The invention provides non-spherical
polymer particles uniform in particle size as well as a preparation method and an application of the non-spherical
polymer particles. The non-spherical
polymer particles are in the form of ellipsoids, short rods or fibers, and the interiors of the non-spherical polymer particles are of
solid, hollow or porous structures; the short
diameter of the non-spherical polymer particles ranges from 100nm to 30[micron]m, the long
diameter of the non-spherical polymer particles is 1-60[micron]m, the ratio of the long
diameter to the short diameter is 2-40, and the
particle size distribution coefficient of the particles is less than 20%. The non-spherical polymer particles disclosed by the invention, which are uniform and controllable in particle size, are prepared by taking
disodium hydrogen phosphate and / or
sodium dihydrogen
phosphate as a deformation inducing agent and by taking the influence of such conditions as the concentration of the
disodium hydrogen phosphate and / or
sodium dihydrogen
phosphate, self-properties of a polymer,
mass concentration of the polymer in an
oil phase, the size of
emulsion drops and the like into comprehensive consideration; the non-spherical polymer particles can be applied to various fields such as biological
drug delivery, vaccine adjuvants, enzymatic
catalysis, bio-separation, human
tissue engineering field and the like; and the preparation method is simple to operate, mild in condition and easy for industrial enlarged production.