Preparation method of sleeping dispersible tablets
A technology of dispersible tablets and extractors, which is applied in the direction of non-active ingredient medical preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve the problem of inability to remove hydrophilic ingredients, affect the next tableting process Particles are easy to absorb moisture and other problems, to achieve the effect of shortening the disintegration time limit, improving bioavailability, and high bioavailability
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[0040] Example 1
[0041] A preparation method of Shumian dispersible tablet, comprising the following steps:
[0042] (1) Take 600g of jujube seed, 350g of Bupleurum, 350g of Radix Paeoniae Alba, 450g of Albizia Julibrissin, 450g of Albizia Julibrissin, 250g of Silkworm, add 10 times the amount of water, heat and boil the medicinal materials, keep boiling for 1 hour, decocted Cook twice, combine the decoction liquid, let the liquid cool down to room temperature and then add ethanol to make the alcohol content 75%, stir while adding, transfer to the cold storage after the addition, and let stand at 5-10 ° C for 24 hours, filter the supernatant with suction.
[0043] (2) Take 25 g of the medicinal material rushes and place it in an extractor, add 8 times the amount of ethanol, extract twice by reflux, and combine the extracts.
[0044](3) The above-mentioned supernatant and extract were combined, concentrated under reduced pressure to a clear paste with a relative density of ...
Example Embodiment
[0048] Example 2
[0049] A preparation method of Shumian dispersible tablet, comprising the following steps:
[0050] (1) Take 650g of Suanzao Ren, 380g of Bupleurum, 380g of Paeonia lactiflora, 480g of Albizia Julibrissin, 480g of Albizia Julibrissin, and 300g of Silkworm, add 10 times the amount of water, heat and boil the medicinal materials, keep boiling for 1 hour, decocted Cook twice, combine the decoction liquid, let the liquid cool down to room temperature and then add ethanol to make the alcohol content 75%, stir while adding, transfer to the cold storage after the addition, and let stand at 5-10 ° C for 24 hours, filter the supernatant with suction.
[0051] (2) Take 30 g of the medicinal material rushes and place it in an extractor, add 8 times the amount of ethanol, extract twice by reflux, and combine the extracts.
[0052] (3) The above-mentioned supernatant and extract were combined, concentrated under reduced pressure to a clear paste with a relative density...
Example Embodiment
[0056] Example 3
[0057] A preparation method of Shumian dispersible tablet, comprising the following steps:
[0058] (1) Take 700g of jujube seed, 400g of Bupleurum, 400g of Radix Paeoniae Alba, 500g of Albizia Julibrissin, 500g of Albizia Julibrissin, 350g of Silkworm, add 10 times the amount of water, heat and boil the medicinal materials, keep boiling for 1 hour, decocted Cook twice, combine the decoction liquid, let the liquid cool down to room temperature and then add ethanol to make the alcohol content 75%, stir while adding, transfer to the cold storage after the addition, and let stand at 5-10 ° C for 24 hours, filter the supernatant with suction.
[0059] (2) Take 35 g of the medicinal material rushes and place it in an extractor, add 8 times the amount of ethanol, extract twice by reflux, and combine the extracts.
[0060] (3) The above-mentioned supernatant and extract were combined, concentrated under reduced pressure to a clear paste with a relative density of...
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