Production method of water-soluble functional red yeast rice powder

A red yeast rice powder and water-soluble technology, which is applied in the field of preparation of water-soluble functional red yeast rice powder, can solve the problems of cumbersome extraction steps, unsuitable extraction process for scale-up production, and high requirements for equipment and environment, and achieves cumbersome extraction steps and no precipitation. Stability and good water solubility

Active Publication Date: 2020-05-12
安诺康(福建)生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The extraction of the functional substance lovastatin in red yeast rice powder generally adopts alcohol extraction or acid-base adjustment process. The extraction process requires high equipment and environment and is easy ...

Method used

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  • Production method of water-soluble functional red yeast rice powder
  • Production method of water-soluble functional red yeast rice powder
  • Production method of water-soluble functional red yeast rice powder

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Experimental program
Comparison scheme
Effect test

Embodiment 1

[0033] A preparation method of water-soluble functional red yeast rice powder, specifically comprising:

[0034] The first stage of solid-state fermentation includes the following specific steps:

[0035] (1) Strain activation: the pure strain of Monascus was inserted into the plate medium, and cultured at 30°C for 5 days to activate the strain;

[0036] (2) Preparation of primary seed liquid: Add 20 mL of sterile saline to the plate culture medium of activated strains, rub the mycelium back and forth with an inoculation loop to wash the spores and mycelium to make a plate seed liquid, press 2% The inoculation amount is inoculated into the seed medium, 30°C, 100rpm, and cultivated for 48 hours;

[0037](3) Preparation of the secondary seed solution: inoculate the primary seed solution into the seed medium (250mL / 1000mL) at an inoculum volume of 10% under sterile conditions, and cultivate for 24 hours at 30°C and 100rpm;

[0038] (4) Solid-state fermentation: Under sterile co...

Embodiment 2

[0052] A preparation method of water-soluble functional red yeast rice powder, specifically comprising:

[0053] The first stage of solid-state fermentation includes the following specific steps:

[0054] (1) Strain activation: the pure strain of Monascus was inoculated into the plate medium, and cultured at 30°C for 10 days to activate the strain;

[0055] (2) Preparation of primary seed liquid: Add 20 mL of sterile saline to the plate culture medium of activated strains, rub the mycelium back and forth with an inoculation loop to wash the spores and mycelium to make a plate seed liquid, press 2% The inoculation amount is inoculated into the seed medium, 30°C, 100rpm, and cultivated for 48 hours;

[0056] (3) Preparation of the secondary seed solution: inoculate the primary seed solution into the seed medium (250mL / 1000mL) at an inoculum volume of 10% under sterile conditions, and cultivate for 24 hours at 30°C and 100rpm;

[0057] (4) Solid-state fermentation: Under steril...

Embodiment 3

[0069] A preparation method of water-soluble functional red yeast rice powder, specifically comprising:

[0070] The first stage of solid-state fermentation includes the following specific steps:

[0071] (1) Strain activation: the pure strain of Monascus was inserted into the plate medium, and cultured at 30°C for 8 days to activate the strain;

[0072] (2) Preparation of primary seed liquid: Add 20 mL of sterile saline to the plate culture medium of activated strains, rub the mycelium back and forth with an inoculation loop to wash the spores and mycelium to make a plate seed liquid, press 2% The inoculation amount is inoculated into the seed medium, 30°C, 100rpm, and cultivated for 48 hours;

[0073] (3) Preparation of the secondary seed solution: inoculate the primary seed solution into the seed medium (250mL / 1000mL) at an inoculum volume of 10% under sterile conditions, and cultivate for 24 hours at 30°C and 100rpm;

[0074] (4) Solid-state fermentation: under aseptic c...

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Abstract

The invention discloses a production method of water-soluble functional red yeast rice powder, and belongs to the technical field of microbial fermentation. According to the production method, with monascus which do not produce citrinin and highly produce lovastatin as starting fungi and edible fungus culture bags as fermentation containers, solid fermentation is conducted on grains, and then through water extraction, plate-frame pressure filtration, ultrafiltration, nanofiltration and freeze drying, the water-soluble functional red yeast rice powder containing the lovastatin is produced. Allthe lovastatin in the water-soluble functional red yeast rice powder is of an open-loop structure, a product has good water solubility, and an aqueous solution produced from the water-soluble functional red yeast rice powder product can remain clear and transparent at a room temperature, does not have sediment and is good in stability.

Description

technical field [0001] The invention belongs to the technical field of microbial fermentation, and in particular relates to a preparation method of water-soluble functional red yeast rice powder. Background technique [0002] In addition to the synonym Danqu, red yeast rice is also known as red yeast rice, red rice, and Fuqu. It is of great significance in the development and utilization of microbiology in my country and the world. Functional red yeast rice refers to the red yeast rice (powder) containing the functional ingredient lovastatin produced by the fermentation of Monascus bacterium, which has the effect of lowering blood lipids; among them, lovastatin is a blood lipid lowering drug, which has two chemical structures, namely open ring structure and closed loop structure. The open-ring structure has good water solubility and is easy to be absorbed and utilized by the human body to exert its effect, while the closed-loop structure has poor water solubility. After tak...

Claims

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Application Information

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IPC IPC(8): C12P1/02C12N1/14C12R1/645
CPCC12P1/02C12N1/14C12R2001/645C12N1/145
Inventor 高益槐戴金玉吴学明李小娟黄图成
Owner 安诺康(福建)生物科技有限公司
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