Preparation method and use method of hydrogel local anesthesia patch

Abstract

The invention discloses a preparation method of a hydrogel local anesthesia patch. The preparation method comprises the following steps of 1, nanogold dispersion liquid preparation; 2, PDA-PAM hydrogel preparation; 3, PDA-PAM-AuNps hydrogel preparation; 4, hydrogel local anesthesia patch finished product preparation. The hydrogel local anesthesia patch can generate heat under the excitation of near infrared light, and the penetration of local anesthesia medicine in the patch in tissues is promoted; meanwhile, the hydrogel local anesthesia patch also has the following technical advantages that1, a microneedle is used for puncturing the surface of a mucosa or the skin; the aching feeling is weak; 2, some problems and defects such as unprecise anesthesia region, swelling after injection andslow recovery caused by injection anesthesia can be avoided; 3, the process is simple and safe; the operation method is simple; the equipment requirements are low; the hydrogel local anesthesia patchis suitable for large-scale production and industrialization.

Description

technical field [0001] The invention relates to the field of anesthesia, in particular to a method for preparing a hydrogel local anesthesia patch and a method for using it. Background technique [0002] Local anesthesia is widely used in modern medicine. It refers to the use of local anesthetics to temporarily block the sensory conduction of nerve endings and fibers in a certain area of ​​the body, so that the pain in this area disappears. Taking oral treatment as an example, local anesthesia is commonly used in the treatment of endodontics, tooth extraction, minor maxillofacial surgery and pain treatment, and dental implants. [0003] Different local anesthesia methods are used clinically, such as topical anesthesia. The local anesthetic drug is made into a gel state and applied to the area that needs anesthesia. discomfort. There are also studies reporting a new method of injecting medicine without a needle, using a high-speed high-pressure injector to inject anesthetic...

AI Technical Summary

Problems solved by technology

In addition, the use of traditional syringes for local anesthesia can also bring some additional problems, such as possible fainting due to the patient's excessive nervousness and fear; overdose reactions; pain at the injection site; hematoma; infection and broken injection needles, etc.