Solid beverage containing recombinant human auxin microcapsules and preparation method thereof

A technology for solid beverages and growth hormones, which is used in medical preparations containing active ingredients, microcapsules, and medical preparations without active ingredients, etc., to achieve high drug embedding rate, uniform and controllable particle size, and improved bone strength. Effect

Inactive Publication Date: 2020-10-13
上海圣岳生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, there is no oral recombinant human growth hormone product on the market, and it can only be effective through injection

Method used

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  • Solid beverage containing recombinant human auxin microcapsules and preparation method thereof
  • Solid beverage containing recombinant human auxin microcapsules and preparation method thereof
  • Solid beverage containing recombinant human auxin microcapsules and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0049] Example 1: as figure 1 , a solid beverage containing recombinant human growth hormone microcapsules, each component and its corresponding parts by weight are shown in Table 1, and are prepared by the following steps:

[0050] (1) sieving: pass each raw material component through a 20-mesh sieve, for subsequent use;

[0051] (2) Weighing: according to the formula dosage, the raw materials are weighed in turn. During the weighing process, one person weighs the material and one person reviews it;

[0052] (3) premix: vitamin D, sucralose and recombinant human growth hormone microcapsules are mixed in equal amounts for 5min to obtain a premix;

[0053] (4) Mixing: mix the premix with calcium gluconate, casein phosphopeptide, non-dairy creamer, anhydrous citric acid, compound essence, xanthan gum and the remaining vitamin D and sucralose for 30min; wherein the compound essence is composed of The weight ratio is 2:1:1 mixed with yogurt flavor powder, blueberry flavor and po...

Embodiment 2-6

[0061] Example 2-6: A solid beverage containing recombinant human growth hormone microcapsules, which is different from Example 1 in that each component and its corresponding parts by weight are shown in Table 1.

[0062] Table 1 Components and their parts by weight in Examples 1-6

[0063]

Embodiment 7

[0064] Embodiment 7: a solid beverage containing recombinant human growth hormone microcapsules, which is different from embodiment 1 in that the solid beverage is prepared by the following steps:

[0065] (1) sieving: pass each raw material component through a 20-mesh sieve, for subsequent use;

[0066] (2) Weighing: according to the formula dosage, the raw materials are weighed in turn. During the weighing process, one person weighs the material and one person reviews it;

[0067] (3) premix: vitamin D, sucralose and recombinant human growth hormone microcapsules are mixed in equal amounts for 10min to obtain a premix;

[0068] (4) Mixing: mix the premix with calcium gluconate, casein phosphopeptide, non-dairy creamer, anhydrous citric acid, compound essence, xanthan gum and the remaining vitamin D and sucralose for 45min; wherein the compound essence is composed of The weight ratio is 8:1:1 mixed with yogurt flavor powder essence, blueberry essence and powder fresh creamer...

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Abstract

The invention discloses a solid beverage containing recombinant human auxin microcapsules and a preparation method thereof, and relates to the technical field of solid beverages. The solid beverage containing the recombinant human auxin microcapsules is characterized by comprising the following components in parts by weight: 0.22-3.35 parts of recombinant human auxin microcapsules, 40-60 parts ofcalcium gluconate, 0.003-0.005 part of vitamin D, 8-12 parts of casein phosphopeptides, 150-230 parts of non-dairy creamer, 2.4-3.6 parts of anhydrous citric acid, 0.5-0.8 part of sucralose, 7-10 parts of xanthan gum and 13-20 parts of compound essence. The preparation method comprises the following steps: (1) screening; (2) weighing; (3) premixing; (4) mixing; (5) subpackaging and filling; and (6) packaging and warehousing. The solid beverage prepared by the method has the advantages of nutrition, health and improvement of bone strength; and by embedding the recombinant human auxin, the solidbeverage can be directly orally taken, and still has the advantages of high bioactivity and stability.

Description

technical field [0001] The invention relates to the technical field of solid beverages, and more particularly, to a solid beverage containing recombinant human growth hormone microcapsules and a preparation method thereof. Background technique [0002] In 1920, people discovered the existence of growth hormone (humangrowthhormone, hGH). Growth hormone is a protein secreted by adenohypophyseal cells. It is a peptide hormone composed of 191 amino acid residues and has a relative molecular mass of 22124 Daltons. Growth hormone molecular structure has 4 alpha helices, so that growth hormone can be well combined with its receptors. In 1958, it was discovered that human growth hormone could be used to treat dwarfism. However, because human growth hormone could only be extracted from the pituitary gland of cadavers at that time, the quantity was limited, and it was difficult to guarantee the clinical dosage, thus limiting its application. In 1986, Boyer successfully synthesized re...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A23L2/39A23L2/395A23L33/16A23L33/18A23L33/17A23P10/30A23L33/155A61K38/27A61K9/50A61K9/14A61K47/32A61P19/08A61P19/10
CPCA23L2/39A23L2/395A23L33/16A23L33/18A23L33/17A23P10/30A23L33/155A61K9/5026A61K38/27A61K31/191A61K31/59A61K9/0095A61K9/148A61P19/10A61P19/08A23V2002/00
Inventor 楼秀余吴锦青施明杰杨佩娟
Owner 上海圣岳生物科技有限公司
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