Entoiodine skin mucosa disinfectant as well as preparation method and application thereof
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The technology of a disinfectant and Aner Iodine is applied in skin diseases, pharmaceutical formulations, active ingredients of iodine compounds, etc. It can solve the problems of unsatisfactory use effect and low solubility, and achieve the effect of small irritation, low toxicity and simple formula
Pending Publication Date: 2020-04-21
JILIN YUNFEI PHARMA CO LTD
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Problems solved by technology
[0003] In summary, the existing problems in the prior art are: there are many types of skin and mucous membrane disinfectants commonly used, but each type of commonly used disinfectant has its own disadvantages, and the use effect is not ideal.
[0006] Iodine is highly soluble in ethanol but very little in water
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preparation example Construction
[0029] Such as figure 1 As shown, the preparation method of Aneriodine skin and mucous membrane disinfectant provided by the embodiments of the present invention may further comprise the steps:
[0030] S101: prepare raw materials by weight: iodine 0.23% of purity 99%, ethanol 60% of purity 95%, chlorhexidine acetate 0.5% of purity 99%, potassium iodide 0.17% of purity 99%, potassium iodate of purity 99% 0.15%, 0.05% of peppermint oil with a purity of 50%, 3.0% of glycerin with a purity of 99%, and the balance is composed of purified deionized water;
[0031] S102: dissolving potassium iodide, potassium iodate, iodine, chlorhexidine acetate, peppermint oil and glycerin in an ethanol solution, and stirring to obtain a homogeneous solution;
[0032] S103: adding purified ionized water to the full amount, constant volume and aging;
[0033] S104: inspecting the obtained intermediate product;
[0034] S105: If qualified, use plastic bottles and heads of disinfectant for potting...
Embodiment
[0038] 1000kg prescription composition:
[0039] raw material name purity Amount added (Kg) Total (%) iodine 99% 2.3 0.23 ethanol 95% 600 60 Chlorhexidine acetate 99% 5 0.5 potassium iodide 99% 1.7 0.17 potassium iodate 99% 1.5 0.15 peppermint 50% 0.5 0.05 glycerin 99% 30 3.0 Deionized water 100% 360.5 36.05
[0040] As we all know, the workload of hospitals to disinfect the skin and mucous membranes of patients is increasing day by day, and the demand for skin and mucous membrane disinfectant is increasing day by day, such as surgical dressing changes, blood collection and injection, etc. The liquid has the characteristics of rapid sterilization. Aner iodine disinfectant is generally used in clinical practice in hospitals. It is used for disinfection before general skin punctures such as muscle and intravenous injection. It is used for disinfection of special parts such as surgical sites, surgic...
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Abstract
The invention belongs to the technical field of skin mucosa disinfectants, and particularly relates to an entoiodine skin mucosa disinfectant and a preparation method and application thereof. The entoiodine skin mucosa disinfectant comprises iodine, ethanol, chlorhexidine acetate, potassium iodide and the balance of purified deionized water. The entoiodine skin mucosa disinfectant comprises the following components in parts by weight: 0.23% of iodine with the purity of 99%; 60.0% of ethanol with purity of 95%; 0.5% of chlorhexidine acetate with the purity of 99%; 0.17% of potassium iodide withthe purity of 99%, 0.15% of potassium iodate with the purity of 99%, 0.05% of peppermint oil with the purity of 50%, 3.0% of glycerin with the purity of 99% and the balance purified deionized water.The entoiodine skin mucosa disinfectant is an environment-friendly sterilization disinfectant, and has the characteristics of wide sterilization spectrum and high efficiency; the entoiodine skin mucosa disinfectant can be used at normal temperature, and is long in antibacterial time, low in toxicity, safe and effective; no corrosion is caused on various materials; the effects of disinfection, sterilization, skin moistening and water retention are achieved.
Description
technical field [0001] The invention belongs to the technical field of skin and mucous membrane disinfectant, and in particular relates to aneriodine skin and mucous membrane disinfectant and its preparation method and application. Background technique [0002] Skin and mucous membrane disinfection is a common disinfection work in health care institutions. At present, there are many kinds of disinfectants, which mainly include oxidation, aldehydes, alcohols, heavy metal salts, halogens, and surfactants according to the mechanism of action. The more commonly used ones are aldehydes such as formaldehyde, glutaraldehyde, and surfactants. benzalkonium bromide (brogeramine). However, the commonly used disinfectants mentioned above have their own disadvantages. Oxidizing disinfectants such as peroxide disinfectants are chemically unstable, and high concentrations can irritate the skin and cause damage to mucous membranes; aldehyde disinfectants such as formaldehyde are A Carcino...
Claims
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Application Information
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