Biopolymer nanosphere containing nicotinamide mononucleotide (NMN) and preparation method and application thereof

Abstract

The invention discloses a biopolymer nanosphere containing nicotinamide mononucleotide (NMN). The biopolymer nanosphere comprises a biopolymer carrier and NMN dispersed on the biopolymer carrier. Thebiopolymer carrier is made of a polymer fiber aggregate, fibrous skeletons of the polymer fiber aggregate constitute a three-dimensional interpenetrating network structure through arrangement modes ofunordered arrangement, cross arrangement, curling arrangement and the like, thus the NMN is protected, the problem that the NMN is prone to being decomposed after encountering light or being oxidizedis solved, the preservation time of effective components of the NMN is prolonged, and the preservation difficulty of the effective components of the NMN is lowered. The invention further discloses apreparation process of the nanosphere, a biopolymer material with the moderate chain length is obtained after physical modification, spherical particles are easy to form, the cellular three-dimensional interpenetrating network structure is constituted, and NMN small molecules are loaded on the inner surface and the outer surface of the network structure advantageously. The nanosphere can be used for preparing preparations such as tablets, particles, capsules or soft capsules and serves as human body health protection or pet therapy drug / functional food.

Description

technical field [0001] The invention belongs to the technical field of health care products, and in particular relates to a biopolymer nanosphere containing NMN, a preparation and a preparation method and application thereof. Background technique [0002] From a biological point of view, aging is a spontaneous and inevitable process of organisms over time. It is a complex natural phenomenon. With the aging of the whole body and the aging of the body, many health problems will arise, seriously affecting People's quality of life, in order to solve the above problems, drugs aimed at delaying aging, improving health or quality of life have obtained extensive research and popularization in recent years. [0003] The biological substance of nicotinamide mononucleotide (NMN) has the effect of increasing physical function and intellectual surface without side effects. NMN plays an important role in the energy generation of human cells, and it participates in intracellular NAD (nicot...

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Problems solved by technology

[0004] However, NMN has the problem of chemical instability and needs to be ready-to-use. Although the central activation and stimulation characteristics of this biomolecule were determined 50 years ago, due to its highly sensitive and unstable molecular characteristics, such as light It is very sensitive to oxygen and oxygen, which makes it difficult to be widely used, and the existing oral preparations containing NMN have a low absorption rate in the human body. Therefore, it is urgent to find a NMN material with stable production and high absorption efficiency.

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