The invention discloses a dendrobium officinale, fruit and vegetable beverage which is prepared from the following raw materials in parts by weight: 17-22 parts of dendrobium officinale, 12-18 parts of oat fibers, 2-4 parts of water caltrop stems, 6-8 parts of rice vinegar, 8-9 parts of grape syrup, 0.9-1.1 parts of fraxinus mandshurica, 3-5 parts of shrimp sauce, 2-4 parts of cherry-apple tree leaves, 8-10 parts of corn gluten meal, 8-9 parts of apple powder, 9-12 parts of bitter gourds, 12-13 parts of celery leaves, 12-14 parts of soybean milk, 3-4 parts of lily flowers, 1-2 parts of herbs of sessile skullcap, 6-7 parts of edible cactus, 10-12 parts of carrot juice, 8-10 parts of semen coicis, 10-12 parts of nutrient additives and a proper amount of water. The beverage disclosed by the invention contains the shrimp sauce, various vegetable and fruit juices, is high in protein content, and contains abundant mineral substances such as potassium, iodine, magnesium and phosphorus, as well as other components such as vitamin A and aminophylline so as to be rich in nutrition; in addition, the dendrobium officinale, fruit and vegetable beverage contains various Chinese herbal medicine extracting solutions, is used for clearing liver and improving vision and can also be used for preventing cold headache and wind-heat clouded vision; and the dendrobium officinale, fruit and vegetable beverage can also be used for beautifying, is good in drinking taste, and has the preventing and health-care effects.