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Method for extracting 1,8-cineole from tea tree oil

A technology of eucalyptol and tea tree oil, which is applied in the field of extraction 1, can solve the problems of high energy consumption and low purity of 1,8-cineole products, and achieve the effects of good selectivity, mild conditions and easy processing

Active Publication Date: 2020-09-22
成都市明典世家生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] The purpose of the present invention is to provide a method for extracting 1,8-cineole from tea tree oil to solve the problems of high energy consumption and low purity of 1,8-cineole in the existing method for removing 1,8-cineole from tea tree oil. , 8-cineole method

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0050] Get tea tree crude oil (terpinene-4-ol 40%, γ-terpinene 40% and 1,8-cineole 20%) 100ml and equal volume of 1-butyl-3-methylimidazole lactic acid Salt ionic liquids were mixed, and liquid-liquid stirring extraction was carried out at 30°C for 120min. Static layering, separation of the upper tea tree essential oil phase (terpinen-4-ol 42.2%, γ-terpinene 43.2% and 1,8-cineole 14.6%) and the lower phase containing ionic liquid and other components (Terpinene-4-ol 24.6%, γ-Terpinene 17.6% and 1,8-Cineole 57.8%). Get the upper tea tree essential oil phase and extract it twice with 1-butyl-3-methylimidazolium ionic liquid to obtain high-quality tea tree essential oil (45.2% of terpinene-4-alcohol, 49.6% of γ-terpinene and 1,8 - Eucalyptol 5.2%).

[0051] The extracted ionic liquid phase was mixed with water in an equal volume ratio, stirred and extracted at 25° C. for 30 min, and then the upper and lower phases were separated. The upper oil phase is the crude product of 1,8...

Embodiment 2

[0054] Take tea tree crude oil (terpinene-4-ol 40%, γ-terpinene 40% and 1,8-cineole 20%) 100ml and 200ml 1-butyl-3-methylimidazole lactate The ionic liquids were mixed, and the liquid-liquid stirring extraction was carried out at 30° C. for 120 min. Layering, after the phase interface is clear, separate, the upper tea tree oil phase (43.1% terpinene-4-ol, 45.0% gamma-terpinene and 11.8% 1,8-cineole) with ionic liquid and other Lower phase of components (terpinen-4-ol 27.9%, gamma-terpinene 20.4% and 1,8-cineole 51.8%). Get the upper tea tree oil phase and extract it again with 1-butyl-3-methylimidazole to obtain high-quality tea tree essential oil (44.6% of terpinene-4-ol, 48.7% of γ-terpinene and 1,8-eucalyptus leaf element 6.7%).

[0055] The extracted ionic liquid phase was mixed with water in an equal volume ratio, stirred and extracted at 25° C. for 30 min, and then the upper and lower phases were separated. The upper oil phase is the crude product of 1,8-cineole (the ...

Embodiment 3

[0058] Take tea tree crude oil (terpinene-4-ol 40%, γ-terpinene 40% and 1,8-cineole 20%) 100ml and 500ml 1-butyl-3-methylimidazole lactate The ionic liquids were mixed, and the liquid-liquid stirring extraction was carried out at 30° C. for 120 min. Layering, after the phase interface is clear, separate, the upper tea tree oil phase (43.8% terpinene-4-ol, 48.0% gamma-terpinene and 8.1% 1,8-cineole) with ionic liquid and other Lower phase of components (terpinen-4-ol 33.1%, gamma-terpinene 25.4% and 1,8-cineole 41.6%). Get the upper tea tree oil phase and extract it again with 1-butyl-3-methylimidazole to obtain high-quality tea tree essential oil (44.0% terpinene-4-ol, 52.9% gamma-terpinene and 1,8-eucalyptus leaf element 3.0%).

[0059] The extracted ionic liquid phase was mixed with water in an equal volume ratio, stirred and extracted at 25° C. for 60 min, and then the upper and lower phases were separated. The upper oil phase is the crude 1,8-cineole product (1,8-cineol...

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Abstract

The invention discloses a method for extracting 1,8-cineole from tea tree oil, which comprises the following steps: by using 1-alkyl-3-methylimidazolium lactate or choline dication malonate as an ionic liquid phase, mixing the ionic liquid phase with an oil phase, and performing extraction at normal pressure in a proper temperature range; after the phase equilibrium is reached, standing for layering, selectively extracting the 1,8-cineole from the oil phase to the ionic liquid phase, then separating an upper tea tree essential oil phase from the lower ionic liquid phase containing other components, collecting the ionic liquid phase after extraction, mixing the ionic liquid phase with water, and carrying out back extraction. After phase equilibrium is achieved, standing is conducted for layering, the main component of an upper-layer oil phase is 1,8-cineole, a lower-layer water phase is an ionic liquid aqueous solution, and after flash evaporation water removal, the ionic liquid can berecycled. According to the method, the extracting agent which is difficult to volatilize and easy to recycle is adopted, the selectivity is good, the condition is mild, the operation is simple, and more energy is saved compared with a traditional method for removing the 1,8-cineole.

Description

technical field [0001] The invention relates to the technical field of separation of natural active ingredients, in particular to a method for extracting 1,8-cineole from tea tree oil. Background technique [0002] Tea tree oil is native to Australia. It has good broad-spectrum bactericidal and antibacterial effects and the effect of promoting wound healing. It is an excellent natural antibacterial agent that can replace antibiotics. At the same time, tea tree oil also has good antioxidant effect and excellent skin penetration function, and is an excellent natural skin care oil. Tea tree essential oil is listed as one of the "ten most versatile and useful essential oils". More than 100 compounds have been identified in tea tree oil, and the representative components are terpinene-4-ol, α-terpinene, 1,8-cineole, etc. Among them, 1,8-cineole can cooperate with terpinen-4-ol in antibacterial and insecticidal at an appropriate concentration, and at the same time, a certain con...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C07D493/08C11B9/02B01D11/04
CPCC07D493/08C11B9/022B01D11/0492
Inventor 宋航李福林王小东张晶姚舜
Owner 成都市明典世家生物科技有限公司
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