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Skin-care freeze-dried powder containing pigskin collagen polypeptide and preparation of skin-care freeze-dried powder

A technology of collagen polypeptide and skin collagen, applied in skin care preparations, cosmetic preparations, dressing preparations, etc., can solve the problems of insufficient utilization and reflection of nutritional and economic value, waste of resources, environmental pollution, etc. Achieve the effect of improving biological utilization value, convenient operation, and no environmental pollution

Inactive Publication Date: 2019-08-23
SHANGHAI INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, for a long time, pigskin has not been fully utilized and reflected in its nutritional and economic value, except that pigskin as a by-product is partially used in the leather and food industries. This not only wastes resources, but also causes certain environmental pollution.

Method used

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  • Skin-care freeze-dried powder containing pigskin collagen polypeptide and preparation of skin-care freeze-dried powder
  • Skin-care freeze-dried powder containing pigskin collagen polypeptide and preparation of skin-care freeze-dried powder
  • Skin-care freeze-dried powder containing pigskin collagen polypeptide and preparation of skin-care freeze-dried powder

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] A preparation method of skin care freeze-dried powder containing pigskin collagen polypeptide, the specific steps are:

[0050] (1) Dry and crush the pigskin to 40 mesh, weigh 100g of pigskin powder, add the weighed pigskin powder into distilled water, cook for 1 hour while stirring, cool to room temperature, and filter to obtain the pigskin aqueous solution ; The quality of distilled water is 6 times of that of dried pigskin powder.

[0051] (2) Adjust the pH value of the pigskin aqueous solution to 5 with glacial acetic acid and 0.1mol / L NaOH solution, then add complex enzymes to enzymolyze the protein in the pigskin aqueous solution at 40°C for 1 hour, and then inactivate the enzyme treatment to obtain an enzymatic hydrolyzate; the compound enzyme includes papain and animal protease with a weight ratio of 1:1, and the animal protease is purchased from Guangbo Nanning Pangbo Biotechnology Co., Ltd., with enzyme activity ≥ 200 units / mg. The added amount of compound en...

Embodiment 2

[0061] A preparation method of skin care freeze-dried powder containing pigskin collagen polypeptide, the specific steps are:

[0062] (1) Dry and crush the pigskin to 40 mesh, weigh 100g of pigskin powder, add the weighed pigskin powder into distilled water, cook for 1 hour while stirring, cool to room temperature, and filter to obtain the pigskin aqueous solution ; The quality of distilled water is 6 times of that of dried pigskin powder.

[0063] (2) Adjust the pH value of the pigskin aqueous solution to 6 with glacial acetic acid and 0.1mol / L NaOH solution, then add complex enzymes to enzymolyze the protein in the pigskin aqueous solution at 40°C for 1 hour, and then inactivate the enzyme treatment to obtain an enzymatic hydrolyzate; the compound enzyme includes papain and animal protease with a weight ratio of 2:1, and the animal protease is purchased from Guangbo Nanning Pangbo Biotechnology Co., Ltd., with an enzyme activity ≥ 200 units / mg. The added amount of compound...

Embodiment 3

[0075] A preparation method of skin care freeze-dried powder containing pigskin collagen polypeptide, the specific steps are:

[0076] (1) Dry and crush the pigskin to 40 mesh, weigh 100g of pigskin powder, add the weighed pigskin powder into distilled water, cook for 1 hour while stirring, cool to room temperature, and filter to obtain the pigskin aqueous solution ; The quality of distilled water is 6 times of that of dried pigskin powder.

[0077] (2) Adjust the pH value of the pigskin aqueous solution to 7 with glacial acetic acid and 0.1mol / L NaOH solution, then add complex enzymes to enzymolyze the protein in the pigskin aqueous solution at 40°C for 1 hour, and then inactivate the enzyme treatment to obtain an enzymatic hydrolyzate; the compound enzyme includes papain and animal protease with a weight ratio of 3:1, and the animal protease is purchased from Guangbo Nanning Pangbo Biotechnology Co., Ltd., with an enzyme activity ≥ 200 units / mg. The added amount of compound...

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Abstract

The invention provides skin-care freeze-dried powder containing pigskin collagen polypeptide and preparation of the skin-care freeze-dried powder. The preparation method comprises the steps that pigskin is dried, crushed, added into water, boiled for 1-4 hours and cooled to room temperature to obtain a pigskin aqueous solution; then complex enzyme is added for enzymolysis of protein in the pigskinaqueous solution to obtain enzymatic hydrolysate; the enzymatic hydrolysate is subjected to decoloration to obtain the decolored enzymatic hydrolysate, and then the decolored enzymatic hydrolysate issequentially subjected to filtering through a membrane and concentration to obtain the pigskin collagen polypeptide; the pigskin collagen polypeptide, an epidermal growth factor and a freeze-drying protective agent are dissolved into water, and the obtained solution is freeze-dried to obtain the skin-care freeze-dried powder containing the pigskin collagen polypeptide. The freeze-drying technology is adopted to realize the long-term effective quality guarantee of the skin-care freeze-dried powder without adding preservatives, the irritation of the skin-care freeze-dried powder is reduced, andthe application range is enlarged.

Description

technical field [0001] The invention relates to the technical field of polypeptide skin care freeze-dried powder, in particular to a skin care freeze-dried powder containing pigskin collagen polypeptide and a preparation process thereof. Background technique [0002] The rapid development and wide application of modern technology has brought brand-new development and opportunities to the beauty cosmetics industry. Skin care products have developed from chemical beauty and plant beauty to biological beauty and gene beauty. Active biological peptides have the advantages of being safe and stable, easily soluble in water, and easy to absorb. At the same time, they have various physiological functions such as anti-oxidation, anti-aging, and scavenging free radicals. They can not only promote the proliferation of skin cells, but also provide nutrition for the skin and delay Skin aging can promote skin wound repair, so it is widely used in skin care cosmetics and other fields. [...

Claims

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Application Information

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IPC IPC(8): A61K8/02A61K8/65A61K8/64A61K8/34A61K8/44A61Q19/08A61Q19/00
CPCA61K8/022A61K8/345A61K8/44A61K8/64A61K8/65A61Q19/00A61Q19/08
Inventor 徐小威李桂华赵玉莲刘英
Owner SHANGHAI INST OF TECH
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