Amphiphilic temperature-sensitive block polymer base on phenylboronic acid and preparation method and application thereof

A temperature-sensitive block and amphiphilic technology, applied in the field of fractional purification of natural products, can solve the problems of time-consuming procedures, limited large-scale application, complex operation, etc., and achieve good compatibility and fast association/desorption kinetics Effect
CN110669186AActive Publication Date: 2020-01-10JIANGSU UNIV
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Patent Information

Authority / Receiving Office
CN ยท China
Patent Type
Applications(China)
Current Assignee / Owner
JIANGSU UNIV
Publication Date
2020-01-10

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Abstract

The invention belongs to the field of classification and purification of natural products, and particularly relates to an amphiphilic temperature-sensitive block polymer based on phenylboronic acid and a preparation method and application thereof. Accord to that invention, a temperature-sensitive block and a phenylboronic acid block are polymerized by use a chain transfer technology to obtain theamphiphilic temperature-sensitive block polymer based on phenylboronic acid, and the obtained block polymer has the functions of ortho-dihydroxy identifying and temperature-sensitivity; according to the invention, the amphiphilic temperature-sensitive block polymer is combined with polysaccharides containing ortho-dihydroxy, polysaccharides with different molecular weights are aggregated and precipitated by adjusting different temperatures, and classification and purification of the polysaccharides are realized. Compared with the current common method, the temperature-controlled precipitationmethod for different fractions of polysaccharide is more green and environment-friendly, and the structure and activity of each polysaccharide sample are not damaged.
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Description

technical field

[0001] The invention belongs to the technical field of fractional purification of natural products, and in particular relates to a phenylboronic acid-based amphiphilic temperature-sensitive block polymer and its preparation method and application. Background technique

[0002] Polysaccharides have been widely studied in the food and pharmaceutical industries due to their low toxicity and high specificity in activating the immune system. Studies have shown that polysaccharides have many biological activities, such as anti-oxidation, anti-tumor, anti-virus, anti-diabetes, anti-inflammatory, and immune regulation and liver protection. The biological activity of polysaccharides is usually closely related to its chemical and physical properties, including glycosidic bonds, functional groups, monosaccharide composition and molecular weight (Mw) and other characteristics, especially the molecular weight of polysaccharides has a significant impact on the activity of ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
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