Content determination method for spermatogenic tablets
A determination method and content technology, which is applied in the field of content determination of Shengjing Tablets, can solve the problems of inability to monitor the drug content of the drug king and minister, single quality standard content detection, etc., and achieve the effects of small error, good reproducibility, and cost saving
Active Publication Date: 2020-02-07
XIAN CHIHO PHARMA
View PDF4 Cites 3 Cited by
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Problems solved by technology
[0005] The purpose of the invention is to overcome the deficiencies in the prior art, to provide a method for determining the content of betaine in Shengjing Tablets, to effectively control the quality of the medicine, and to make the quality of the medicine reach a stable, controllable, efficient and safe standard; to overcome Solve the problem that the content detection of the quality standard in the prior art is too single, only the content detection is carried out on drynaria rhizome directly powdered into medicine, and the content of the king and minister in the medicine cannot be monitored.
Method used
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View moreImage
Smart Image Click on the blue labels to locate them in the text.
Smart ImageViewing Examples
Examples
Experimental program
Comparison scheme
Effect test
Embodiment 1
[0034] A method for determining the content of Shengjing Tablets, which uses the Shengjing Tablets produced by Xi'an Qianhe Pharmaceutical Co., Ltd. to test, and uses liquid chromatography to measure the content of betaine in Lycium barbarum, comprising the following steps:
[0035] Step 1: Liquid Chromatography Conditions
[0036] Use propylamide bonded silica gel and C18 silica gel column as filler; use volume ratio of 20-30:80-70 acetonitrile-water, 20-30:80-70 acetonitrile-0.2% acetic acid solution, 20-30: 0.2% phosphoric acid-acetonitrile at 80-70 is the mobile phase; UV detector, detection wavelength 120-260nm; flow rate 0.6ml / min-1.2ml / min; column temperature 30°C; Below 3000.
[0037] (1) Determine the wavelength and select the optimal wavelength.
[0038] Weigh an appropriate amount of betaine reference substance, dissolve it in methanol, and perform a spectral scan in the range of 120-260nm. As a result, betaine has a maximum absorption at a wavelength of 192nm, so...
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More PUM
| Property | Measurement | Unit |
|---|---|---|
| Wavelength | aaaaa | aaaaa |
Login to View More
Abstract
The invention relates to a content determination method for spermatogenic tablets. According to the method, a liquid chromatogram is adopted to determine the content of betaine which is an effective constituent in fructus lycii in a spermatogenic tablet preparation. Through the method, detection of the betaine content is added on the basis that only psoralen and isopsoralen are detected accordingto an original quality standard. Compared with the prior art that an HPLC method is adopted to determine the betaine content in a fructus lycii medicinal material, an ion exchange resin method is notadopted to treat a test solution, the requirement on equipment is low, the method is simple, reproducibility is good, an error is small, and cost is saved.
Description
technical field [0001] The invention belongs to the technical field of detection of traditional Chinese medicine components, and in particular relates to a content determination method of spermatogenic tablets. Background technique [0002] Sperm tablets are composed of wolfberry fruit, sand garden fruit, epimedium, Polygonum multiflorum, mulberry, drynaria, curculigo, golden cherry, raspberry, sage vine, verbena, ginkgo leaf, dodder, cordyceps, sealwort, pilose antler , Eucommia, ginseng, and psoraleae nineteen medicines processed into tablets (film-coated), functions and indications: nourishing kidney and essence, nourishing yin and strengthening yang. It is used for symptoms such as weakness of the waist and knees, dizziness, tinnitus, mental fatigue and fatigue caused by deficiency of kidney yang, men with infertility, oligospermia, weak semen, and semen not liquefied. The drug is formulated from traditional classic prescriptions. All the drugs in the prescription have ...
Claims
the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More Application Information
Patent Timeline
Login to View More IPC IPC(8): G01N30/02G01N30/06G01N30/14
CPCG01N30/02G01N30/06G01N30/14G01N2030/047G01N2030/146
Inventor 李晓娣张琼吕慧锋胡小虎谭祥和
Owner XIAN CHIHO PHARMA