process ends, the separatory funnel is left standing to separate the medicinal residues and ether, and the ether is transferred to a rotary ...

Embodiment 3

[0048] Preparation steps: Weigh 5g of sun-dried Fangfeng, 12g of lovage, 10g of coix seed, 5g of curcuma, 7g of mint, 5g of perilla leaf and 13g of Tripterygium wilfordii to form component A. Weigh 11g of Xu Changqing, 7g of borneol, 7g of fennel and 10g of cardamom to form component B. Weigh 12g of Schisandra chinensis, 15g of Shijunzi, 10g of Tujingpi and 13g of realgar to form component C. Grind components A, B and C into powder with a traditional Chinese medicine grinder, pass through a 20-mesh sieve, and set aside.

[0049] Preparation of the first extraction extract step: transfer component A to a round-bottomed flask, add 320ml of ether to the round-bottomed flask and mix well, transfer the round-bottomed flask to a constant temperature water bath at 39°C for rotation and reflux extraction for 2 hours. After the reflux extraction process ends, the separatory funnel is left standing to separate the medicinal residues and ether, and the ether is transferred to a rotary ev...

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Abstract

The invention discloses medical cold compress gel for treating eczematous dermatitis of children. The medical cold compress gel is prepared from non-woven fabric, release paper attached to the non-woven fabric as well as plant extracts, sodium hyaluronate, carbopol and hydrogel which are applied to the non-woven fabric by coating, wherein the active extracts are extracts of radix saposhnikoviae, radix angelicae pubescentis, semen coicis, rhizoma curcumae, herba menthae, perilla leaves, common threewingnut root, radix cynanchi paniculati, borneol, fennel, fructus amomi rotundus, fructus schizandrae, fructus quisqualis, cortex pseudolaricis and realgar; a weight ratio of the plant extracts, sodium hyaluronate, carbopol and hydrogel is 100:(1-10):(1-10):(50-500). The invention further discloses a preparation method of the medical cold compress gel for treating eczematous dermatitis of children. The medical cold compress gel for treating eczematous dermatitis of children can effectively relieve scytitis or symptoms such as pruritus, red ache, skin eruptions and the like caused by eczema and reduce level of inflammatory factors in vivo.

Description

technical field [0001] The invention relates to the field of pediatric medical products, in particular to a medical cold compress gel for treating children's dermatitis and eczema, and also relates to a preparation method for preparing the above-mentioned medical cold compress gel for treating children's dermatitis and eczema. Background technique [0002] Dermatitis refers to a general term for skin inflammatory diseases caused by various internal and external infections or non-infectious factors. It is not an independent disease. Its etiology and clinical manifestations are complex and diverse, and it recurs repeatedly, making clinical treatment difficult. Eczema (Eczema) is a skin inflammatory reaction with severe itching caused by various internal and external factors. Divided into acute, subacute and chronic stages. In the acute phase, it tends to exudate, while in the chronic phase, it is infiltrating and hypertrophic. Some patients directly show as chronic eczema. ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/70A61P17/00A61P17/04A61K31/045A61K33/36
CPCA61K9/7061A61K31/045A61K33/36A61K36/15A61K36/185A61K36/232A61K36/235A61K36/238A61K36/27A61K36/37A61K36/534A61K36/535A61K36/57A61K36/79A61K36/8994A61K36/9064A61K36/9066A61K2236/331A61K2236/333A61K2236/35A61P17/00A61P17/04A61K2300/00
Inventor 刘小俊
Owner 曲沃李时珍医药科技有限公司
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