The invention discloses a zero-forcing
frequency domain equalization-based molecular
code division multiple access system detection method and device. The method comprises the following steps of: constructing a molecular
code division multiple access system; each nano emitter performs spectrum spreading on data by using a spectrum spreading sequence, and represents a molecular concentration
signal of bit information by releasing A-type and B-type molecules; sampling the received molecular concentration
signal at the
fusion center, and determining a concentration difference observation value of A type molecules and B type molecules; on the basis of the observation value, organizing data in a block transmission mode and inserting a
cyclic prefix to eliminate inter-block interference, and forming a
time domain observation vector; converting the
time domain signal into a
frequency domain signal; suppressing inter-symbol, inter-
chip and multi-access interference by applying a zero-forcing
frequency domain equalization algorithm; performing inverse
fast Fourier transform on the equalized signal, converting the equalized signal back to a
time domain, and obtaining a judgment variable through de-spreading operation; and comparing the judgment variable with a zero threshold, if the judgment variable is greater than 0, judging as 1, otherwise, judging as-1, and outputting a decoding bit sequence.