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Contrast barium sulfate jelly and preparation method thereof

A technology of barium sulfate and barium sulfate powder, which is applied in the preparation of X-ray contrast agents, pharmaceutical formulations, preparations for in vivo tests, etc., can solve the problems of contrast agent residue and inconvenient use, and achieve stable performance, convenient consumption, Reasonable effect

Inactive Publication Date: 2021-02-09
李昭 +1
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] For this reason, the embodiment of the present invention provides a contrast barium sulfate jelly and its preparation method to solve the problems of inconvenient use and possible contrast agent residue in the prior art contrast barium sulfate powder

Method used

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  • Contrast barium sulfate jelly and preparation method thereof
  • Contrast barium sulfate jelly and preparation method thereof

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Embodiment 1

[0022] The preparation method of the contrast barium sulfate jelly of the present embodiment comprises the following steps:

[0023] 1) Prepare the following components: 20% barium sulfate powder, 12% potassium sorbate, 18% vitamin C, 10% citric acid, 40% xanthan gum;

[0024] 2) Add barium sulfate powder, potassium sorbate, vitamin C, citric acid, and xanthan gum into water in sequence, heat under stirring conditions, and then fill, wherein, the amount of water added is barium sulfate powder, potassium sorbate, 10% of the total weight of vitamin C and xanthan gum, the heating temperature is 50°C, and the heating time is 30min;

[0025] 3) Seal it, sterilize it, let it cool down to room temperature, and get ready.

Embodiment 2

[0027] The preparation method of the contrast barium sulfate jelly of the present embodiment comprises the following steps:

[0028] 1) Prepare the following components: barium sulfate powder 22%, potassium sorbate 15%, vitamin C 15%, citric acid 10%, pectin 38%;

[0029] 2) Add barium sulfate powder, potassium sorbate, vitamin C, citric acid, and pectin into water in sequence, heat under stirring conditions, and then fill; the amount of water added is barium sulfate powder, potassium sorbate, vitamin C, 12% of the total weight of citric acid and pectin, the heating temperature is 55°C, and the heating time is 30min;

[0030] 3) Seal, sterilize, and cool to room temperature.

Embodiment 3

[0032] The preparation method of the contrast barium sulfate jelly of the present embodiment comprises the following steps:

[0033] 1) Prepare the following components: barium sulfate powder 24%, potassium sorbate 12%, vitamin C 8%, citric acid 18%, konjac gum 38%;

[0034] 2) Add barium sulfate powder, potassium sorbate, vitamin C, citric acid, and konjac gum into water in sequence, heat under stirring conditions, and then fill; the amount of water added is barium sulfate powder, potassium sorbate, vitamin C, 15% of the total weight of citric acid and konjac gum, the heating temperature is 55°C, and the heating time is 35min;

[0035] 3) Seal, sterilize, and cool to room temperature.

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Abstract

The embodiment of the invention discloses contrast barium sulfate jelly and a preparation method thereof, and belongs to the technical field of contrast agents. The contrast barium sulfate jelly is prepared from the following components in percentage by weight: 20-25% of barium sulfate powder, 38-42% of a jelly food additive and 35-40% of edible gum. The contrast barium sulfate jelly is prepared from the barium sulfate powder, the jelly food additives and the edible gum in a specific weight ratio as raw materials through a proper process, is unique in formula and reasonable in proportion, is basically consistent with the barium sulfate powder in proportion, is convenient to eat, is further easy to discharge, and is remarkable in clinical contrast effect; the complex process of temporary blending before barium sulfate powder contrast is avoided; meanwhile, the jelly food additives are added, the taste is easy to accept, the performance is stable, and long-term storage can be achieved; in the examination of digestive tract (gastrointestinal tract) diseases, accurate examination and diagnosis can be carried out, so that the treatment is more convenient; and the contrast barium sulfatejelly is suitable for wide-range popularization.

Description

technical field [0001] The embodiments of the present invention relate to the technical field of contrast agents, in particular to a contrast barium sulfate jelly and a preparation method thereof. Background technique [0002] For nearly a century, medical staff have used barium sulfate as the drug of choice for the examination of the digestive tract (gastrointestinal tract), such as esophageal barium meal, small intestinal dilute barium contrast, gas barium colonography, and defecation contrast. "Barium sulfate powder" is mixed with water to form a paste. Because barium sulfate is insoluble in water, it is easy to precipitate due to its high specificity. It needs to be stirred frequently, which brings a lot of inconvenience during use. [0003] At the same time, the paste mixed with "barium sulfate powder" and water is like our daily building material "cement". Constipation and other timely excretion in the body, due to the long residence time in the digestive tract (gastr...

Claims

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Application Information

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IPC IPC(8): A61K49/04
CPCA61K49/0404
Inventor 李昭李岩徐振锋蔡俊锋彭昕
Owner 李昭