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Traditional Chinese medicine composition for preventing and treating dengue virus and preparation method thereof

A technology of dengue fever virus and composition, which is applied in the field of medicine, can solve the problems of short drug effect time and poor curative effect, and achieve the effects of long drug effect time, good curative effect, and good control effect

Inactive Publication Date: 2020-10-09
广东卫康有害生物防制有限公司
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] The embodiment of the present invention provides a traditional Chinese medicine composition for preventing and treating dengue virus, aiming to solve the problem that the existing plant-derived medicines that can be used to prevent and treat dengue virus have short drug effect time and poor curative effect

Method used

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  • Traditional Chinese medicine composition for preventing and treating dengue virus and preparation method thereof
  • Traditional Chinese medicine composition for preventing and treating dengue virus and preparation method thereof
  • Traditional Chinese medicine composition for preventing and treating dengue virus and preparation method thereof

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preparation example Construction

[0024] The embodiment of the present invention also provides a preparation method of a traditional Chinese medicine composition for preventing and treating dengue virus, comprising the following steps:

[0025] In step 101, each component is weighed according to the formula of the above-mentioned traditional Chinese medicine composition for preventing and treating dengue virus, and set aside.

[0026] Step 102, adding 13-14 times the mass of Wulingzhi to Wulingzhi with ethanol with a mass concentration of 90-95%, heating to reflux for extraction, cooling to room temperature, filtering, collecting the ethanol extract, and concentrating to the original volume 10~12%, spray-dried to obtain Wulingzhi extract.

[0027] Step 103, mixing the Artemisia annua extract, perilla extract and the Wulingzhi extract to obtain the traditional Chinese medicine composition for preventing and treating dengue virus.

[0028] In step 102, it is preferable to add ethanol with a mass concentration o...

Embodiment 1

[0033] The Chinese medicine composition formula that is used to prevent and treat dengue fever virus among the embodiment 1 is as follows:

[0034] Artemisia annua extract 180g, Perilla extract 300g and Wulingzhi 70g.

[0035] The preparation process of the Chinese medicine composition for preventing and treating dengue virus of embodiment 1 is as follows:

[0036] Grind and pulverize the fresh whole herb of Artemisia annua, add 0.3% sodium carbonate solution of 2 times its mass, soak for 5 hours, beat, stand and filter to obtain Artemisia annua filtrate; then evaporate and crystallize the Artemisia annua filtrate, evaporate The crystallization temperature is 30°C to obtain the Artemisia annua extract;

[0037] Dry the whole perilla plant at 50°C for 36 hours, take it out and pulverize it to obtain perilla powder; use water as the extractant for ultrasonic extraction, the ultrasonic power is 360w, and the weight ratio of perilla powder to water is 1:10 , the temperature is 8...

Embodiment 2

[0041] The Chinese medicine composition formula that is used to prevent and treat dengue fever virus among the embodiment 2 is as follows:

[0042] Artemisia annua extract 200g, Perilla extract 200g and Wulingzhi 110g;

[0043] The preparation process of the Chinese medicine composition for preventing and treating dengue fever virus of embodiment 2 is as follows:

[0044] Grind and pulverize the fresh whole herb of Artemisia annua, add 0.4% sodium carbonate solution with a concentration three times its mass, soak for 6 hours, beat, stand and filter to obtain Artemisia annua filtrate; then evaporate and crystallize the Artemisia annua filtrate, evaporate The crystallization temperature is 40°C to obtain the Artemisia annua extract;

[0045] Dry the whole perilla plant at 50°C for 48 hours, take it out and pulverize it to obtain perilla powder; use water as the extractant for ultrasonic extraction, the ultrasonic power is 400w, and the weight ratio of perilla powder to water is...

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Abstract

The invention is applicable to the technical field of medicines, and provides a traditional Chinese medicine composition for preventing and treating dengue virus and a preparation method thereof. Thetraditional Chinese medicine composition is prepared from plant-derived traditional Chinese medicine raw materials including an artemisia apiacea extract, a purple perilla extract and trogopterus dungthrough compatibility. The traditional Chinese medicine composition has a good prevention and treatment effect on dengue fever, dengue hemorrhagic fever and dengue heat shock syndrome caused by dengue virus infection, is long in drug effect time and good in curative effect, and particularly has a good inhibition effect on dengue fever type II viruses.

Description

technical field [0001] The invention belongs to the technical field of medicine, in particular to a traditional Chinese medicine composition for preventing and treating dengue virus and a preparation method thereof. Background technique [0002] Dengue virus belongs to Flaviviridae and Flavivirus genus in classification. Including 4 different serotypes, namely I, II, III, IV dengue virus. Dengue fever is an acute infectious disease caused by dengue virus. It is mainly transmitted by Aedes aegypti and Aedes albopictus. The main clinical manifestations are high fever, headache, muscle and joint pain, rash, enlarged lymph nodes and leukopenia, etc. In severe cases, hemorrhage or shock may occur, and even death. In early 2019, WHO listed dengue disease caused by dengue virus as one of the top ten threats to global health in 2019. From the beginning of 2019 to the end of August, dengue fever outbreaks have occurred frequently in more than 20 countries and regions around the wo...

Claims

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Application Information

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IPC IPC(8): A61K36/535A61P31/14A61K35/24
CPCA61K35/24A61K36/282A61K36/535A61P31/14A61K2300/00Y02A50/30
Inventor 陈伟明陈钦荣翁聪聪
Owner 广东卫康有害生物防制有限公司
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