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Compound abamectin transdermal solution for pets, and preparation method and use method thereof

A compound abamectin and transdermal technology, which is applied in the field of compound abamectin transdermal solution for pets, can solve the problem of slow onset and can not satisfy the treatment of parasitic diseases and secondary infections of bacteria and fungal skin diseases at the same time Demand and other issues, to achieve the effect of fast onset, low cost, and broad insect resistance spectrum

Inactive Publication Date: 2020-09-08
JIANGSU NANJING AGRI UNIV ANIMAL PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] The technical problem to be solved in the present invention is to provide a compound avermectin transdermal solution for pets and its preparation and use method, to solve the existing single abamectin transdermal agent, which still has limitations in clinical use, Such as limited anti-insect spectrum, slow onset of action, unable to meet the treatment needs of parasitic diseases and secondary infection bacterial and fungal skin diseases at the same time

Method used

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  • Compound abamectin transdermal solution for pets, and preparation method and use method thereof
  • Compound abamectin transdermal solution for pets, and preparation method and use method thereof
  • Compound abamectin transdermal solution for pets, and preparation method and use method thereof

Examples

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Effect test

Embodiment 1

[0026] A kind of compound recipe Abamectin transdermal solution, its composition and weight percent are:

[0027]

[0028] The preparation volume is 100ml, and it is prepared through the following steps:

[0029] (1) First weigh 2 / 3 of the ethanol of the formula, and preheat to 40-50°C;

[0030] (2) Add the propylene glycol and azone of formula quantity successively, stir to make dissolving completely;

[0031] (3) Accurately weigh the Abamectin B1, pyrethrins, hibiscus bark extract, neem bark extract and menthol of formula quantity respectively, add in the above-mentioned solution successively, stir, make each component dissolve completely;

[0032] (4) Dilute to volume with the remaining amount of ethanol.

Embodiment 2

[0034] A kind of compound recipe Abamectin transdermal solution, its composition and weight percent are:

[0035]

[0036] The preparation volume is 100ml, and it is prepared through the following steps:

[0037] (1) First weigh 2 / 3 of the ethanol of the formula, and preheat to 40-50°C;

[0038] (2) Add the propylene glycol and azone of formula quantity successively, stir to make dissolving completely;

[0039] (3) Accurately weigh the Abamectin B1, pyrethrins, hibiscus bark extract, neem bark extract and menthol of formula quantity respectively, add in the above-mentioned solution successively, stir, make each component dissolve completely;

[0040] (4) Dilute to volume with the remaining amount of ethanol.

Embodiment 3

[0042] A kind of compound recipe Abamectin transdermal solution, its composition and weight percent are:

[0043]

[0044] The preparation volume is 100ml, and it is prepared through the following steps:

[0045] (1) First weigh 2 / 3 of the ethanol of the formula, and preheat to 40-50°C;

[0046] (2) Add the propylene glycol and azone of formula quantity successively, stir to make dissolving completely;

[0047] (3) Accurately weigh the Abamectin B1, pyrethrins, hibiscus bark extract, neem bark extract and menthol of formula quantity respectively, add in the above-mentioned solution successively, stir, make each component dissolve completely;

[0048] (4) Dilute to volume with the remaining amount of ethanol.

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Abstract

The invention discloses a compound abamectin transdermal solution for pets, and a preparation method and use method thereof, and relates to the field of veterinary preparations. The compound abamectintransdermal solution for pets comprises the following raw materials in parts by weight: 0.5% of abamectin B1, 10%-25% of pyrethrin, 1%-5% of a cortex pseudolaricis extract, 0.5%-5% of a cortex meliaeextract, 0.5%-3% of menthol, 2%-8% of azone, 3%-15% of propylene glycol and the balance of an organic solvent. The compound abamectin transdermal solution can be used for treating parasitic diseases,secondary infection bacteria, fungal skin diseases and the like of pets, has a remarkable treatment effect on the secondary infection bacteria and fungal skin diseases of pets due to parasitic diseases, has the effects of relieving pain, diminishing swelling, diminishing inflammation and relieving itching, and can remarkably improve symptoms of skin diseases of pets. Compared with a single abamectin transdermal solution, the compound abamectin transdermal solution disclosed by the invention is wider in insect-resistant spectrum and stronger in insect-resistant activity.

Description

technical field [0001] The invention relates to the field of veterinary drug preparations, in particular to a compound abamectin transdermal solution for pets and its preparation and use method. The external transdermal solution can be used to treat pets caused by ticks, mites, lice, fleas and other body surfaces. Parasitic diseases caused by parasites and internal nematode infections. Background technique [0002] Parasitic diseases caused by external parasites (ticks, mites, fleas and lice, etc.) and internal nematodes are one of the common diseases of pets. All kinds of internal and external parasites will take the nutrition of the animal body to varying degrees, damage the tissue cells of the animal, secrete toxins, affect the growth and development of pets, and spread a variety of diseases. These are all seriously endangering the health of pets, even threatening the health of humans. There are many types of parasites, and it is difficult to effectively prevent and con...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K47/10A61K47/22A61K36/58A61P31/04A61P31/10A61P33/14A61K31/045A61K31/365A61K31/7048
CPCA61K9/0004A61K9/08A61K47/22A61K47/10A61K31/7048A61K31/365A61K36/15A61K36/58A61K31/045A61P31/04A61P31/10A61P33/14A61K2300/00
Inventor 彭麟季辉万荣峰刘丽
Owner JIANGSU NANJING AGRI UNIV ANIMAL PHARM CO LTD
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