Veterinary tilmicosin premix powder drug

A technology of tilmicosin and premix, which is applied in powder delivery, antibacterial drugs, pharmaceutical formulations, etc., can solve the problems of toxic and side effects, inability to cure diseases, etc., and achieve strong tissue penetration and preparation Stable, long-lasting effect

CN110917203AInactive Publication Date: 2020-03-27临沂文一诺知识产权运营有限公司
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Patent Information

Authority / Receiving Office
CN · China
Patent Type
Applications(China)
Current Assignee / Owner
Publication Date
2020-03-27
Estimated Expiration
Not applicable · inactive patent

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Abstract

The invention discloses a veterinary tilmicosin premix powder drug, belonging to the technical field of veterinary drugs. The veterinary tilmicosin premix powder drug provided by the invention is composed of tilmicosin, trimethoprim lactate and anhydrous glucose. According to the invention, through combination of the tilmicosin and a synergist, the whole powder is reinforced in treatment effect; and the veterinary tilmicosin premix powder drug can be used for treating infectious pleuropneumonia, plague, enzootic pneumonia and the like of pigs or cattle. The veterinary tilmicosin premix powderdrug provided by the invention is rapid to be absorbed after being taken orally, has the characteristics of strong tissue penetrating power, high lung concentration and long effective blood concentration maintaining time, has stable preparation, and is simple in preparation process and convenient to use.
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Description

technical field

[0001] The invention belongs to the technical field of veterinary medicine, in particular to a tilmicosin premix powder medicine for veterinary use. Background technique

[0002] Tilmicosin is a semi-synthetic macrolide antibacterial drug for animals. Its antibacterial effect is similar to that of tylosin. The sensitive Gram-positive bacteria include Staphylococcus aureus (including penicillin-resistant Staphylococcus aureus), pneumococcus , Streptococcus, Bacillus anthracis, Erysipelas suis, Listeria, Clostridium putrefaction, Clostridium emphysema etc. Sensitive Gram-negative bacteria include Haemophilus, Neisseria meningitidis, Pasteurella, etc., and are also effective against mycoplasma. The activity against Actinobacillus pleuropneumoniae, Pasteurella and Mycoplasma is stronger than Tylosin. It is mainly used for the prevention and treatment of livestock pneumonia, caused by Actinobacillus pleuropneumoniae, Pasteurella, Mycoplasma and other infections,...

Examples

Embodiment 1

[0017] Prescription: every 100g of medicine contains 18g of tilmicosin, 1.5g of trimethoprim lactate, and the balance is anhydrous glucose.

[0018] Preparation:

[0019] (1) Grind and sieve the tilmicosin, trimethoprim lactate, and anhydrous glucose in the prescription amount, respectively, and set aside;

[0020] (2) Weigh the two raw materials of tilmicosin and trimethoprim lactate, add the same amount of anhydrous glucose as the sum of the two raw materials, and pre-mix for 15 minutes according to the dispersion method;

[0021] (3) Then add the remaining anhydrous glucose and mix thoroughly for 40 minutes, and mix well.

Embodiment 2

[0023] Prescription: every 100g of medicine contains 18g of tilmicosin, 2.5g of trimethoprim lactate, and the balance is anhydrous glucose.

[0024] The preparation method is the same as in Example 1.

Embodiment 3

[0026] Prescription: every 100g of medicine contains 19g of tilmicosin, 1.8g of trimethoprim lactate, and the balance is anhydrous glucose.

[0027] The preparation method is the same as in Example 1.