Developing composite material, preparation method and application thereof, implantable and interventional medical instrument and preparation method of implantable and interventional medical instrument

A composite material and medical device technology, which is applied in the field of vascular embolization device, vascular stent or occluder and their preparation and development of composite materials, can solve the problem that the development material cannot be developed well, and achieves the effect of a simple preparation method

Pending Publication Date: 2020-10-13
BEIJING ADVANCED MEDICAL TECH
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  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0011] In order to solve the defect that existing developing materials cannot be well developed for small-sized medical devices in the prior art, the present invention provides a developing composite material, which also has good developing effect for small-sized medical devices

Method used

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  • Developing composite material, preparation method and application thereof, implantable and interventional medical instrument and preparation method of implantable and interventional medical instrument
  • Developing composite material, preparation method and application thereof, implantable and interventional medical instrument and preparation method of implantable and interventional medical instrument
  • Developing composite material, preparation method and application thereof, implantable and interventional medical instrument and preparation method of implantable and interventional medical instrument

Examples

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Effect test

Embodiment 1

[0101] The imaging composite material, by weight percentage, is made of the following raw materials: 45% non-developing polymer, 50% radiopacity modifier and 5% surfactant. Wherein, the non-developing polymer is polycaprolactone (PCL), the radiopacity improving agent is iopromide, and the surfactant is glycerin.

[0102] The preparation method of developing composite material is as follows:

[0103] (1) According to the formula, weigh the prepared raw materials, blend them, crush them in a wall breaker, and stir them evenly; among them, the non-developing polymers can be granules, powders, or debris;

[0104] (2) Melting and stirring: melting and stirring devices such as figure 1 As shown, first put the raw materials in a heating container to preheat, melt and stir, let the materials mix thoroughly, until the mixture can pull out filaments, and can be used for normal extrusion after granulation;

[0105] (3) Extruded into filaments, the diameter of the filaments is 0.58±0.05...

Embodiment 21

[0135] The difference from Example 1 is that the wire diameter is 0.7±0.05mm, and the structure and its developing effect are as follows: image 3 with 4 shown.

Embodiment 22

[0137] The difference from Example 1 is that the wire diameter is 0.85±0.05mm, and the structure and its developing effect are as follows: Figure 5 with 6 shown.

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Abstract

The invention provides a developing composite material and a preparation method thereof. The composite material is prepared from the following raw materials in percentage by weight: 20%-80% of non-developing high-molecular polymer, 80%-20% of impermeability improver and 0-10% of surface active agent. When the composite material is prepared, a melting stirrer or an extruder is adopted for materialmixing or even mixing in a solvent, the solvent is removed, and then the composite material is granulated or extruded into wires or used for preparing medical instruments. Furthermore, the invention provides application of the composite material, an implantable and interventional medical instrument adopting the composite material and a preparation method of the instrument. The composite material is filamentous and also has a good developing effect, and the developing composite material which has a developer content exceeding 50% and is suitable for an extrusion process can be prepared by utilizing the method. The medical instrument prepared from the composite material has a good developing effect and is beneficial to intraoperative operation and postoperative follow-up visit.

Description

technical field [0001] The invention belongs to a composite material used for medical devices, and in particular relates to a developing composite material. At the same time, it also relates to a preparation method and application of the composite material, and also relates to a blood vessel embolization device or a blood vessel stent or an occluder and a preparation method thereof. Background technique [0002] Aneurysm is a disease caused by the change of blood vessel wall structure and hemodynamics caused by various factors. Its wall is thin, and once it ruptures, the patient will face life-threatening. [0003] The previous treatment was mainly based on surgical clipping and artificial blood vessel replacement. In the past half a century, minimally invasive endovascular embolization interventional therapy has emerged. The intervention process is simple, the patient has less bleeding, and the postoperative recovery is quick. In 1974, Serbineko first used a detachable bal...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/18A61L31/14A61L31/06A61L31/02G16C60/00
CPCA61L31/18A61L31/148A61L31/14A61L31/06A61L31/028G16C60/00C08L67/04
Inventor 赵清华冯汉卿吴斯倞刘青赵庆洪穆士卿
Owner BEIJING ADVANCED MEDICAL TECH
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