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Cannabidiol hemorrhoid suppository for treating qi stagnation and blood stasis, and preparation method thereof

A technology for cannabidiol hemorrhoids, qi stagnation and blood stasis, which is applied in the directions of medical preparations containing active ingredients, suppository delivery, pharmaceutical formulations, etc. The effect of increasing the content of the drug and reducing the risk of drug abuse

Inactive Publication Date: 2019-06-21
WUHAN SHENGRUN BIOTECHNOLOGY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] But oral effect is slow

Method used

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  • Cannabidiol hemorrhoid suppository for treating qi stagnation and blood stasis, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] 1. Formula

[0035] Tianqi 80g, cannabidiol 80g, Sensinia 90g, Houttuynia cordata 80g, palm 100g, alum 60g, calamine 60g, peach kernel 10g, beeswax 500g, Tween 80 70g.

[0036] 2. Preparation method

[0037] step 1,

[0038] According to the formula, take the palm and crush it through a 40-mesh sieve, mix it evenly, add distilled water to make a 0.20g / ml suspension for later use; put the suspension in a hot pot, fry it until the surface is burnt black and the inside is burnt brown, spray Pour a little water, extinguish the spark, take it out, dry it, and use it as active ingredient A for later use.

[0039] In this embodiment, the tannin content determination method of the Pharmacopoeia of the People's Republic of China (2015 edition) is used to determine the percentage content of tannin before and after palm processing: tannin content=(T1-T2) / W×100%. In the formula: W is the sampling amount (dry product), T1 is the total phenol content in the sample, and T2 is the p...

Embodiment 2

[0048] 1. Formula

[0049] Tianqi 90g, cannabidiol 40g, Sensation grass 102.5g, Houttuynia cordata 105g, palm 160g, alum 100g, calamine 100g, peach kernel 20g, beeswax 500g, sodium stearate 80g.

[0050] 2. Preparation method

[0051] The preparation method is the same as in Example 1.

Embodiment 3

[0053] 1. Formula

[0054] Tian Qi 97.5g, Cannabidiol 70g, Sensation grass 60g, Houttuynia cordata 90g, Palm 140g, Alum 70g, Calamine 70g, Peach kernel 30g, Beeswax 600g, EDTA 60g.

[0055] 2. Preparation method

[0056] step 1,

[0057] According to the formula, take the palm and crush it through a 40-mesh sieve, mix it evenly, add distilled water to make a 0.20g / ml suspension for later use; put the suspension in a hot pot, fry it until the surface is burnt black and the inside is burnt brown, spray Pour a little water, extinguish the spark, take it out, dry it, and use it as active ingredient A for later use.

[0058] Step 2. According to the formula, the peach kernel, alum, and calamine are pulverized into fine powder and passed through a 40-mesh sieve, and used as the active ingredient B for subsequent use.

[0059] Step 3. Take Tianqi, Sensuocao and Houttuynia cordata according to the formula. After crushing, add ethanol solution with a volume fraction of 90% according...

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Abstract

The invention relates to a cannabidiol hemorrhoid suppository for treating qi stagnation and blood stasis, and a preparation method thereof. The hemorrhoid suppository comprises, by weight, 8-12 partsof pseudo-ginseng, 4-10 parts of cannabisdiol, 6-15 parts of mimosa pudica, 8-12 parts of houttuynia cordata, 10-20 parts of palms, 6-10 parts of alum, 6-10 parts of calamine and 1-3 parts of peach kernels. The hemorrhoid suppository has strict compatibility and prominent effects, and the herbs are combined to achieve the effects of removing stasis, relieving pain, eliminating inflammation, detoxifying the body, promoting qi and activating blood circulation; clinical practice shows that the suppository has a unique curative effect on qi stagnation and blood stasis type hemorrhoids. The cannabidiol in the formula of the hemorrhoid suppository further enhances the anti-inflammatory and analgesic effects of the hemorrhoid suppository, and the risk of drug abuse is effectively reduced. The preparation method of the hemorrhoid suppository combines the homogenization process with stabilizers to improve the stability of the preparation, and accordingly, the problem of instability of suppositories prepared by conventional methods is solved. Moreover, the extraction method for active ingredients in the palms is optimized, and the contents of tannin and calcium in extract are remarkably increased, so that the effect of the hemorrhoid suppository is improved.

Description

technical field [0001] The invention relates to the technical field of traditional Chinese medicine, in particular to a cannabidiol hemorrhoid suppository for treating qi stagnation and blood stasis and a preparation method thereof. Background technique [0002] Anorectal disease is a common clinical disease and frequently-occurring disease. According to the survey of more than 50,000 people in some areas of my country, the incidence rate reaches 59.1%, and the incidence rate of hemorrhoids accounts for 87.25% of anorectal diseases. Western medicine often adopts surgical treatment for hemorrhoids. Although the surgical method has been greatly improved, after all, surgery is a traumatic treatment, which is not easy for many people to accept. And scholars at home and abroad generally believe that the treatment of hemorrhoids should be based on the principle of relieving symptoms rather than eliminating hemorrhoids. [0003] TCM treatment of hemorrhoids emphasizes the principl...

Claims

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Application Information

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IPC IPC(8): A61K36/889A61K31/05A61K9/02A61P9/14A61K33/06A61K33/30
Inventor 郑俊武金秀妍郑成武卫路刘群黄浩洪磊聂晓芬
Owner WUHAN SHENGRUN BIOTECHNOLOGY CO LTD
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