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Medical polysilicone, ozone oil and petrolatum dressing and wound surface nursing paste based on dressing

A technology of vaseline and ozone oil, which is applied in the field of wound care stickers and medical silicone ozonated oil vaseline dressings, can solve the problems of secondary injury and infection of the wound surface, lack of clinical application conditions, and lack of antibacterial and anti-inflammatory effects, etc. The effect of collagen fiber synthesis, good air permeability, good chemical stability and physiological inertia

Pending Publication Date: 2019-04-02
郑州和济生物科技股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is aimed at the fact that the existing medical dressings generally do not have antibacterial and anti-inflammatory effects, which may easily cause secondary injury and infection of the wound surface during use and affect wound healing, while the existing ozone oil products do not have clinical application conditions. And for the limited effect of promoting wound healing, a medical polysilicone ozone oil vaseline dressing and a wound care patch based on the dressing are provided

Method used

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  • Medical polysilicone, ozone oil and petrolatum dressing and wound surface nursing paste based on dressing
  • Medical polysilicone, ozone oil and petrolatum dressing and wound surface nursing paste based on dressing
  • Medical polysilicone, ozone oil and petrolatum dressing and wound surface nursing paste based on dressing

Examples

Experimental program
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Effect test

Embodiment 1-8

[0071] The following table 1 is a list of raw material component contents of the Chinese medicine polysilicone ozone oil vaseline dressing in Examples 1-8 of the present invention. The medical silicone ozonated oil vaseline dressing of Examples 1-8 was prepared according to the following formula and preparation method.

[0072] The medical polysilicone ozone oil vaseline dressing of the present invention comprises the following raw materials in parts by weight: 5-20 parts of polydimethylsiloxane crosslinked polymer, 30-70 parts of ozone oil, 10-30 parts of vaseline, shell 5-15 parts of polysaccharide aqueous solution, 5-15 parts of sodium alginate aqueous solution; the mass fraction of the chitosan aqueous solution is 1-4%, and the mass fraction of the sodium alginate aqueous solution is 1-4%.

[0073] The preparation method of medical polysilicone ozone oil vaseline dressing of the present invention may further comprise the steps:

[0074] (1) Mix chitosan aqueous solution a...

Embodiment 9-16

[0081]For the convenience of observing the stability of the wound care patch of the present invention and the effect of clinical trials on animals and humans, Examples 9-16 correspond to the medical polysilicone ozone oil Vaseline dressings prepared in Examples 1-8 to make conventional wounds Nursing paste, the conventional wound care paste of the embodiment of the present invention 9-16, is to soak 1- After 3 hours (preferably 2 hours), take out, subpackage, and sterilize. Specific examples 9-11 are obtained by soaking medical gauze respectively in the medical polysilicone ozone oil vaseline dressing prepared in Examples 1-3 for 2 hours; The medical polysilicone ozone oil Vaseline dressing prepared in 4-6 was prepared in 3 hours; Examples 15 and 16 were respectively soaked in the medical polysilicone ozone oil Vaseline dressing prepared in Examples 7 and 8 by using medical non-woven fabrics Made in 1 hour.

[0082] In order to verify the in vitro antibacterial test and stab...

Embodiment 17

[0188] see Figure 1-Figure 6 , a wound care patch based on medical polysilicone ozone oil vaseline dressing (hereinafter referred to as medical polysilicone ozone oil vaseline wound care patch), comprising a backing layer 1 and a sealing film 2, in particular: on the backing layer 1 and the sealing film 2 are also provided with a dressing base material layer 3, and the dressing base material layer 3 and the backing layer 1 are glued and sealed around to form a drug delivery interlayer 4; the backing layer 1 protrudes upwards by 1~ 5mm (concretely protruding 2mm in this embodiment), there are several drug administration holes 5 on the dressing base material layer 3, and the adhesive layer 6 is coated with the adhesive layer 6 around the dressing base material layer 3 to fit and seal with the sealing film 2; the backing One end of the layer 1 is pre-embedded with a drug delivery hose 7, the drug delivery hose 7 extends out of the backing layer 1 and is provided with a sealing j...

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Abstract

The invention discloses medical polysilicone, ozone oil and petrolatum dressing and wound surface nursing paste based on the dressing. The dressing comprises the following raw materials in parts by weight of 5-20 parts of polydimethylsiloxane cross-linked polymers, 30-70 parts of ozone oil, 10-30 parts of petrolatum, 5-15 parts of a chitosan aqueous solution and 5-15 parts of a sodium alginate aqueous solution. Besides, the invention further provides the wound surface nursing paste based on the dressing. According to the wound surface nursing paste, a conventional way of clinical wound surfacenursing is broken through, under the situation of applying the paste once, medicine administration can be repeatedly performed on the wound surface, enormous convenience is brought for the work of medical personnel, and the workload of the medical personnel is alleviated. The ozone oil added in the medical polysilicone, ozone oil and petrolatum dressing has the effects of resisting bacteria and diminishing inflammation, and can effectively prevent wound skin from being infected; the petrolatum has the effect of preventing skin from adhesion; and the polysilicone has the effects of promoting repairing of wound skin and preventing the wound skin from scabbing, and besides, has good effects of warming skin, and repairing the wound skin caused by burning, scalding, scraping, surgical operation and the like.

Description

technical field [0001] The invention relates to the technical field of medical dressings, in particular to a medical polysilicone ozonated oil vaseline dressing and a wound care patch based on the dressing. The polysilicone ozonated oil vaseline dressing of the present invention can prevent the dressing from sticking to the skin wound surface, and it has antibacterial Anti-inflammatory, lubricating, non-adhesive to wounds, breathable and moisturizing, promotes granulation growth, promotes wound healing and prevents scabs. Background technique [0002] Clinically, various skin wounds are often encountered, such as wounds caused by burns, scalds, abrasions and surgical operations, skin grafted areas and skin grafted areas, etc. Currently, it is generally necessary to deal with these different types of skin wounds Various isolation dressings are used to isolate the wound surface from other dressings. The commonly used isolation dressings are made of insulating mesh materials or...

Claims

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Application Information

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IPC IPC(8): A61L26/00A61L15/18A61L15/46A61L15/20A61L15/26A61L15/28A61L15/44A61L15/32A61L15/42
CPCA61L15/18A61L15/20A61L15/26A61L15/28A61L15/32A61L15/42A61L15/44A61L15/46A61L26/00A61L26/0004A61L26/0019A61L26/0023A61L26/0061A61L26/0066A61L2300/10A61L2300/45A61L2300/404A61L2300/414A61L2300/232A61L2300/252C08L83/04C08L5/08C08L5/04C08L89/00Y02A50/30
Inventor 崔广州
Owner 郑州和济生物科技股份有限公司
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