A kind of compound rattan pepper gel and preparation method thereof
A compound vine pepper and gel technology is applied in the directions of pharmaceutical formulations, medical preparations with inactive ingredients, and medical preparations containing active ingredients, etc. Convenience and other issues, to achieve the effect of no lumps, good appearance, uniform and fine texture
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Embodiment 1
[0036] The screening of embodiment 1 gel matrix
[0037] Weigh appropriate amounts of carbomer, polyvinyl alcohol, chitosan, and sodium alginate respectively, place them in a beaker, add distilled water to fully swell, and make carbomer into 1% and 3% gel solutions; polyethylene Alcohol is made into 5%, 10% gel solution; Chitosan is made into 2%, 5% gel solution with 10% acetic acid aqueous solution (with 10% acetic acid aqueous solution); Sodium alginate is made into 5% %, 10% gel solution, observe the gel formation of each matrix, see Table 1.
[0038] Table 1 Gel matrix screening results
[0039]
[0040] It can be seen from Table 1 that carbomer, chitosan, and sodium alginate can all form gels, but 10% polyvinyl alcohol cannot form gels. Combining the above-mentioned gel matrix fluidity, uniformity, and viscosity and other related indicators, the selected Adding 1% carbomer, 2% chitosan and 5% sodium alginate into the drug and experimental research on mixing and formi...
Embodiment 2
[0050] Weigh 1.5g of the prescribed amount of carbomer, add appropriate amount of water and stir evenly to make it fully swell overnight. Weigh 4.5g of fine powdered camphor in the prescribed amount, add it into the fully swollen gel matrix, and stir evenly. Measure 25ml of glycerol (glycerol) and add it to the fully swollen gel matrix, take the prescription amount of cinnamon extract fine powder 3g and put it into a beaker, add an appropriate amount of deionized water and mix well, then add it to the above gel matrix and stir uniform. Accurately weigh 7.5 g of the prescription amount of rattan pepper essential oil in a beaker, add 25 ml of the prescription amount of propylene glycol to dissolve and mix, then add to the above gel matrix and stir evenly. Then add 0.1 g of ethylparaben and then add 0.25 ml of triethanolamine in the prescribed amount, and finally add distilled water to 150 g.
[0051] According to Table 3, the gel in Example 2 was given a comprehensive score of...
Embodiment 3
[0053] Weigh 1.5g of the prescribed amount of carbomer, add appropriate amount of water and stir evenly to make it fully swell overnight. Weigh 4.5g of fine powdered camphor in the prescribed amount, add it into the fully swollen gel matrix, and stir evenly. Measure 30ml of glycerol (glycerol) and add it to the fully swollen gel matrix, take the prescription amount of cinnamon extract fine powder 3g and put it into a beaker, add an appropriate amount of deionized water and mix well, then add it to the above gel matrix and stir uniform. Accurately weigh 7.5 g of the prescription amount of rattan pepper essential oil in a beaker, add 35 ml of the prescription amount of propylene glycol to dissolve and mix, then add it to the above-mentioned gel matrix and stir evenly. Then add 0.1 g of ethylparaben, then add 0.5 ml of triethanolamine in the prescribed amount, and finally add distilled water to 150 g.
[0054] According to Table 3, the gel in Example 3 was given a comprehensive...
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