Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Method for synthesizing dual-esterified 3,4,5-trihydroxybenzoxy bagasse xylan benzoate

A technology of trihydroxybenzoic acid and benzoate, applied in the field of fine chemicals, can solve the problems of unsatisfactory anti-HIV effect and low degree of substitution in general, and achieve the effects of improved surface activity and easy control of synthesis process conditions

Inactive Publication Date: 2019-03-01
GUILIN UNIVERSITY OF TECHNOLOGY
View PDF2 Cites 4 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Since the monoesterification of xylan only introduces a biologically active group, the degree of substitution is generally low, and the resulting anti-HIV effect is not ideal

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Method for synthesizing dual-esterified 3,4,5-trihydroxybenzoxy bagasse xylan benzoate
  • Method for synthesizing dual-esterified 3,4,5-trihydroxybenzoxy bagasse xylan benzoate
  • Method for synthesizing dual-esterified 3,4,5-trihydroxybenzoxy bagasse xylan benzoate

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0043] (1) Dry 6 g of bagasse xylan in a constant-temperature vacuum oven at 60° C. for 24 hours to constant weight to obtain dry-based bagasse xylan.

[0044] (2) Add 8g of 3,4,5-trihydroxybenzoic acid into a 250mL four-necked flask, and add 18mL of analytically pure acetic anhydride and 15mL of analytically pure pyridine, control the temperature of the ice bath at 5°C, and react under stirring for 6 Hour. Add 30 mL of hydrochloric acid solution with a mass fraction of 25%, and stir evenly to obtain a crude product of 3,4,5-triacetylbenzoic acid.

[0045](3) The crude product of 3,4,5-triacetylbenzoic acid obtained in step (2) was filtered with suction, and the precipitate was fully washed with 15 mL of distilled water for 3 times, then filtered with suction, and the filter cake was sent to a vacuum constant temperature drying oven at 50°C for 24 hours to dry. Constant weight, in 3,4,5-triacetylbenzoic acid.

[0046] (4) Take 6 g of 3,4,5-triacetylbenzoic acid obtained in s...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention discloses a method for synthesizing dual-esterified 3,4,5-trihydroxybenzoxy bagasse xylan benzoate. The method comprises the steps: subjecting 3,4,5-triacetyl benzoyl chloride, which isproduced through subjecting 3,4,5-trihydroxybenzoic acid to acetylation and acyl chlorination and serves as an esterifying agent, to an esterification reaction with bagasse xylan in a N,N-dimethylformamide solvent, so as to synthesize bagasse xylan 3,4,5-trihydroxy benzoate; then, carrying out a second-step esterification reaction by taking benzoic acid as an esterifying agent and triethylamine asa catalyst, and synthesizing a dual-esterified 3,4,5-trihydroxybenzoxy bagasse xylan benzoate derivative in a dichloromethane solvent. According to the method, on the basis of unique bioactivity of xylan esterified derivatives, through introducing two kinds of active groups, the product has the advantages that the bioactivity of xylan is improved, and meanwhile, the range of application of the xylan derivatives in the fields of medicine, biology, functional materials and the like is widened.

Description

technical field [0001] The invention relates to the field of fine chemicals and provides a method for synthesizing diesterized 3,4,5-trihydroxybenzoic acid-based bagasse xylan benzoate. Background technique [0002] Bagasse is an industrial residue of the sugar industry in Guangxi, and its rich xylan can be transformed into high value-added products through physical and chemical modification. The monoesterification modification of xylan is one of the commonly used modification methods of xylan. After xylan is esterified, its product not only improves and improves in structure and thermal stability, but also enhances the antioxidant capacity. , anti-HIV, anti-tumor, anti-virus and other biological activities. [0003] The anti-HIV activity of xylan can be enhanced by esterification of gallic acid with strong biological activity, namely 3,4,5-trihydroxybenzoic acid, with bagasse xylan. Since the monoesterification of xylan only introduces a biologically active group, the deg...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): C08B37/00
CPCC08B37/0057
Inventor 李和平柴建啟耿恺张淑芬杨莹莹武晋雄张俊龚俊
Owner GUILIN UNIVERSITY OF TECHNOLOGY
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com